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Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection

Data up to Jan 2025

Published1991
Citations149
References29

Total Citations Per Year

Abstract

References (29)

Quantitation of Human Immunodeficiency Virus Type 1 in the Blood of Infected Persons

1989 • 1,090 citations

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

1988 • 532 citations

Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

1988 • 467 citations

Dextran Sulfate Suppression of Viruses in the HIV Family: Inhibition of Virion Binding to CD4 + Cells

1988 • 465 citations

2′,3′-Dideoxyinosine (ddI) in Patients with the Acquired Immunodeficiency Syndrome or AIDS-Related Complex

1990 • 391 citations

Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro

1987 • 320 citations

HIV-1 Reverse Transcriptase Is a Target for Cytotoxic T Lymphocytes in Infected Individuals

1988 • 270 citations

Kinetics of intravenously administered heparin in normal humans

1982 • 220 citations

Circulating p24 Antigen Levels and Responses to Dideoxycytidine in Human Immunodeficiency Virus (HIV) Infections

1989 • 211 citations

Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro

1988 • 194 citations

Kinetics of intravenously administered heparin in normal humans

1982 • 194 citations

Recombinant Soluble CD4 Therapy in Patients with the Acquired Immunodeficiency Syndrome (AIDS) and AIDS-Related Complex

1990 • 186 citations

Human Immunodeficiency Virus (HIV) Antigenemia (p24) in the Acquired Immunodeficiency Syndrome (AIDS) and the Effect of Treatment with Zidovudine (AZT)

1988 • 140 citations

Oral Dextran Sulfate (UAOO1) in the Treatment of the Acquired Immunodeficiency Syndrome (AIDS) and AIDS-Related Complex

1989 • 134 citations

Dextran Sulfate Is Poorly Absorbed after Oral Administration

1989 • 133 citations

The Safety and Pharmacokinetics of Recombinant Soluble CD4 (rCD4) in Subjects with the Acquired Immunodeficiency Syndrome (AIDS) and AIDS-Related Complex

1990 • 133 citations

Effects of passive immunization in patients with the acquired immunodeficiency syndrome-related complex and acquired immunodeficiency syndrome.

1988 • 106 citations

Flow cytometric method to demonstrate whether anti-HIV-1 agents inhibit virion binding to T4+ cells.

1989 • 85 citations

Effect of Foscarnet therapy on infection with human immunodeficiency virus in patients with AIDS.

1988 • 80 citations

Immunomodulating activity of heparin

1991 • 60 citations

Effect of Zidovudine on Serum Human Immunodeficiency Virus Core Antigen Levels

1988 • 55 citations

Intracellular interference with antigen presentation.

1988 • 54 citations

A study of the in vitro and in vivo effects of a synthetic heparin-like anticoagulant: dextran sulphate.

1957 • 41 citations

THERAPEUTIC TRIAL OF THE SYNTHETIC HEPARIN ANALOGUE DEXTRAN SULPHATE

1953 • 31 citations

DRUG REACTIONS XXIII.

1973 • 31 citations

Influence of sulfated carbohydrates on the accessibility of CD4 and other CD molecules on the cell surface and implications for human immunodeficiency virus infection

1989 • 29 citations

Alopecia following Treatment with Dextran Sulphate and Other Anticoagulant Drugs

1958 • 19 citations

Activation of murine B cells with Salmonella typhimurium mitogen (STM), lipopolysaccharide (LPS), and dextran sulfate (DxS). I. Cell-cycle analysis and induction of cytoplasmic immunoglobulin.

1987 • 6 citations

HIV Antigen Variability in ARC/AIDS

1991 • 3 citations

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Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human… (1991) – Antimicrobial Agents and Chemotherapy | Metascience Observatory Explorer