β-Chlorophenyl GABA (Baclofen) is a selective ligand for a novel GABA receptor on nerve terminals

(–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

1980 • 1,091 citations

SIXTH GADDUM MEMORIAL LECTURE NATIONAL INSTITUTE FOR MEDICAL RESEARCH, MILL HILL, JANUARY 1977

1977 • 935 citations

THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS

1960 • 853 citations

PRESYNAPTIC RECEPTORS AND THEIR ROLE IN THE REGULATION OF TRANSMITTER RELEASE.

1977 • 616 citations

Gamma-Aminobutyric Acid Binding to Receptor Sites in the Rat Central Nervous System

1974 • 589 citations

Presynaptic inhibition at the crayfish neuromuscular junction

1961 • 463 citations

Preferential metabolism of (—)-3H-norepinephrine through the deaminated glycol in the rat vas deferens

1973 • 352 citations

A new class of GABA agonist

1977 • 338 citations

Actions of gamma‐aminobutyric acid on sympathetic ganglion cells.

1975 • 269 citations

DEPOLARIZING ACTIONS OF γ‐AMINOBUTYRIC ACID AND RELATED COMPOUNDS ON RAT SUPERIOR CERVICAL GANGLIA IN VITRO

1974 • 249 citations

The biological activity of d-baclofen (Lipresal®)

1978 • 205 citations

Action of baclofen on mammalian synaptic transmission

1978 • 201 citations

Central effects of β-(p-chlorophenyl)-γ-aminobutyric acid

1974 • 191 citations

Axonal GABA-receptors in mammalian peripheral nerve trunks

1978 • 185 citations

BACLOFEN: EFFECTS ON AMINO ACID RELEASE AND METABOLISM IN SLICES OF GUINEA PIG CEREBRAL CORTEX

1979 • 180 citations

STRUCTURE‐ACTIVITY STUDIES ON THE INHIBITION OF GABA BINDING TO RAT BRAIN MEMBRANES BY MUSCIMOL AND RELATED COMPOUNDS

1978 • 176 citations

Amino acids as chemical transmitters

1979 • 158 citations

The actions of gamma-aminobutyric acid and related amino acids on mammalian autonomic ganglia.

1970 • 158 citations

The action of β-phenyl-GABA derivatives on neurones of the cat cerebral cortex

1974 • 147 citations

ACTIONS OF AMINO‐ACIDS ON THE ISOLATED HEMISECTED SPINAL CORD OF THE TOAD

1997 • 139 citations

STRUCTURE‐ACTIVITY DETERMINANTS OF PHARMACOLOGICAL EFFECTS OF AMINO ACIDS AND RELATED COMPOUNDS ON CENTRAL SYNAPSES

1959 • 134 citations

ACTIONS OF AMINO‐ACIDS ON THE ISOLATED HEMISECTED SPINAL CORD OF THE TOAD

1961 • 124 citations

Physiological significance of α-adrenoceptor-mediated negative feedback mechanism regulating noradrenaline release during nerve stimulation

1977 • 92 citations

Studies on the Gamma-Aminobutyric Acid Receptor/Ionophore Proteins in Mammalian Brain

1978 • 80 citations

4-Aminotetrolic Acid : New Conformational-restricted Analogue of γ-Aminobutyric Acid

1971 • 62 citations

gamma-Aminobutyric acid reduces the evoked release of [3H]-noradrenaline from sympathetic nerve terminals [proceedings].

1979 • 51 citations

Baclofen and muscimol: Behavioural and neurochemical sequelae of unilateral intranigral administration and effects on 3H-GABA receptor binding

1979 • 44 citations

A COMPARISON OF γ‐AMINOBUTYRIC ACID AND THE SEMI‐RIGID ANALOGUES 4‐AMINOTETROLIC ACID, 4‐AMINOCROTONIC ACID AND IMIDAZOLE‐4‐ACETIC ACID ON THE ISOLATED SUPERIOR CERVICAL GANGLION OF THE RAT

1976 • 40 citations

A very simple method for recording ganglion depolarization.

1975 • 35 citations

Isoguvacine, isonipecotic acid, muscimol and N-methyl isoguvacine on the GABA receptor in rat sympathetic ganglia

1978 • 30 citations

Pharmacology of (+)- and (−)-baclofen: GABA-dependant rotational behaviour and [3H]GABA receptor binding studies

1979 • 18 citations