No sex please, we're mitochondria: a hypothesis on the somatic unit of inheritance of mammalian mtDNA

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses

1998 • 2,130 citations

Mitochondrial transcription factor A is necessary for mtDNA maintance and embryogenesis in mice

1998 • 1,517 citations

Replication of animal mitochondrial DNA

1982 • 1,221 citations

A Human Dynamin-related Protein Controls the Distribution of Mitochondria

1998 • 711 citations

Mitochondrial DNA molecules and virtual number of mitochondria per cell in mammalian cells

1988 • 637 citations

Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA

1996 • 580 citations

Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA.

1997 • 497 citations

Mammalian mitochondrial genetics: heredity, heteroplasmy and disease

1997 • 469 citations

Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos

1987 • 435 citations

Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

1997 • 388 citations

Organization of multiple nucleoids and DNA molecules in mitochondria of a human cell

1991 • 387 citations

The YTA10–12 Complex, an AAA Protease with Chaperone-like Activity in the Inner Membrane of Mitochondria

1996 • 312 citations

Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle

1977 • 304 citations

Assembly of cytochrome‐c oxidase in cultured human cells

1998 • 235 citations

Distinct genomic copy number in mitochondria of different mammalian organs

1990 • 231 citations

The HMG-1 box protein family: classification and functional relationships

1995 • 209 citations

The Division Apparatus of Plastids and Mitochondria

1998 • 203 citations

An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells

1991 • 198 citations

Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication.

1977 • 194 citations

MITOCHONDRIAL DYNAMICS IN YEAST

1998 • 185 citations

Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles.

1994 • 181 citations

The Yeast Dynamin-like Protein, Mgm1p, Functions on the Mitochondrial Outer Membrane to Mediate Mitochondrial Inheritance

1999 • 176 citations

Rolling circle replication of DNA in yeast mitochondria.

1991 • 164 citations

Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes: support for a genetic bottleneck.

1997 • 156 citations

Human mitochondria and mitochondrial genome function as a single dynamic cellular unit.

1994 • 142 citations

Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems

1995 • 132 citations

Functions of the High Mobility Group Protein, Abf2p, in Mitochondrial DNA Segregation, Recombination and Copy Number in Saccharomyces cerevisiae

1998 • 130 citations

Mitochondrial DNA mutation and the ageing process: bioenergy and pharmacological intervention

1992 • 128 citations

Analysis of mitochondrial DNA nucleoids in wild-type and a mutant strain of Saccharomyces cerevisiae that lacks the mitochondrial HMG box protein Abf2p

1996 • 113 citations

Complex I deficiency is Associated with 3243G:C Mitochondrial DNA in Osteosarcoma Cell Cybrids

1996 • 108 citations

Very Rare Complementation between Mitochondria Carrying Different Mitochondrial DNA Mutations Points to Intrinsic Genetic Autonomy of the Organelles in Cultured Human Cells

2000 • 97 citations

Mgm101p Is a Novel Component of the Mitochondrial Nucleoid That Binds DNA and Is Required for the Repair of Oxidatively Damaged Mitochondrial DNA

1999 • 95 citations

Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations

1999 • 93 citations

Aging-dependent Functional Alterations of Mitochondrial DNA (mtDNA) from Human Fibroblasts Transferred into mtDNA-less Cells

1996 • 90 citations

Comparison of the relative levels of the 3243 (A-->G) mtDNA mutation in heteroplasmic adult and fetal tissues.

1994 • 90 citations

Genotypic Stability, Segregation and Selection in Heteroplasmic Human Cell Lines Containing np 3243 Mutant mtDNA

2000 • 69 citations

The Nuclear ABC1 Gene is Essential for the Correct Conformation and Functioning of the Cytochrome bc₁ Complex and the Neighbouring Complexes II and IV in the Mitochondrial Respiratory Chain

1997 • 60 citations

5-Bromodeoxyuridine labeling of monomeric and catenated circular mitochondrial DNA in hela cells

1973 • 60 citations

Regulation of the expression of mitochondrial proteins: relationship between mtDNA copy number and cytochrome-c oxidase activity in human cells and tissues

1993 • 58 citations

Molecular and cellular mechanisms of mitochondrial nuclear division and mitochondriokinesis

1994 • 55 citations

Intracellular heteroplasmy for disease-associated point mutations in mtDNA: implications for disease expression and evidence for mitotic segregation of heteroplasmic units of mtDNA

1995 • 47 citations

Characterization of DNA-Binding Proteins Involved in the Assembly of Mitochondrial Nucleoids in the Yeast <italic>Saccharomyces cerevisiae</italic>

1995 • 46 citations

Threshold expression of the tRNALys A8344G mutation in single muscle fibres

1998 • 44 citations

The Interorganellar Interaction between Distinct Human Mitochondria with Deletion Mutant mtDNA from a Patient with Mitochondrial Disease and with HeLa mtDNA

1997 • 44 citations

Transcomplementation between Different Types of Respiration-deficient Mitochondria with Different Pathogenic Mutant Mitochondrial DNAs

1999 • 41 citations

Mitochondrial Gene Products

1987 • 37 citations

Characterization of DNA-protein complexes from the mitochondria of Xenopus laevis oocytes

1985 • 25 citations

DNA synthesis in isolated mitochondrial nucleoids from plasmodia ofPhysarum polycephalum

1998 • 21 citations

degSegregation of Mitochondrial DNAs Carrying a Pathogenic Point Mutation (tRNAleu3243) in Cybrid Cells

1995 • 18 citations

Fluorescence microscopy of DNA-protein structures from osmotically lysed mitochondria of yeast and tobacco

1998 • 6 citations