Detection of DNA cross‐links in tumor cells with the ethidium bromide fluorescence assay

A fluorescent complex between ethidium bromide and nucleic acids

1967 • 2,351 citations

A new fluorometric method for RNA and DNA determination

1966 • 644 citations

Improvements in the ethidium bromide method for direct fluorometric estimation of DNA and RNA in cell and tissue homogenates

1977 • 278 citations

DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum(II) and L-phenylalanine mustard.

1981 • 213 citations

Studies related to antitumor antibiotics. Part V. Reactions of mitomycin C with DNA examined by ethidium fluorescence assay

1976 • 167 citations

Native and denatured DNA, cross-linked and palindromic DNA and circular covalently-closed DNA analysed by a sensitive fluorometric procedure

1974 • 125 citations

Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts.

1984 • 97 citations

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) II. Comparison of results from alkaline elution, DNA renaturation and DNA sedimentation studies

1981 • 70 citations

DNA cross-linking and cytotoxicity induced by cis-diamminedichloroplatinum(II) in human normal and tumor cell lines.

1981 • 59 citations

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) I. Proportion of DNA-platinum reactions involved in DNA crosslinking

1981 • 58 citations

Differential cytotoxicity and DNA cross-linking in normal and transformed human fibroblasts treated with cis-diamminedichloroplatinum(II).

1981 • 50 citations

A Fluorescence Assay for DNA with Covalently Linked Complementary Sequences

1972 • 27 citations

Measurements of DNA and RNA in mammary gland homogenates by the ethidium bromide technique

1975 • 21 citations