Mechanisms Underlying Phasic and Sustained Secretion in Chromaffin Cells from Mouse Adrenal Slices

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

1998 • 2,377 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

1994 • 1,485 citations

Co‐operative action of calcium ions in transmitter release at the neuromuscular junction

1967 • 1,326 citations

Vesicle Pools and Ca2+ Microdomains: New Tools for Understanding Their Roles in Neurotransmitter Release

1998 • 1,021 citations

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.

1982 • 1,010 citations

Calcium dependence of the rate of exocytosis in a synaptic terminal

1994 • 746 citations

Two components of transmitter release at a central synapse.

1994 • 528 citations

Transport, docking and exocytosis of single secretory granules in live chromaffin cells

1997 • 437 citations

Protein Kinase C Enhances Exocytosis from Chromaffin Cells by Increasing the Size of the Readily Releasable Pool of Secretory Granules

1996 • 395 citations

Localization of calcium signals by a mobile calcium buffer in frog saccular hair cells

1994 • 343 citations

Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+

1994 • 343 citations

Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis

1995 • 341 citations

Docked granules, the exocytic burst, and the need for ATP hydrolysis in endocrine cells

1995 • 337 citations

Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity

1998 • 337 citations

A Ca-Dependent Early Step in the Release of Catecholamines from Adrenal Chromaffin Cells

1993 • 312 citations

Modeling Buffered Ca2+ Diffusion Near the Membrane

1997 • 285 citations

Folding intermediates of SNARE complex assembly.

1999 • 272 citations

Regulation of the Readily Releasable Vesicle Pool by Protein Kinase C

1998 • 261 citations

Ultrafast Exocytosis Elicited by Calcium Current in Synaptic Terminals of Retinal Bipolar Neurons

1996 • 259 citations

Releasable pools and the kinetics of exocytosis in adrenal chromaffin cells

1994 • 254 citations

A low affinity Ca2+ receptor controls the final steps in peptide secretion from pituitary melanotrophs

1993 • 243 citations

Cytosolic Ca 2+ Acts by Two Separate Pathways to Modulate the Supply of Release-Competent Vesicles in Chromaffin Cells

1998 • 228 citations

A two-step model of secretion control in neuroendocrine cells

1993 • 204 citations

Ultrastructural Organization of Bovine Chromaffin Cell Cortex—Analysis by Cryofixation and Morphometry of Aspects Pertinent to Exocytosis

1997 • 198 citations

Time course of Ca2+ concentration triggering exocytosis in neuroendocrine cells.

1994 • 191 citations

Time courses of calcium and calcium-bound buffers following calcium influx in a model cell

1993 • 186 citations

Comparative biology of Ca2+-dependent exocytosis: implications of kinetic diversity for secretory function

1999 • 179 citations

Delayed release of transmitter at the frog neuromuscular junction

1973 • 166 citations

Submillisecond Kinetics of Glutamate Release from a Sensory Synapse

1998 • 162 citations

Rapid Exocytosis in Single Chromaffin Cells Recorded from Mouse Adrenal Slices

1997 • 147 citations

Colocalization of calcium entry and exocytotic release sites in adrenal chromaffin cells.

1995 • 134 citations

Rapid exocytosis and endocytosis in nerve terminals of the rat posterior pituitary.

1996 • 102 citations

Kinetic diversity in the fusion of exocytotic vesicles

1997 • 81 citations

Estimation of mean exocytic vesicle capacitance in mouse adrenal chromaffin cells

1997 • 75 citations

Multiple stimulation-dependent processes regulate the size of the releasable pool of vesicles

1999 • 69 citations

Kinetics of stimulus-coupled secretion in dialyzed bovine chromaffin cells in response to trains of depolarizing pulses

1996 • 67 citations

Two components of transmitter release in retinal bipolar cells: exocytosis and mobilization of synaptic vesicles

1997 • 58 citations

Potentiation of transmitter release by protein kinase C in goldfish retinal bipolar cells

1998 • 38 citations

Two components of transmitter release from the chick ciliary presynaptic terminal and their regulation by protein kinase C

1999 • 20 citations