Clinical pharmacology and therapeutic applications of the new oral angiotensin converting enzyme inhibitor, captopril

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

Antihypertensive Effect of the Oral Angiotensin Converting-Enzyme Inhibitor SQ 14225 in Man

1978 • 612 citations

Sustained Effectiveness of Converting-Enzyme Inhibition in Patients with Severe Congestive Heart Failure

1980 • 380 citations

Oral Angiotensin-Converting Enzyme Inhibitor in Long-Term Treatment of Hypertensive Patients

1979 • 357 citations

Captopril-induced Changes in Prostaglandin Production

1980 • 340 citations

A SPECIFIC ORALLY ACTIVE INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME IN MAN

1977 • 332 citations

Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor.

1980 • 291 citations

ICRF 159

1974 • 248 citations

Converting enzyme inhibition with an orally active compound in hypertensive man.

1979 • 224 citations

Reversal of Vascular and Renal Crises of Scleroderma by Oral Angiotensin-Converting-Enzyme Blockade

1979 • 210 citations

LONG-TERM EFFECTS OF CAPTOPRIL (SQ14 225) ON BLOOD-PRESSURE AND HORMONE LEVELS IN ESSENTIAL HYPERTENSION

1979 • 191 citations

Interruption of the renin-angiotensin system in hypertensive patients by captopril induces sustained reduction in aldosterone secretion, potassium retention and natruiresis.

1979 • 185 citations

Disposition of captopril in normal subjects

1980 • 161 citations

Discrepancy between antihypertensive effect and angiotensin converting enzyme inhibition by captopril.

1980 • 145 citations

The captopril-induced eruption. A possible mechanism: cutaneous kinin potentiation.

1980 • 133 citations

HEALTH VISITING AND GENERAL PRACTICE.

1964 • 120 citations

The Captopril-Induced Eruption

1980 • 104 citations

CAPTOPRIL-ASSOCIATED AGRANULOCYTOSIS

1980 • 101 citations

Proteinuria During Long-term Captopril Therapy

1980 • 101 citations

Hemodynamic and volume changes associated with captopril.

1980 • 98 citations

COMBINED TREATMENT OF SEVERE INTRACTABLE HYPERTENSION WITH CAPTOPRIL AND DIURETIC

1980 • 96 citations

INNAPPROPRIATE RENIN SECRETION UNMASKED BY CAPTOPRIL (SQ 14 225) IN HYPERTENSION OF CHRONIC RENAL FAILURE

1978 • 86 citations

Captopril-induced pemphigus.

1980 • 82 citations

FŒTAL AND NEO‐NATAL MORTALITY

1942 • 81 citations

Hemodynamic and antihypertensive effects of captopril, an orally active angiotensin converting enzyme inhibitor.

1979 • 78 citations

Resistant Hypertension: Diagnosis and Management

1978 • 78 citations

Captopril in severe treatment-resistant hypertension

1980 • 73 citations

Effect of Captopril on Renal Vascular Tone in Patients with Essential Hypertension

1979 • 64 citations

CAPTOPRIL: REVERSIBLE RENAL FAILURE WITH SEVERE HYPERKALÆMIA

1980 • 58 citations

Use of First-Dose Response or Plasma Renin Activity to Predict the Long-Term Effect of Captopril

1980 • 54 citations

CAPTOPRIL AND FRUSEMIDE IN SEVERE DRUG-RESISTANT HYPERTENSION

1980 • 53 citations

Acute and chronic systemic and pulmonary hemodynamic effects of angiotensin converting enzyme inhibition with captopril in hypertensive patients

1980 • 50 citations

Hemodialysis-Resistant Hypertension: Control with an Orally Active Inhibitor of Angiotensin-Converting Enzyme*

1979 • 49 citations

Constrasts and similarities of acute hemodynamic responses to specific antagonism of angiotensin II ([Sar1, Thr8] A II) and to inhibition of converting enzyme (captopril).

1980 • 48 citations

Effect of captopril (SQ 14225) on blood pressure, plasma renin activity and angiotensin I converting enzyme activity.

1979 • 46 citations

Captopril in Hypertension with Renal Artery Stenosis and in Intractable Hypertension; Acute and Chronic Changes in Circulating Concentrations of Renin, Angiotensins I and II and Aldosterone, and in Body Composition

1979 • 37 citations

Endocrine profile in the long-term phase of converting-enzyme inhibition

1980 • 35 citations

Endocrine and Cardiovascular Influences of Converting Enzyme Inhibition with SQ 14225 in Hypertensive Patients in the Supine Position and during Head-Up Tilt before and after Sodium Depletion*

1980 • 35 citations

The Measurement of Angiotensin-Converting Enzyme in Subjects Receiving Captopril

1980 • 35 citations

The alcoholic doctor. A case of neglect.

1975 • 34 citations

Captopril Treatment of Idiopathic Edema

1979 • 29 citations

Absence of blood-pressure lowering effect of captopril in anephric patients.

1980 • 27 citations

Captopril in Diuretic-Treated Hypertensive Patients

1980 • 19 citations

The Middlesex Smallpox Outbreak

1946 • 11 citations

Treatment of Drug-Resistant Hypertension with Minoxidil or Angiotensin-Converting Enzyme Inhibitor

1980 • 11 citations

Effects of captopril, diuretic, and their combination in low-renin essential hypertension

1980 • 7 citations

SPIROCHAETAL JAUNDICE IN A LONDON SEWER WORKER CONFIRMED BY LABORATORY EXAMINATIONS

1935 • 6 citations

Captopril in Refractory Malignant Hypertension

1980 • 2 citations