Entry of diazepam and its major metabolite into cerebrospinal fluid

Blood-Brain Barrier in Physiology and Medicine

1976 • 888 citations

Clinical Pharmacokinetics of Diazepam

1978 • 490 citations

Binding of Drugs to Serum Albumin

1976 • 410 citations

Blood–Brain Barrier in Physiology and Medicine

1977 • 395 citations

Diazepam disposition determinants

1980 • 348 citations

Therapeutic Drug Monitoring in Saliva

1978 • 300 citations

Metabolism of diazepam in rat, dog, and man.

1965 • 229 citations

Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat.

1976 • 211 citations

Brain Uptake of Phenytoin, Phenobarbital, and Diazepam

1979 • 119 citations

Blood-Brain Barrier Permeability to Drugs

1974 • 113 citations

Pharmacokinetics of Diazepam in Dogs, Mice and Humans

1971 • 89 citations

Diphenylhydantoin, Phenobarbital, and Primidone in Saliva, Plasma, and Cerebrospinal Fluid

1975 • 87 citations

Anticonvulsant Level in Saliva, Serum, and Cerebrospinal Fluid

1975 • 85 citations

Plasma protein binding of diphenylhydantoin in patients with epilepsy; Agreement between the unbound fraction in plasma and the concentration in the cerebrospinal fluid

1972 • 82 citations

Clinical Pharmacokinetics of Chlordiazepoxide

1978 • 69 citations

Cerebrospinal‐Fluid Concentrations of Diazepam and its Metabolites in Man

1975 • 63 citations

Pharmacokinetic and Clinical Implications of Quinidine Protein Binding

1979 • 61 citations

Plasma and Cerebrospinal Fluid Concentrations of Phenobarbital in Infants Given Single Doses

1974 • 59 citations

Simultaneous determination of diazepam and its metabolites N-desmethyldiazepam, oxydiazepam and oxazepam in plasma and urine of man and dog by means of high-performance liquid chromatography

1979 • 52 citations

Simultaneous gas-chromatographic analysis for diazepam and its major metabolite, desmethyldiazepam, with use of double internal standardization.

1978 • 46 citations

Entry of quinidine into cerebrospinal fluid

1980 • 28 citations

Plasma and cerebrospinal fluid concentrations of chlordiazepoxide and its metabolites in surgical patients

1976 • 20 citations

Intravenous Phenytoin and Phenobarbital: Anticonvulsant Action, Brain Content, and Plasma Binding in Rat

1979 • 20 citations

Cerebrospinal-fluid Concentrations of Nitrazepam in Man

1977 • 17 citations