Biochemical effects and drug levels in rats after long-term treatment with the specific 5-HT-uptake inhibitor, citalopram

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Probability and Statistics for Engineers.

1965 • 1,060 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

1969 • 645 citations

Receptor Sensitivity and the Mechanism of Action of Antidepressant Treatment

1981 • 645 citations

Citalopram — Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity

1982 • 589 citations

Diagnosis and Drug Treatment of Psychiatric Disorders

1970 • 534 citations

How to analyze binding, enzyme and uptake data: The simplest case, a single phase

1982 • 262 citations

Probability and Statistics for Engineers

1966 • 249 citations

On the Slowness of Action of Tricyclic Antidepressant Drugs

1972 • 226 citations

Action of mianserin and zimelidine on the norepinephrine receptor coupled adenylate cyclase system in brain: Subsensitivity without reduction in β-adrenergic receptor binding

1980 • 178 citations

Neurochemical characterization of a new potent and selective serotonin uptake inhibitor: Lu 10-171

1977 • 174 citations

A rapid accurate procedure for the determination of serotonin in whole human blood

1970 • 146 citations

Zimelidine: A therapeutic and pharmacokinetic study in depression

1979 • 115 citations

The Kinetics of Citalopram: Single and Multiple Dose Studies in Man

1981 • 113 citations

Current concepts on the mechanisms of action of antidepressant drugs

1981 • 112 citations

Kinetics of citalopram in man; plasma levels in patients

1982 • 111 citations

Effect of a specific 5-HT uptake inhibitor, citalopram (Lu 10-171), on 3H-5-HT uptake in rat brain synaptosomes in vitro

1978 • 87 citations

Kinetics of citalopram in test animals; drug exposure in safety studies

1982 • 80 citations

A double–blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression

1982 • 71 citations

Effects of zimelidine on serotoninergic and noradrenergic neurons after repeated administration in the rat

1981 • 69 citations

A noradrenaline sensitive adenylate cyclase in the rat limbic forebrain: Preparation, properties and the effects of agonists, adrenolytics and neuroleptic drugs

1976 • 66 citations

Citalopram, a selective serotonin reuptake inhibitor: Clinical antidepressive and long-term effect ? a phase II study

1982 • 61 citations

Effect of norepinephrine uptake blocker on β-adrenergic receptors of the rat cerebral cortex

1981 • 57 citations

Subsensitivity of the norepinephrine receptor-coupled adenylate cyclase system in brain: Effects of Nisoxetine versus fluoxetine

1979 • 55 citations

Initial, clinical trial of a new, specific 5‐HT reuptake inhibitor, citalopram (Lu 10–171)

1980 • 44 citations

A Possible Role of Serotonin Receptors in Antidepressant Drug Action

1982 • 36 citations

Citalopram — A specific 5-HT-reuptake inhibitor — As an antidepressant drug: A phase II multicentre trial

1982 • 31 citations

Fluorescence assay of citalopram and its metabolites in plasma by scanning densitometry of thin-layer chromatograms

1981 • 23 citations

Central 5-HTP decarboxylase inhibiting properties of Ro 4-4602 in relation to 5-HTP potentiation in mice

1972 • 21 citations

Preliminary studies with citalopram (Lu 10-171), a specific 5-HT-reup-take inhibitor, as antidepressant

1982 • 20 citations

Acute versus chronic effects of serotonin uptake blockers on potentiation of the "serotonin syndrome".

1980 • 16 citations

Treatment of affective disorders.

1985 • 14 citations

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