Activation of interleukin‐ 1β by a co‐induced protease

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

There is more than one interleukin 1

1986 • 1,226 citations

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1982 • 1,024 citations

Proteinases in mammalian cells and tissues

1978 • 981 citations

Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

1988 • 377 citations

The kinetics of interleukin 1 secretion from activated monocytes. Differences between interleukin 1 alpha and interleukin 1 beta.

1988 • 249 citations

Interleukin 1 beta is localized in the cytoplasmic ground substance but is largely absent from the Golgi apparatus and plasma membranes of stimulated human monocytes.

1988 • 152 citations

Human interleukin 1. Purification to homogeneity.

1985 • 107 citations

Immunocytochemical detection of interleukin 1 within stimulated human monocytes.

1986 • 105 citations

Human interleukin 1 beta is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA.

1988 • 87 citations

Purification and biochemical characteristics of two distinct human interleukins 1 from the myelomonocytic THP-1 cell line

1986 • 42 citations