Conditional inactivation of the TGF‐β type II receptor using Cre:Lox

Transforming Growth Factor-β1 Mediates Epithelial to Mesenchymal Transdifferentiation through a RhoA-dependent Mechanism

2001 • 993 citations

TGF-β Receptor Type II Deficiency Results in Defects of Yolk Sac Hematopoiesis and Vasculogenesis

1996 • 651 citations

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

1998 • 494 citations

Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects

1999 • 436 citations

[53] Manipulation of transgenes by site-specific recombination: Use of cre recombinase

1993 • 342 citations

Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2

1998 • 295 citations

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

1993 • 260 citations

Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in‐situ and invasive carcinomas

2000 • 118 citations

The Genomic Structure of the Gene Encoding the Human Transforming Growth Factor β Type II Receptor (TGF-β RII)

1996 • 34 citations

The Bin1 Gene Localizes to Human Chromosome 2q14 by PCR Analysis of Somatic Cell Hybrids and Fluorescencein SituHybridization

1996 • 27 citations

Transforming growth factor beta and its receptors: their role in breast cancer

2000 • 10 citations

The TGFβ Type II Receptor,Tgfbr2,Maps to Distal Mouse Chromosome 9

1996 • 7 citations