Biological Function of HLA

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

Histocompatibility-Linked Immune Response Genes

1972 • 1,194 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 611 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice.

1975 • 454 citations

CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES

1973 • 431 citations

The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens.

1975 • 364 citations

Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursors.

1977 • 357 citations

Y-antigen killing by T cells of women is restricted by HLA

1977 • 326 citations

H-2 Dependence of Co-Operation Between T and B Cells in Vivo

1972 • 285 citations

Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex

1975 • 276 citations

QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS

1968 • 274 citations

HLA restriction of cell-mediated lysis of influenza virus-infected human cells

1977 • 274 citations

Functional Specificity of Thymus-Dependent Lymphocytes

1977 • 256 citations

Responsiveness to HY Antigen Ir Gene Complementation and Target Cell Specificity

1977 • 215 citations

HISTOCOMPATIBILITY-LINKED IMMUNE RESPONSE GENE FUNCTION IN GUINEA PIGS

1972 • 186 citations

Two Different V_H Gene Products Make Up the T‐Cell Receptors

1976 • 179 citations

Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers.

1975 • 172 citations

Functional interactions of viral and histocompatibility antigens at tumor cell surfaces.

1975 • 165 citations

Determinant selection is a macrophage dependent immune response gene function

1977 • 164 citations

T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera.

1976 • 158 citations

H-2 gene complex restricts transfer of delayed-type hypersensitivity in mice.

1975 • 158 citations

Killer cells reactive to altered-self antigens can also be alloreactive.

1977 • 155 citations

The Function and Interrelationships of T‐Cell Receptors, Ir Genes and Other Histocompatibility Gene Products

1975 • 152 citations

HLA‐D Restriction of the Macrophage‐Dependent Response of Immune Human T Lymphocytes to PPD in Vitro: Inhibition by Anti‐HLA‐DR Antisera

1978 • 151 citations

Helper T cells recognize antigen and macrophage surface components simultaneously

1976 • 131 citations

The Clonal Selection Hypothesis Evaluated by Grafted Cells Reacting Against their Hosts

1967 • 121 citations

Cytolytic thymus-derived lymphocytes specific for allogeneic stimulator cells crossreact with chemically modified syngeneic cells.

1977 • 118 citations

Tissue Distribution of Ia Antigens and their Expression on Lymphocyte Subpopulations

1976 • 116 citations

T Lymphocyte-Enriched Murine Peritoneal Exudate Cells

1976 • 114 citations

Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions.

1976 • 112 citations

Selective incorporation of H–2 antigenic determinants into Friend virus particles

1977 • 111 citations

Models for recognition of virally modified cells by immune thymus-derived lymphocytes

1976 • 111 citations

Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. III. Dual gene control of the T-cell-mediated suppression of the antibody response.

1976 • 107 citations

Human cell-mediated cytotoxicity against modified target cells is restricted by HLA

1977 • 103 citations

Exclusive involvement of H-2D(b) or H-2K(d) product in the interaction between T-killer lymphocytes and syngeneic H-2(b) or H-2(d) viral lymphomas

1977 • 102 citations

T-cell idiotypes are linked to immunoglobulin heavy chain genes

1976 • 101 citations

The function of macrophages in antigen recognition by guinea pig T lymphocytes. III. Genetic analysis of the antigens mediating macrophage-T lymphocyte interaction.

1976 • 82 citations

Suppressor-cell induction in vitro. IV. Target of antigen-specific suppressor factor and its genetic relationships.

1978 • 81 citations

T cell receptor idiotypes are controlled by genes in the heavy chain linkage group and the major histocompatibility complex

1977 • 77 citations

The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity

1977 • 71 citations

A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen. Evidence that identity at HLA-D between suppressor and responder is required for suppression.

1978 • 70 citations

The Function of Macrophages in Antigen Recognition by Guinea Pig T Lymphocytes

1976 • 57 citations

H-Y Antigen: Genetics and Serology

1977 • 55 citations

Stimulation of T Lymphocytes by Autologous non-T Lymphoid Cells. Participation of HLA-D?

1977 • 50 citations

Histocompatibility linked immune responsiveness and restrictions imposed on sensitized lymphocytes.

1977 • 46 citations

Sheep red blood cell-specific helper activity in rat thoracic duct lymphocyte populations positively selected for reactivity to specific strong histocompatibility alloantigens.

1976 • 45 citations

Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). I. Production, characterization, and lack of H-2 restriction for activity in recipient strain.

1977 • 38 citations

The Major Histocompatibility Complex: Influence on Immune Reactivity and T-Lymphocyte Activation

1977 • 29 citations

Two-gene control of T-helper cell induction

1976 • 28 citations

Suppressor cells in tolerance to contact sensitivity active against hapten-syngeneic and hapten-allogeneic determinants.

1977 • 28 citations

The guinea pig I region. II. Functional analysis.

1977 • 27 citations

Membrane-bound H–2 and H–Y antigens move independently of each other

1977 • 23 citations

Immunosuppressive Factor(s) Specific for L-Glutamic Acid50-L-Tyrosine50 (GT)

1977 • 22 citations

Cytotoxic T lymphocytes induced against allogeneic I-region determinants react with Ia molecules on trinitrophenyl-conjugated syngeneic target cells

1977 • 21 citations

Rod–cone mechanism underlying the Purkinje shift

1976 • 13 citations