Coding capacity of a 35 percent fragment of the polyoma virus genome is sufficient to initiate and maintain cellular transformation.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis

1973 • 1,616 citations

METHODS IN CANCER RESEARCH

1969 • 1,197 citations

Transformation of rat cells by DNA of human adenovirus 5

1973 • 664 citations

Restriction Endonuclease

1976 • 405 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

Studies on In Vitro Transformation by DNA and DNA Fragments of Human Adenoviruses and Simian Virus 40

1974 • 334 citations

Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus

1977 • 211 citations

Characterization of t antigens in polyoma-infected and transformed cells

1978 • 208 citations

Polyma DNA: A Physical Map

1974 • 207 citations

Polyoma gene function required for viral DNA synthesis

1973 • 175 citations

Localization of gene functions in polyoma virus DNA.

1976 • 154 citations

Sequence from early region of polyoma virus DNA containing viral replication origin and encoding small, middle and (part of) large T antigens

1979 • 143 citations

Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus.

1977 • 139 citations

Loss of integrated viral DNA sequences in polyoma-transformed cells is associated with an active viral A function

1979 • 117 citations

New classes of viable deletion mutants in the early region of polyoma virus

1979 • 116 citations

5-Bromo-2′-deoxyuridine Potentiation of Transformation of Rat-Embryo Cells Induced In Vitro by 3-Methylcholanthrene: Induction of Rat Leukemia Virus gs Antigen in Transformed Cells

1973 • 114 citations

Polyoma virus-specific 55K protein isolated from plasma membrane of productively infected cells is virus-codedand important for cell transformation

1979 • 112 citations

State and organization of polyoma virus DNA sequences in transformed rat cell lines

1979 • 110 citations

Virus-specific RNA in Cells Productively Infected or Transformed by Polyoma Virus

1974 • 108 citations

Hr-t and ts-a: Two early gene functions of polyoma virus

1977 • 91 citations

Three species of polyoma virus tumor antigens share common peptides probably near the amino termini of the proteins

1978 • 84 citations

Polyoma Virus - A Study of Wild-type, Mutant and Defective DNAs

1974 • 78 citations

Characterization of a temperature-sensitive mutant of polyoma virus

1970 • 76 citations

State of the viral DNA in rat cells transformed by polyma virus. II. Identification of the cells containing nonintegrated viral DNA and the effect of viral mutations

1977 • 74 citations

The Polyoma virus 100K large T-antigen is not required for the maintenance of transformation

1980 • 73 citations

Complementation between temperature-sensitive (ts) and host range nontransforming (hr-t) mutants of polyoma virus

1977 • 71 citations

Interrupting the early region of polyoma virus DNA enhances tumorigenicity.

1979 • 45 citations

Construction of infectious polyoma hybrid genomes in vitro

1976 • 19 citations