Detection of Mutated K12-ras in Histologically Negative Lymph Nodes as an Indicator of Poor Prognosis in Stage II Colorectal Cancer

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Kirsten ras Mutations in Patients With Colorectal Cancer: the Multicenter "RASCAL" Study

1998 • 739 citations

Micrometastases and Survival in Stage II Colorectal Cancer

1998 • 602 citations

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1983 • 553 citations

Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: a Southwest Oncology Group study.

1998 • 338 citations

For patients with dukes' B (TNM stage II) colorectal carcinoma, examination of six or fewer lymph nodes is Related to poor prognosis

1998 • 312 citations

Genetic diagnosis of lymph-node metastasis in colorectal cancer

1995 • 289 citations

Detection of disseminated colorectal cancer cells in lymph nodes, blood and bone marrow.

1999 • 149 citations

Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method.

1994 • 108 citations

Review article: Micrometastasis in colorectal carcinoma: A review

1998 • 106 citations

Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.

1999 • 91 citations

Restriction Endonuclease-Mediated Selective Polymerase Chain Reaction

1998 • 76 citations

Automated closed-vessel system for in vitro diagnostics based on polymerase chain reaction

1993 • 62 citations

Efficacy of adjuvant fluorouracil and leucovorin in stage B2 and C colon cancer

2001 • 57 citations

Genetic detection of colorectal cancer cells in circulation and lymph nodes

1997 • 56 citations

Efficacy of adjuvant fluorouracil and leucovorin in stage B2 and C colon cancer

2001 • 47 citations

Molecular staging of colorectal cancer

2000 • 36 citations

Rapid, Sensitive Detection of Mutant Alleles in Codon 12 of K-ras by REMS-PCR

1999 • 8 citations