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Dichloromethylene diphosphonate (Cl2MDP) reduces natural killer (NK) cell activity in mice

Data up to Jan 2025

Published1984
Citations16
References34

Total Citations Per Year

Abstract

References (34)

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

Natural Killer Cells: Their Roles in Defenses Against Disease

1981 • 1,353 citations

Natural Cell-Mediated Immunity

1978 • 1,063 citations

Diphosphonates Inhibit Hydroxyapatite Dissolution in vitro and Bone Resorption in Tissue Culture and in vivo

1969 • 758 citations

Role of NK cells in tumour growth and metastasis in beige mice

1980 • 524 citations

The beige mutation in the mouse selectively impairs natural killer cell function

1979 • 467 citations

Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

1977 • 467 citations

Definitive evidence that natural killer (NK) cells inhibit experimental tumor metastases in vivo.

1981 • 395 citations

An Analysis of the Murine NK Cell as to Structure, Function and Biological Relevance

1979 • 351 citations

beta-Estradiol reduces natural killer cells in mice.

1978 • 216 citations

Natural Killer Cells in the Mouse: An Alternative Immune Surveillance Mechanism?

1978 • 205 citations

Suppression of Natural Killer Cell Activity with Radioactive Strontium: Effector Cells Are Marrow Dependent

1977 • 193 citations

Current Advances in Skeletogenesis

1983 • 179 citations

Role of macrophages in the augementation of mouse natural killer cell activity by poly I:C and interferon.

1979 • 170 citations

Low natural in vivo resistance to syngeneic leukaemias in natural killer-deficient mice

1980 • 165 citations

Current concepts in human immunology and cancer immunomodulation

1981 • 141 citations

β-Estradiol Reduces Natural Killer Cells in Mice

1978 • 139 citations

Natural Killer Cells, Bone, and the Bone Marrow: Studies in Estrogen-Treated Mice and in Congenitally Osteopetrotic (mi/mi) Mice

1979 • 129 citations

Role of Macrophages in the Augmentation of Mouse Natural Killer Cell Activity by Poly I:C and Interferon

1979 • 121 citations

The effect of dichloromethylene diphosphonate, a pyrophosphate analog, on bone and bone cell structure in the growing rat

1979 • 115 citations

The hematogenous origin of osteoclasts: Experimental evidence from osteopetrotic (microphthalmic) mice treated with spleen cells from beige mouse donors

1981 • 114 citations

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1950 • 108 citations

The alteration of osteoclast morphology by diphosphonates in bone organ culture

1976 • 76 citations

Positive correlation between in vitro NK activity and in vivo resistance towards AKR lymphoma cells

1980 • 54 citations

Inhibition by diphosphonates of bone resorption in mice and comparison with grey-lethal osteopetrosis

1973 • 50 citations

The peritoneal antigen‐presenting macrophage: control and immunogenic properties of distinct subpopulations

1981 • 42 citations

The pathogenesis of infantile malignant osteopetrosis: Bone mineral metabolism and complications in five infants

1981 • 41 citations

Immunological defect and its correction in the osteopetrotic mutant rat.

1977 • 35 citations

Thymus and Osteopetrosis

1978 • 32 citations

(Dichloromethylene)diphosphonate-induced impairment of T-lymphocyte function.

1983 • 31 citations

Variation in selectivity of tumor cell cytolysis by murine macrophages, macrophage-like cell lines and NK cells

1982 • 31 citations

Thymus-derived lymphocytes control the expression of immunogenic properties of peritoneal macrophages.

1979 • 16 citations

Lack of a T-cell dependent subpopulation of macrophages in (dichloromethylene) diphosphonate-treated mice.

1983 • 14 citations

Coexistence of defective and normal immunologic functions in lymphocytes and macrophages from osteopetrotic (op) rats.

1982 • 13 citations

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Dichloromethylene diphosphonate (Cl2MDP) reduces natural killer (NK) cell activity in mice (1984) – Metabolic Bone Disease and Related Research | Metascience Observatory Explorer