Investigation of the combination of the agonist D-Trp-6-LH-RH and the antiandrogen flutamide in the treatment of dunning R-3327H prostate cancer model

Tumor growth inhibition in patients with prostatic carcinoma treated with luteinizing hormone-releasing hormone agonists.

1982 • 364 citations

Antagonistic effect of androgen on prostatic cell death

1984 • 339 citations

New approach in the treatment of prostate cancer: Complete instead of partial withdrawal of androgens

1983 • 296 citations

New hormonal therapy in prostatic carcinoma: combined treatment with an LHRH agonist and an antiandrogen.

1982 • 273 citations

Hormonal Effects on Cell Proliferation in Rat Prostate

1976 • 264 citations

The Fine Structure and Histochemistry of Prostatic Glands in Relation to Sex Hormones

1966 • 216 citations

Polymerization of deoxyribonucleotides in relation to androgen-induced prostatic growth

1968 • 208 citations

Extra-pituitary inhibition of testicular function by luteinising hormone releasing hormone

1979 • 158 citations

Inhibition of prostate tumor growth in two rat models by chronic administration of D-Trp6 analogue of luteinizing hormone-releasing hormone.

1981 • 149 citations

POTENT INHIBITORY ACTIVITY OF [D-LEU⁶, DES-GLY-NH₂1Q]LHRH ETHYLAMIDE ON LH/hCG AND PRL TESTICULAR RECEPTOR LEVELS IN THE RAT

1977 • 145 citations

Long-acting delivery systems for peptides: inhibition of rat prostate tumors by controlled release of [D-Trp6]luteinizing hormone-releasing hormone from injectable microcapsules.

1984 • 144 citations

Physiologic Basis for Hormonal Therapy in Carcinoma of the Prostate

1975 • 139 citations

Physiologic basis for hormonal theapy in carcinoma of the prostate.

1975 • 138 citations

Pituitary Gonadotropin Inhibition by a Highly Active Analog of Luteinizing Hormone-Releasing Hormone

1978 • 138 citations

Antitumor Effects of Analogs of Hypothalamic Hormones in Endocrine-Dependent Cancers

1984 • 133 citations

Treatment with gonadotrophin releasing hormone analogue in advanced prostatic cancer.

1983 • 124 citations

The effects of testosterone, 5α-dihydrotestosterone and adenosine 3′,5′-monophosphate on cell proliferation and differentiation in RAT prostate

1973 • 115 citations

Ultrastructural studies on prostatic involution in the rat. Mechanism of autophagy in epithelial cells, with special reference to the rough-surfaced endoplasmic reticulum

1971 • 115 citations

Delay of Puberty and Inhibition of Reproductive Processes in the rat by a Gonadotropin-Releasing Hormone Agonist Analog

1976 • 104 citations

Effect of very high dose D-leucine6-gonadotropin-releasing hormone proethylamide on the hypothalamic-pituitary testicular axis in patients with prostatic cancer.

1983 • 104 citations

LH‐RH Agonists and Antagonists

1980 • 96 citations

Plasma Testosterone Levels in Patients with Prostatic Carcinoma Before and after Treatment

1968 • 94 citations

Current Status of Bilateral Adrenalectomy or Advanced Prostatic Carcinoma

1974 • 90 citations

Sch 13521 In The Treatment Of Advanced Carcinoma Of The Prostate

1974 • 90 citations

The pure antiandrogen ru 23908 (anandron®), a candidate of choice for the combined antihormonal treatment of prostatic cancer: A review

1984 • 89 citations

Recent Approaches to Fertility Control Based on Derivatives of LH-RH

1981 • 87 citations

Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma

1984 • 86 citations

THERAPEUTIC POTENTIAL OF THE LHRH AGONIST, ICI 118630, IN THE TREATMENT OF ADVANCED PROSTATIC CARCINOMA

1983 • 83 citations

From contraception to cancer: a review of the therapeutic applications of LHRH analogues as antitumor agents.

1982 • 80 citations

Advanced carcinoma of the prostate: treatment with a gonadotrophin releasing hormone agonist.

1983 • 78 citations

Physiology of castration-induced regression in rat prostate.

1981 • 78 citations

Cyproterone Acetate in the Treatment of Advanced Carcinoma of the Prostate

1973 • 74 citations

Suppression of Plasma Androgens by Spironolactone in Castrated Men with Carcinoma of the Prostate

1975 • 73 citations

TREATMENT OF ADVANCED PROSTATIC CANCER WITH LHRH ANALOGUE ICI 118630: CLINICAL RESPONSE AND HORMONAL MECHANISMS

1983 • 67 citations

TREATMENT OF PATIENTS WITH ADVANCED CANCER OF THE PROSTATE USING A SLOW-RELEASE (DEPOT) FORMULATION OF THE LHRH AGONIST ICI 118630 (ZOLADEX®)

1984 • 65 citations

Simultaneous administration of pure antiandrogens, a combination necessary for the use of luteinizing hormone-releasing hormone agonists in the treatment of prostate cancer.

1984 • 65 citations

THE EFFECTS OF CASTRATION AND ANDROGEN REPLACEMENT ON THE NUCLEIC ACID COMPOSITION, METABOLISM, AND ENZYMATIC CAPACITIES OF THE RAT VENTRAL PROSTATE

1958 • 63 citations

Cardiovascular complications to treatment of prostate cancer with estramustine phosphate (Estracyt) or conventional estrogen. A follow-up of 212 randomized patients.

1980 • 62 citations

The anti-reproductive pharmacology of LH-RH and agonistic analogues.

1978 • 61 citations

Inhibition of prostate tumors by agonistic and antagonistic analogs of LH‐RH

1983 • 60 citations

Inhibition of the action of sex steroids by gonadotropin-releasing hormone (GnRH) agonists: A new biological effect

1981 • 60 citations

Advanced prostatic carcinoma Flutamide therapy after conventional endocrine treatment

1975 • 56 citations

Partial inhibition of castration induced ventral prostate regression with actinomycin D and cycloheximide.

1978 • 55 citations

Aminoglutethimide Medical Adrenalectomy for Advanced Prostatic Carcinoma

1976 • 54 citations

Gonadotropin-Releasing Hormone Analogues for Prostate Cancer: Untoward Side Effects of High-Dose Regimens Acquire a Therapeutical Dimension

1982 • 50 citations

New hormonal treatment in cancer of the prostate: Combined administration of an LHRH agonist and an antiandrogen

1983 • 47 citations

Treatment of prostatic cancer with LH‐RH analogues

1983 • 42 citations

Mechanism of Androgenic Action: Effect of Specific Intracellular Inhibitors

1971 • 40 citations

Combination of long-acting microcapsules of the D-tryptophan-6 analog of luteinizing hormone-releasing hormone with chemotherapy: investigation in the rat prostate cancer model.

1985 • 38 citations

The effect of orchiectomy and various doses of stilbestrol on plasma testosterone levels in patients with carcinoma of the prostate.

1972 • 36 citations

Comparison of various hormonal therapies for prostatic carcinoma.

1983 • 32 citations

Gonadotropin‐releasing hormone agonistic analogues in the treatment of advanced prostatic carcinoma

1983 • 28 citations

A new antiprostatic agent for treatment of prostatic carcinoma.

1973 • 27 citations

Androgen-Stimulated Restoration in Rat Seminal Vesicle and Prostate Epithelial Cells

1969 • 26 citations

Prolonged Suppression of Plasma LH Levels in Male Rats after a Single Injection of an LH‐RH Agonist in Poly(DL‐Lactide‐Co‐Glycolide) Microcapsules

1985 • 26 citations

Early combined hormonal and chemotherapy for metastatic carcinoma of prostate

1980 • 23 citations

Cyproterone acetate, testosterone, LH, FSH, and prolactin levels in plasma after intramuscular application of cyproterone acetate in patients with prostatic cancer

1981 • 12 citations

An oriented phase-II trial ofd-Trp6-LH-RH in patients with prostatic carcinoma

1984 • 11 citations

Inhibition of the growth of some hormone dependent tumors byd-Trp6-LH-RH

1984 • 9 citations