Are platelets the link between depression and ischemic heart disease?

Depression Following Myocardial Infarction

1993 • 1,958 citations

Depression and 18-Month Prognosis After Myocardial Infarction

1995 • 1,594 citations

The Relationship of Depression to Cardiovascular Disease

1998 • 1,560 citations

Symptoms of Depression, Acute Myocardial Infarction, and Total Mortality in a Community Sample

1996 • 867 citations

Depressed Affect, Hopelessness, and the Risk of Ischemic Heart Disease in a Cohort of U.S. Adults

1993 • 789 citations

Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine

1995 • 769 citations

Exaggerated platelet reactivity in major depression

1996 • 575 citations

Tritiated Imipramine Binding Sites Are Decreased in Platelets of Untreated Depressed Patients

1980 • 440 citations

Long-term Protection From Myocardial Ischemic Events in a Randomized Trial of Brief Integrin β3 Blockade With Percutaneous Coronary Intervention

1997 • 399 citations

Elevated platelet factor 4 and β-thromboglobulin plasma levels in depressed patients with ischemic heart disease

1997 • 349 citations

Change in Depression as a Precursor of Cardiovascular Events

1996 • 323 citations

Depressed Patients Have Decreased Binding of Tritiated Imipramine to Platelet Serotonin 'Transporter'

1981 • 317 citations

Definition of insanity.

1984 • 292 citations

Depressive Symptomatology and Hypertension-Associated Morbidity and Mortality in Older Adults

1995 • 228 citations

Platelet activation and secretion associated with emotional stress.

1985 • 198 citations

Evaluation of Platelet Activation in Depressed Patients With Ischemic Heart Disease After Paroxetine or Nortriptyline Treatment

2000 • 197 citations

Platelets and coronary heart disease: potential psychophysiologic mechanisms.

1991 • 174 citations

Increased serotonin2 (5-HT2) receptor binding as measured by 3H-lysergic acid diethylamide (3H-LSD) in the blood platelets of depressed patients

1989 • 170 citations

Altered platelet function during mental stress and adrenaline infusion in humans: evidence for an increased aggregability in vivo as measured by filtragometry

1989 • 122 citations

Further studies on platelet serotonin transporter binding in depression

1994 • 97 citations

Serotonin 5-HT2 receptor binding on blood platelets as a state dependent marker in major affective disorder

1990 • 82 citations

Increased reactivity of platelets induced by fibrinogen independent of its binding to the IIb-IIIa surface glycoprotein:

1999 • 74 citations

CORRELATION OF TYPE A BEHAVIOUR WITH ADRENERGIC RECEPTOR DENSITY: IMPLICATIONS FOR CORONARY ARTERY DISEASE PATHOGENESIS

1987 • 23 citations

Awareness of High Blood Pressure Stimulates Platelet Release Reaction

1990 • 22 citations