Epidermal growth factor receptor, HER-2/neu and related pathways in lung adenocarcinomas with bronchioloalveolar features

The Hallmarks of Cancer

2000 • 27,569 citations

Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

2001 • 11,070 citations

Untangling the ErbB signalling network

2001 • 6,623 citations

Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

2003 • 3,532 citations

Regulation of Cell Death Protease Caspase-9 by Phosphorylation

1998 • 3,129 citations

Histological Typing of Lung and Pleural Tumours

1999 • 1,538 citations

Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on Prognosis

2003 • 1,445 citations

Single-molecule imaging of EGFR signalling on the surface of living cells

2000 • 884 citations

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand‐receptor interactions

1997 • 719 citations

Assessment of Methods for Tissue-Based Detection of the HER-2/neu Alteration in Human Breast Cancer: A Direct Comparison of Fluorescence In Situ Hybridization and Immunohistochemistry

2000 • 690 citations

Why the Epidermal Growth Factor Receptor? The Rationale for Cancer Therapy

2002 • 482 citations

Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression.

1997 • 404 citations

Randomized phase II trial of gemcitabine–cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer

2003 • 374 citations

ErbB-2 Amplification Inhibits Down-regulation and Induces Constitutive Activation of Both ErbB-2 and Epidermal Growth Factor Receptors

1999 • 332 citations

Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways.

2003 • 326 citations

Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: amphiregulin and microvessel count are independent prognostic indicators of survival.

1998 • 305 citations

Epidermal growth factor receptor family in lung cancer and premalignancy

2002 • 303 citations

Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas

2002 • 233 citations

Primary Mucinous (So-called Colloid) Carcinomas of the Lung

2004 • 174 citations

Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC)

2003 • 130 citations

The role of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature

2003 • 112 citations

HER2/neu expression in malignant lung tumors

2002 • 102 citations

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2002 • 101 citations

Clinical Characteristics of Pneumonic-Type Adenocarcinoma of the Lunga

2003 • 97 citations

Expression of cytokeratin 20 in mucinous bronchioloalveolar carcinoma

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Bronchioloalveolar Lung Carcinoma

1998 • 71 citations

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Reclassification of Cystic Bronchioloalveolar Carcinomas to Adenocarcinomas Based on the Revised World Health Organization Classification of Lung and Pleural Tumours

2003 • 19 citations

O-187 ZD1839 (iressa) in advanced bronchioloalveolar carcinoma (BAC): A preliminary report of SWOG SO126

2003 • 14 citations