Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

1998 • 2,076 citations

Calcitonin gene-related peptide is a potent vasodilator

1985 • 2,050 citations

Nitric oxide and pregnancy

1997 • 684 citations

Selective Amplification And Cloning Of Four New Members Of The G Protein-coupled Receptor Family

1989 • 647 citations

Calcitonin Gene-Related Peptide and Its Receptors: Molecular Genetics, Physiology, Pathophysiology, and Therapeutic Potentials

1996 • 488 citations

Multiple Amylin Receptors Arise from Receptor Activity-Modifying Protein Interaction with the Calcitonin Receptor Gene Product

1999 • 469 citations

Amylin, Calcitonin Gene-Related Peptide, Calcitonin, and Adrenomedullin: A Peptide Superfamily

1997 • 419 citations

ENDOCRINOLOGY OF PREGNANCY

1955 • 381 citations

A second human calcitonin/CGRP gene

1985 • 363 citations

Calcitonin gene-related peptide in cardiovascular tissues of the rat

1985 • 338 citations

Cloning and Expression of cDNA Encoding a Rat Adrenomedullin Receptor

1995 • 294 citations

The Endocrinology of Pregnancy

1997 • 276 citations

Ontogeny of peptide‐ and amine‐containing neurones in motor, sensory, and autonomic regions of rat and human spinal cord, dorsal root ganglia, and rat skin

1987 • 260 citations

An Amylin Receptor Is Revealed Following Co-Transfection of a Calcitonin Receptor with Receptor Activity Modifying Proteins-1 or -3

1999 • 255 citations

Possible involvement of two proteins (phosphoprotein and CD9(p24)) in regulation of platelet calcium fluxes

1985 • 243 citations

Calcitonin gene-related peptide: Multiple actions, multiple receptors

1992 • 226 citations

Neuropeptide expression in cultures of adult sensory neurons: Modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor

1989 • 221 citations

Nitric oxide and pregnancy

1997 • 216 citations

Peptides from the calcitonin genes: molecular genetics, structure and function

1988 • 187 citations

Characterization of CGRP₁ and CGRP₂ Receptor Subtypesa

1992 • 185 citations

Identification of an Orphan Receptor Gene as a Type 1 Calcitonin Gene-Related Peptide Receptor

1995 • 179 citations

RAMPs: accessory proteins for seven transmembrane domain receptors

1999 • 154 citations

Doppler assessment of the uterine and uteroplacental circulation in the second trimester in pregnancies at high risk for pre‐eclampsia and/or intrauterine growth retardation: comparison and correlation between different Doppler parameters

1997 • 153 citations

Transvaginal uterine and umbilical artery Doppler examination of 12–16 weeks and the subsequent development of pre‐eclampsia and intrauterine growth retardation

1997 • 150 citations

A Receptor Activity Modifying Protein (RAMP)2-Dependent Adrenomedullin Receptor Is a Calcitonin Gene-Related Peptide Receptor when Coexpressed with Human RAMP1*

1999 • 150 citations

Cloning and expression of the human vasoactive intestinal peptide receptor.

1991 • 149 citations

Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine.

1991 • 146 citations

Increased Blood Pressure in α-Calcitonin Gene–Related Peptide/Calcitonin Gene Knockout Mice

2000 • 143 citations

Maternal Cardiovascular and Other Physiologic Responses to the Endocrinology of Pregnancy

1998 • 143 citations

A New Calcitonin-Receptor-like Sequence in Rat Pulmonary Blood Vessels

1993 • 138 citations

Increased concentration of circulating calcitonin gene related peptide during normal human pregnancy.

1986 • 134 citations

The RAMP2/CRLR complex is a functional adrenomedullin receptor in human endothelial and vascular smooth muscle cells

1999 • 125 citations

Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay.

1996 • 121 citations

Localization of binding sites for calcitonin gene-related peptide in rat brain by in vitro autoradiography

1986 • 103 citations

Regional Distribution of Calcitonin Gene-Related Peptide and Its Specific Binding Sites in Rats with Particular Reference to the Nervous System

1987 • 101 citations

Neuropeptide expression by newborn and adult rat sensory neurons in culture: Effects of nerve growth factor and other neurotrophic factors

1994 • 101 citations

Role and regulation of nitric oxide in the uterus during pregnancy and parturition

1998 • 95 citations

Antagonistic effect of human α-CGRP [8–37] on the in vivo regional haemodynamic actions of human α-CGRP

1990 • 95 citations

Regulation of Calcitonin Gene-Related Peptide Expression in Dorsal Root Ganglia of Rats by Female Sex Steroid Hormones1

2000 • 94 citations

An Amylin Receptor Is Revealed Following Co-Transfection of a Calcitonin Receptor with Receptor Activity Modifying Proteins-1 or -3

1999 • 93 citations

Pregnancy-induced uterine neuronal degeneration in the rat

1997 • 91 citations

Endothelial vasodilator production by uterine and systemic arteries. VI. Ovarian and pregnancy effects on eNOS and NO_x

2001 • 89 citations

Calcitonin gene-related peptide inhibits spontaneous contractions in human uterus and fallopian tube

1985 • 84 citations

Effect of bradykinin and prostaglandins on the release of calcitonin gene‐related peptide‐like immunoreactivity from the rat spinal cord in vitro

1993 • 83 citations

Immunocytochemical analysis of sex differences in calcitonin gene-related peptide in the rat dorsal root ganglion, with special reference to estrogen and its receptor

1998 • 81 citations

Nitric oxide nerves in the uterus are parasympathetic, sensory, and contain neuropeptides

1995 • 73 citations

Dose-Dependent Systemic and Regional Hemodynamic Effects of Calcitonin Gene-Related Peptide

1989 • 72 citations

Hormonal influence on calcitonin gene-related peptide in man: effects of sex difference and contraceptive pills

1990 • 67 citations

Female Steroid Hormones Modulate Receptors for Nerve Growth Factor in Rat Dorsal Root Ganglia1

2001 • 67 citations

Calcitonin Gene-Related Peptide Is a Depressor in N ^G -Nitro- <scp>l</scp> -Arginine Methyl Ester-Induced Hypertension During Pregnancy

1997 • 66 citations

Pregnancy and sex steroid hormones enhance circulating calcitonin gene-related peptide concentrations in rats

2000 • 65 citations

Calcitonin gene-related peptide reverses the hypertension and significantly decreases the fetal mortality in pre-eclampsia rats induced by NG-nitro-L-arginine methyl ester

1996 • 64 citations

Involvement of calcitonin gene–related peptide in the modulation of human myometrial contractility during pregnancy

1999 • 60 citations

Systemic capsaicin in the adult rat differentially affects gene expression for neuropeptides and neurotrophin receptors in primary sensory neurons

1996 • 59 citations

Vasodilator Effects of Parathyroid Hormone, Parathyroid Hormone-Related Protein, and Calcitonin Gene-Related Peptide in the Human Fetal-Placental Circulation

1994 • 56 citations

A Receptor Activity Modifying Protein (RAMP)2-Dependent Adrenomedullin Receptor Is a Calcitonin Gene-Related Peptide Receptor when Coexpressed with Human RAMP1

1999 • 54 citations

Comparative study of distribution and biochemical characterization of brain calcitonin gene-related peptide receptors in five different species

1993 • 52 citations

Molecular Cloning of a Novel Human Receptor Gene with Homology to the Rat Adrenomedullin Receptor and High Expression in Heart and Immune System

1997 • 51 citations

Pregnancy and steroid hormones enhance the vasodilation responses to CGRP in rats

1999 • 48 citations

Receptor for calcitonin gene-related peptide: localization in the dorsal and ventral spinal cord

1999 • 47 citations

Calcitonin gene-related peptide and its specific binding sites in the cardiovascular system of rat

1988 • 46 citations

Nonadrenergic noncholinergic nerves regulate basal coronary flow via release of capsaicin-sensitive neuropeptides in the rat heart.

1994 • 43 citations

Monoclonal antibodies reveal expression of the CGRP receptor in Purkinje cells, interneurons and astrocytes of rat cerebellar cortex

1998 • 42 citations

Infusion of Pregnant Rats with Calcitonin Gene-Related Peptide (CGRP)8-37, a CGRP Receptor Antagonist, Increases Blood Pressure and Fetal Mortality and Decreases Fetal Growth1

2002 • 40 citations

Inhibitory Effect of Calcitonin Gene-Related Peptide on Myometrial Contractility Is Diminished at Parturition¹

1997 • 38 citations

Progesterone up-regulates vasodilator effects of calcitonin gene–related peptide in NG-nitro-l-arginine methyl ester–induced hypertension

1997 • 37 citations

Galanin-immunoreactive nerves in the female rat paracervical ganglion and uterine cervix: distribution and reaction to capsaicin

1989 • 35 citations

Hormonal replacement therapy affects calcitonin gene-related peptide and atrial natriuretic peptide secretion in postmenopausal women

1997 • 33 citations

Regulation of Calcitonin Gene-Related Peptide Receptors in the Rat Uterus During Pregnancy and Labor and by Progesterone1

1999 • 33 citations

Galanin and calcitonin gene-related peptide immunoreactivity in nerves of the rat uterus: Localization, colocalization, and effects on uterine contractility

1992 • 33 citations

Pregnancy and Steroid Hormones Enhance the Systemic and Regional Hemodynamic Effects of Calcitonin Gene-Related Peptide in Rats1

2001 • 32 citations

Relaxant effect of the calcitonin gene-related peptide (CGRP) on the nonpregnant and pregnant rat uterus. Comparison with vascular tissue

1998 • 30 citations

Both α- and β-calcitonin gene-related peptides are present in plasma, cerebrospinal fluid and spinal cord in man

1989 • 29 citations

Uterine relaxation responses to calcitonin gene–related peptide and calcitonin gene–related peptide receptors decreased during labor in rats

1998 • 28 citations

Inhibition of rat uterine contractions by rat and human CGRP

1990 • 28 citations

Tissue-specific mRNA expression of a calcitonin receptor-like receptor during fetal and postnatal development

1997 • 27 citations

Possible physiologic role of calcitonin gene-related peptide in the human uterine artery

1993 • 25 citations

Characterization of the RDC1 gene which encodes the canine omolog of a proposed human VIP receptor Expression does not correlate with an increase in VIP binding sites

1992 • 25 citations

Solubilization and characterization of a guanine nucleotide-sensitive form of the calcitonin gene-related peptide receptor.

1993 • 24 citations

Gestational Changes in Calcitonin Gene-Related Peptide, Nerve Growth Factor, and Its Receptors in Rat Dorsal Root Ganglia1

2001 • 23 citations

Effects of calcitonin gene-related peptide on vascular resistance in rats: role of sex steroids

1999 • 23 citations

Calcitonin gene-related peptide – a new concept in receptor–ligand specificity?

1998 • 22 citations

Human α- and β-calcitonin gene-related peptides are vasodilators in human chorionic plate vasculature

1989 • 20 citations

Relaxation by calcitonin gene-related peptide may involve activation of K+ channels in the human uterine artery

1993 • 19 citations

Inhibitory Effect of Calcitonin Gene-Related Peptide on Myometrial Contractility Is Diminished at Parturition

1997 • 17 citations

Regional and cellular localization of calcitonin gene-related peptide-receptor component protein mRNA in the guinea-pig central nervous system

1999 • 17 citations

Alteration of capsaicin and endotoxin-induced calcitonin gene-related peptide release from mesenteric arterial bed and spinal cord slice in 18-month-old rats

1998 • 13 citations

Effect of calcitonin gene-related peptide on the uterine vasculature of the nonpregnant ewe

1992 • 7 citations

Down‐Regulation of CGRP‐Mediated cAMP Accumulation in ras‐Transformed 3T3 Fibroblasts

1992 • 6 citations

Variations of circulating calcitonin gene related peptide levels during pregnancy and perinatal-period

1989 • 5 citations

Calcitonin Gene-Related Peptide (CGRP) receptor binding and localization in nonpregnant and pregnant rat uterus and regulation by sex steroid hormones

1998 • 2 citations