Immune Dynamics in the Pathogenesis of Human Lymphatic Filariasis

Re-assessing the global prevalence and distribution of lymphatic filariasis

1996 • 534 citations

The ICT Filariasis Test: A rapid-format antigen test for diagnosis of bancroftian filariasis

1997 • 446 citations

Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset.

1993 • 293 citations

Specific cellular immune unresponsiveness in human filariasis.

1977 • 238 citations

Immunological aspects of lymphatic filariasis and onchocerciasis in man

1984 • 210 citations

A highly specific and sensitive monoclonal antibody-based ELISA for the detection of circulating antigen in bancroftian filariasis.

1990 • 199 citations

Immunological tolerance: The key feature in human filariasis?

1991 • 192 citations

Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis.

1993 • 191 citations

T-cell activation and the balance of antibody isotypes in human lymphatic filariasis

1995 • 154 citations

A Monoclonal Antibody-Based Enzyme Immunoassay for Detecting Parasite Antigenemia in Bancroftian Filariasis

1987 • 147 citations

Regulation of the immune response in lymphatic filariasis and onchocerciasis

1991 • 138 citations

Immunopathology of lymphatic filariasis in man

1980 • 131 citations

Antigen-Specific Suppressor Cells and Suppressor Factors in Human Filariasis withBrugia malayi

1980 • 125 citations

Bacteriologic Studies of Skin, Tissue Fluid, Lymph, and Lymph Nodes in Patients with Filarial Lymphedema

1997 • 111 citations

Lymphoscintigraphic Analysis Of Lymphatic Abnormalities In Symptomatic And Asymptomatic Human Filariasis

1994 • 110 citations

The immunodeficient scid mouse as a model for human lymphatic filariasis.

1991 • 105 citations

FILARIASIS IN AMERICAN ARMED FORCES IN WORLD WAR II

1947 • 100 citations

Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state.

1992 • 98 citations

T Cell Responsiveness Correlates Differentially with Antibody Isotype Levels in Clinical and Asymptomatic Filariasis

1993 • 96 citations

Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis

1997 • 96 citations

Th1-like antifilarial immune responses predominate in antigen-negative persons

1996 • 85 citations

Ultrasonigraphic Evidence of Abnormal Lymphatic Vessels in Young Men with Adult Wuchereria Bancrofti Infection in the Scrotal Area

1996 • 85 citations

Transmission Intensity and Its Relationship to Infection and Disease Due toWuchereria bancroftiin Papua New Guinea

1997 • 84 citations

A comparison of the Og4C3 antigen capture ELISA, the Knott test, an IgG4 assay and clinical signs, in the diagnosis of Bancroftian filariasis.

1993 • 81 citations

Skin changes in filarial and non-filarial lymphoedema of the lower extremities.

1993 • 77 citations

A preliminary study of filariasis related acute adenolymphangitis with special reference to precipitating factors and treatment modalities.

1995 • 76 citations

Immunoepidemiology of lymphatic filariasis: the relationship between infection and disease

1991 • 69 citations

Clearance of Circulating Filarial Antigen as a Measure of the Macrofilaricidal Activity of Diethylcarbamazine in Wuchereria bancrofti Infection

1995 • 69 citations

Clinical, Parasitologic, And Immunologic Observations Of Patients With Hydrocele And Elephantiasis In An Area With Endemic Lymphatic Filariasis

1995 • 68 citations

The Epidemiology of Acute Adenolymphangitis Due to Lymphatic Filariasis in Northern Ghana

1996 • 67 citations

Elevated IL‐10 mRNA expression and downregulation of Th1‐type cytokines in microfilaraemic individuals with Wuchereria bancrofti infection

1997 • 65 citations

Stage-Specific Induction of Cytokines Regulates the Immune Response in Lymphatic Filariasis

1996 • 59 citations

The association between microfilaraemia and disease in lymphatic filariasis

1994 • 59 citations

A model for the dynamics of human lymphatic filariasis

1991 • 56 citations

The lymphatic pathology of Brugia pahangi in nude (athymic) and thymic mice C3H/HeN.

1984 • 52 citations

Heterogeneity in Filarial-Specific Immune Responsiveness among Patients with Lymphatic Obstruction

1993 • 51 citations

Endemic Filariasis on a Pacific Island

1982 • 50 citations

Elevated levels of T cell activation antigen CD27 and increased interleukin‐4 production in human lymphatic filariasis

1993 • 47 citations

Lymphatic filariasis: What mice can tell us

1996 • 44 citations

The Lymphatic Pathology of Brugia pahangi in Nude (Athymic) and Thymic Mice C3H/HeN

1984 • 41 citations

Histopathology of Brugia malayi-infected nude mice after immune-reconstitution

1991 • 41 citations

Abnormal Lymphatic Function in Presymptomatic Bancroftian Filariasis

1995 • 40 citations

Lymphatic abnormalities in human filariasis as depicted by lymphangioscintigraphy.

1993 • 39 citations

Specific T cell unresponsiveness in human filariasis: diversity in underlying mechanisms

1995 • 37 citations

Bancroftian lymphangitis in northeastern Brazil: a histopathological study of 17 cases.

1992 • 35 citations

Parasite antigenemia in lymphatic filariasis

1990 • 34 citations

Community diagnosis of Bancroftian filariasis

1993 • 30 citations

Differential Proliferative and Interleukin-10 Responses to Fractionated Filarial Antigens: Preferential Recognition by Patients with Chronic Lymphatic Dysfunction

1994 • 29 citations

The Presence or Absence of Active Infection, Not Clinical Status, Is Most Closely Associated with Cytokine Responses in Lymphatic Filariasis

1996 • 28 citations

Lymphatic Abnormalities in Human Filariasis as Depicted by Lymphangioscintigraphy

1993 • 25 citations

Very late antigen-4/vascular cell adhesion molecule-1 (VLA-4/VCAM-1) pathway is involved in the transendothelial migration of lymphocytes in bancroftian filariasis.

1996 • 24 citations

The lymphatic pathology of chronic Brugia pahangi infection in the dog

1989 • 24 citations

Predominant CD8+ infiltrate in limb biopsies of individuals with filarial lymphedema and elephantiasis.

1995 • 24 citations

Og4C3 circulating antigen, anti-Brugia malayi IgG and IgG4 titers in Wuchereria bancrofti infected patients, according to their parasitological status.

1994 • 22 citations

Lymphatic pathology in Wuchereria bancrofti microfilaraemic infections

1995 • 22 citations

Lymphatic Filariasis

1997 • 16 citations

Past exposure and the dynamics of lymphatic filariasis infection in young children

1996 • 9 citations

T-Lymphocytes from Individuals with Filarial Inflammatory Disease Have Increased Transendothelial Migrationin Vitro

1997 • 2 citations