Inhibition of natural killing and antibody-dependent cell-mediated cytotoxicity by the plasma protease inhibitor α2-macroglobulin (α2M) and α2M protease complexes

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

1966 • 4,504 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

Metal chelate affinity chromatography, a new approach to protein fractionation

1975 • 2,050 citations

Characteristics of human large granular lymphocytes and relationship to natural killer and K cells

1981 • 1,008 citations

Proteinases in mammalian cells and tissues

1978 • 981 citations

p-Nitrophenyl-p′-guanidinobenzoate HCl: A new active site titrant for trypsin

1967 • 848 citations

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

1979 • 530 citations

Determination of α2-macroglobulin as trypsin-protein esterase

1966 • 372 citations

STUDIES ON HUMAN PLASMA α2-MACROGLOBULIN-ENZYME INTERACTIONS

1973 • 362 citations

Cultured human monocytes synthesize and secrete alpha2-macroglobulin.

1977 • 209 citations

Studies on the mechanism of natural killer (NK) cell-mediated cytotoxicity (CMC). I. Release of cytotoxic factors specific for NK-sensitive target cells (NKCF) during co-culture of NK effector cells with NK target cells.

1982 • 153 citations

Analysis of macrophage surface receptors. I. Binding of alpha-macroglobulin . protease complexes to rabbit alveolar macrophages.

1979 • 150 citations

Uptake of proteinase-α-macroglobulin complexes by macrophages☆

1975 • 127 citations

Purification of human α-2-macroglobulin by chromatography on Cibacron Blue Sepharose

1978 • 94 citations

Studies on the mechanism of natural killer cytotoxicity. II. coculture of human PBL with NK-sensitive or resistant cell lines stimulates release of natural killer cytotoxic factors (NKCF) selectively cytotoxic to NK-sensitive target cells.

1983 • 86 citations

Modulation of the Immune Response by Plasma Protease Inhibitors

1982 • 85 citations

The effects of electrophoretically "slow" and "fast" alpha-2 macroglobulin on mixed lymphocyte cultures.

1981 • 53 citations

Natural killer cell activity in childhood acute lymphoblastic leukaemia in remission

1985 • 45 citations

Alpha-2 macroglobulin-enzyme complexes as suppressors of cellular activity

1978 • 38 citations

Association of α-Macroglobulins with Lymphoid Cells

1973 • 36 citations

Preliminary studies on the synthesis of alpha2-macroglobulin by human lymphocytes in vitro.

1974 • 34 citations

Modulation by α-2 Macroglobulin of Human Lymphocyte Proliferation in Response to Mitogens and Antigen

1976 • 29 citations

Inhibition of activity of human NK and K cells by simple sugars: Discrimination between binding and postbinding events

1984 • 22 citations

Modulation of the Immune Response by Plasma Protease Inhibitors

1982 • 19 citations

The role of protease in immunoregulation

1983 • 18 citations

The human LT system. VIII. A target cell-dependent enzymatic activation step required for the expression of the cytotoxic activity of human lymphotoxin.

1980 • 17 citations

Studies on the Quaternary Structure of Human Serum α2-Macroglobulin

1974 • 14 citations

A POSSIBLE MECHANISM OF IMMUNOREGULATION PRODUCED BY α₂‐MACROGLOBULIN

1983 • 7 citations