Three-dimensional structure and antigen binding specificity of antibodies

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Antigen — Antibody Reactions In Gels

1949 • 2,247 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines

1979 • 1,885 citations

A better cell line for making hybridomas secreting specific antibodies

1978 • 1,649 citations

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

1985 • 1,241 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1989 • 989 citations

The Antigenic Structure of Proteins: A Reappraisal

1984 • 957 citations

An efficient general-purpose least-squares refinement program for macromolecular structures

1987 • 871 citations

Interactive computer graphics: FRODO

1985 • 848 citations

Three-dimensional structure of an antibody-antigen complex.

1987 • 615 citations

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase

1987 • 556 citations

On the conformation of the hen egg-white lysozyme molecule

1967 • 429 citations

A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin

1989 • 420 citations

Three-Dimensional Structure of the Fab′ Fragment of a Human Immunoglobulin at 2.8-Å Resolution

1973 • 381 citations

Repeated seeding technique for growing large single crystals of proteins

1981 • 145 citations

Antigen specificity and cross-reactivity of monoclonal anti-lysozyme antibodies

1987 • 132 citations

Three-dimensional structure of Fab R19.9, a monoclonal murine antibody specific for the p-azobenzenearsonate group.

1989 • 72 citations

Crystallization and preliminary X-ray diffraction study of the bacterially expressed Fv from the monoclonal anti-lysozyme antibody D1.3 and of its complex with the antigen, lysozyme

1990 • 61 citations

Constrained-restrained least-squares (CORELS) refinement of proteins and nucleic acids

1985 • 60 citations

Dual conformations of an immunoglobulin light-chain dimer: heterogeneity of antigen specificity and idiotope profile may result from multiple variable-domain interaction mechanisms.

1988 • 35 citations

X-ray crystallographic study of the fab fragments from two human myeloma proteins

1969 • 28 citations

Immunochemical and Crystallographic Studies of Antibody D1.3 in Its Free, Antigen-liganded, and Idiotope-bound States

1989 • 24 citations

A MWPC X-ray diffractometer facility for protein crystallography

1984 • 22 citations

Preliminary crystallographic study of a complex between the Fab fragment of a monoclonal anti-lysozyme antibody (D1.3) and the Fab fragment from an anti-idiotopic antibody against D1.3

1987 • 19 citations

Preliminary crystallographic study of the Fab fragments of two monoclonal anti-2-phenyloxazolone antibodies.

1985 • 17 citations

Crystallization of the fab fragments of monoclonal anti-p-azophenylarsonate antibodies and their complexes with haptens.

1984 • 13 citations

Preliminary crystallographic study of a complex between an heteroclitic anti-hen egg-white lysozyme antibody and the heterologous antigen pheasant egg-white lysozyme

1987 • 13 citations

Nucleotide sequence of the VH,VL regions of an anti-idiotopic antibody reacting with a private idiotope of the anti-lysozyme D1.3 antibody

1990 • 5 citations

Crystallization and preliminary X-ray diffraction studies of antigen-antibody complexes

1988 • 4 citations