Nucleotide sequence of a cloned cDNA corresponding to secreted μ chain of mouse immunoglobulin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

1977 • 2,233 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

Purification and Further Properties of Single‐Strand‐Specific Nuclease from Aspergillus oryzae

1973 • 862 citations

Codon catalog usage and the genome hypothesis

1980 • 772 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Stimulation by Cyclic Adenosine Monophosphate of Plasmid Deoxyribonucleic Acid Replication and Catabolite Repression of the Plasmid Deoxyribonucleic Acid-Protein Relaxation Complex

1973 • 505 citations

Amplification and characterization of a β-globin gene synthesized in vitro

1976 • 495 citations

Ovalbumin gene is split in chicken DNA

1977 • 396 citations

A general method for the purification of restriction enzymes

1978 • 314 citations

Deoxynucleotide-polymerizing Enzymes of Calf Thymus Gland

1971 • 306 citations

Polynucleotides. CXXIII. Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase

1973 • 293 citations

Polynucleotide kinase exchange reaction: quantitave assay for restriction endonuclease-generated 5'-phosphoroyl termini in DNA.

1977 • 289 citations

Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene

1979 • 230 citations

Complete sequence of constant and 3′ noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing

1978 • 211 citations

Recognition sequence of restriction endonuclease III from Hemophilus influenzae

1975 • 173 citations

[7] Terminal transferase-catalyzed addition of nucleotides to the 3′ termini of DNA

1980 • 164 citations

The isolation of plasmids containing dna complementary to messenger rna for variant surface glycoproteins of Trypanosoma brucei

1980 • 161 citations

Immunoglobulin messenger RNAs in murine cell lines that have characteristics of immature B lymphocytes

1979 • 158 citations

Detection of 5-methylcytosine in DNA sequences

1978 • 148 citations

Amino acid sequence of a mouse immunoglobulin mu chain.

1979 • 134 citations

Quantitative analysis of specific labelled RNA's using DNA covalently linked to diazobenzyloxy-methyl-paper

1979 • 87 citations

Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-γ 2a heavy chain

1980 • 81 citations

Nucleotide sequence of immunoglobulin heavy chain joining segments between translocated VH and mu constant regions genes.

1980 • 69 citations

Structure of the Constant and 3′ Untranslated Regions of the Murine γ2b Heavy Chain Messenger RNA

1979 • 66 citations

Mouse Cμ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains

1980 • 65 citations

Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.

1980 • 59 citations

The ovalbumin gene. In vitro enzymatic synthesis and characterization.

1976 • 59 citations

Isolation, purification, and properties of mouse heavy-chain immunoglobulin mRNAs

1978 • 56 citations

Sodium pyrophosphate inhibition of RNA.DNA hybrid degradation by reverse transcriptase.

1978 • 55 citations

Cloning and amplification of rabbit alpha- and beta-globin gene sequences into Escherichia coli plasmids.

1977 • 45 citations

Structure of the constant and 3′ untranslated regions of the murine Balb/c γ2a heavy chain messenger RNA

1980 • 44 citations

Nuclear Transcripts of Mouse Heavy Chain Immunoglobulin Genes Contain Only the Expressed Class of C-Region Sequences

1979 • 37 citations

Conservatism in the Evolution of Immunoglobulin

1972 • 29 citations

Mutual homology of mouse immunoglobulin .gamma.-chain gene sequences

1979 • 29 citations

A mouse immunoglobulin heavy chain deletion mutant: isolation of a cDNA clone and sequence analysis of the mRNA

1980 • 22 citations

The sequence at the 3' terminus of mouse immunoglobulin secreted mu chain messenger RNA determined from cloned cDNA.

1980 • 16 citations