11β-Hydroxysteroid dehydrogenase and the short-chain alcohol dehydrogenase (SCAD) superfamily

Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated

1988 • 1,607 citations

Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint

1986 • 1,172 citations

LOCALISATION OF 11β-HYDROXYSTEROID DEHYDROGENASE—TISSUE SPECIFIC PROTECTOR OF THE MINERALOCORTICOID RECEPTOR

1988 • 1,047 citations

A workbench for multiple alignment construction and analysis

1991 • 1,005 citations

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

1990 • 727 citations

Toluene Degradation by Pseudomonas putida F1

1989 • 631 citations

A Syndrome of Apparent Mineralocorticoid Excess Associated with Defects in the Peripheral Metabolism of Cortisol*

1979 • 490 citations

Cloning and Expression of Rat cDNA Encoding Corticosteroid 11β-Dehydrogenase

1989 • 452 citations

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

1991 • 434 citations

Poly-β-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16

1989 • 334 citations

Complete amino acid sequence of human placental 17β‐hydroxysteroid dehydrogenase deduced from cDNA

1988 • 298 citations

Importance of estrogen sulfates in breast cancer

1989 • 230 citations

1lβ-Hydroxysteroid Dehydrogenase Bioactivity and Messenger RNA Expression in Rat Forebrain: Localization in Hypothalamus, Hippocampus, and Cortex*

1990 • 215 citations

The complete amino acid sequence of three alcohol dehydrogenase alleloenzymes (AdhN-11, AdhS and AdhUF) from the fruitfly Drosophila melanogaster

1980 • 180 citations

Nucleotide sequence, transcription and deduced function of a gene involved in polyketide antibiotic synthesis in Streptomyces coelicolor

1988 • 178 citations

llβ-Hydroxysteroid Dehydrogenase Activity in the Renal Target Cells of Aldosterone*

1991 • 121 citations

Purification and structural characterization of placental NAD+-linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family

1990 • 105 citations

Glucitol-specific enzymes of the phosphotransferase system in Escherichia coli. Nucleotide sequence of the gut operon.

1987 • 101 citations

Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action

1990 • 100 citations

Nucleotide sequence of the 2,3-dihydroxybiphenyl dioxygenase gene of Pseudomonas pseudoalcaligenes

1987 • 96 citations

Prokaryotic 20β-hydroxysteroid dehydrogenase is an enzyme of the ‘short-chain, non-metalloenzyme’ alcohol dehydrogenase type

1990 • 85 citations

Extended Region of Nodulation Genes in Rhizobium meliloti 1021. II. Nucleotide Sequence, Transcription Start Sites and Protein Products

1987 • 82 citations

Cloning, sequencing, and expression of the gene coding for bile acid 7 alpha-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708

1991 • 80 citations

Complete amino acid sequence of glucose dehydrogenase from Bacillus megaterium

1984 • 75 citations

A growth factor-repressible gene associated with protein kinase C-mediated inhibition of adipocyte differentiation.

1988 • 73 citations

Human placental estradiol 17.beta.-dehydrogenase: sequence of a histidine-bearing peptide inthe catalytic region

1986 • 64 citations

Tissue-specific expression of an 11 beta-hydroxysteroid dehydrogenase with a truncated N-terminal domain. A potential mechanism for differential intracellular localization within mineralocorticoid target cells.

1992 • 54 citations

Nucleotide sequence and regulation of a gene involved in bile acid 7-dehydroxylation by Eubacterium sp. strain VPI 12708

1988 • 54 citations

METABOLISM OF ANDROGENS IN VITRO BY HUMAN FACIAL AND AXILLARY SKIN

1973 • 45 citations

A common ancestor for human placental 17β‐hydroxysteroid dehydrogenase, Streptomyces coelicolor actIII protein, and Drosophila melanogaster alcohol dehydrogenase

1990 • 42 citations

Evidence for a multigene family involved in bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708

1988 • 40 citations

Ribitol dehydrogenase of Klebsiella aerogenes. Sequence and properties of wild-type and mutant strains

1985 • 35 citations

Effect of carbenoxolone on gastric prostaglandin E₂ levels in patients with peptic ulcer disease following vagal and pentagastrin stimulation

1983 • 34 citations

Studies of androgen metabolism and action in cultured hair and skin cells

1986 • 29 citations

Sequence similarity between Pseudomonas dihydrodiol dehydrogenase, part of the gene cluster that metabolizes polychlorinated biphenyls, and dehydrogenases involved in metabolism of ribitol and glucitol and synthesis of antibiotics and 17 β-oestradiol, testosterone and corticosterone

1990 • 28 citations