Proton NMR study of the [d(ACGTATACGT)]₂-2echinomycin complex: conformational changes between echinomycin binding sites

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1980 • 1,886 citations

Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG.

1982 • 626 citations

Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods

1983 • 548 citations

DNA structural variations in the E. coli tyrT promoter

1984 • 448 citations

The Molecular Structure of a DNA-Triostin A Complex

1984 • 294 citations

Echinomycin: a bifunctional intercalating antibiotic

1974 • 281 citations

Interactions of antitumor drugs with natural DNA: proton NMR study of binding mode and kinetics

1984 • 278 citations

Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)

1983 • 219 citations

Echinomycin Binding Sites on DNA

1984 • 218 citations

A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment

1985 • 215 citations

Principles of Nucleic Acid Structure

2021 • 184 citations

Sequence-specific binding of echinomycin to DNA: evidence for conformational changes affecting flanking sequences

1984 • 178 citations

NMR studies of echinomycin bisintercalation complexes with d(A1-C2-G3-T4) and d(T1-C2-G3-A4) duplexes in aqueous solution: sequence-dependent formation of Hoogsteen A1.cntdot.T4 and Watson-Crick T1.cntdot.A4 base pairs flanking the bisintercalation site

1988 • 100 citations

Antitumour drug–DNA interactions: NMR studies of echinomycin and chromomycin complexes

1989 • 85 citations

Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex.

1989 • 76 citations

Two-dimensional NMR investigation of a bent DNA fragment: assignment of the proton resonances and preliminary structure analysis

1987 • 74 citations

The DNA sequence at echinomycin binding sites determines the structural changes induced by drug binding: NMR studies of echinomycin binding to [d(ACGTACGT)]2 and [d(TCGATCGA)]2

1991 • 61 citations

Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA.

1987 • 61 citations

Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening

1992 • 48 citations

Theoretical studies of nucleic acid interactions. I. Estimates of conformational mobility in intercalated chains

1983 • 38 citations

Proton NMR studies of [N-MeCys3,N-MeCys7]TANDEM binding to DNA oligonucleotides: sequence-specific binding at the TpA site

1992 • 28 citations

Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs.

1989 • 28 citations

Phase I trial of echinomycin (NSC 526417), a bifunctional intercalating agent, administered by 24-hour continuous infusion

1989 • 15 citations

Echinomycin binding to the sequence CG(AT)_nCG alters the structure of the central AT region

1990 • 13 citations

Hoogsteen versus Watson‐Crick A‐T basepairing in DNA complexes of a new group of ‘quinomycin‐like’ antibiotics

1990 • 11 citations

Conformation and dynamics of the deoxyribose rings of a (nogalamycin)2–d (5′-GCATGC)2 complex studied in solution by 1H-n.m.r. spectroscopy

1990 • 9 citations