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1989 • 1,313 citations

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Subanesthetic Doses of Ketamine Stimulate Psychosis in Schizophrenia

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5-Hydroxytryptamine2 and 5-hydroxytryptamine1A receptors mediate opposing responses on membrane excitability in rat association cortex

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Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents

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Increased Serotonin2 and β-Adrenergic Receptor Binding in the Frontal Cortices of Suicide Victims

1986 • 552 citations

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5-Hydroxytryptamine _2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

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Positron Emission Tomography and Fluorodeoxyglucose Studies of Metabolic Hyperfrontality and Psychopathology in the Psilocybin Model of Psychosis

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Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG)

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Buprenorphine Treatment of Refractory Depression

1995 • 344 citations

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Repetitive Action Potentials in Isolated Nerve Terminals in the Presence of 4‐Aminopyridine: Effects on Cytosolic Free Ca²⁺ and Glutamate Release

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Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sites

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5-HT1A and 5-HT2A Receptor mRNAs and Binding Site Densities Are Differentially Altered in Schizophrenia

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5HT2 receptor changes in major depression

1990 • 261 citations

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Expression of Mu opioid receptor mRNA in rat brain: An in situ hybridization study at the single cell level

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Increased frontal and reduced parietal glucose metabolism in acute untreated schizophrenia

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1988 • 193 citations

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Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex: evidence for the involvement of a 5-HT2 -activated interneuron

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Mescaline-induced psychopathological, neuropsychological, and neurometabolic effects in normal subjects: Experimental psychosis as a tool for psychiatric research

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Serotonin Receptors in Suicide Victims with Major Depression

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Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis.

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LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex.

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Calcium-Dependent Paired-Pulse Facilitation of Miniature EPSC Frequency Accompanies Depression of EPSCs at Hippocampal Synapses in Culture

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Excitatory responses to serotonin (5‐HT) in neurons of the rat piriform cortex: Evidence for mediation by 5‐HT_1C receptors in pyramidal cells and 5‐HT₂ receptors in interneurons

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Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the ‘atypical’ antipsychotics, clozapine and risperidone

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Three clinical syndromes of schizophrenia in untreated subjects: relation to brain glucose activity measured by position emission tomography (PET)

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A comparison of trazodone and fluoxetine: implications for a serotonergic mechanis of antidepressant action

1992 • 115 citations

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Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: Antagonism by atypical antipsychotic drugs

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Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5-HT2 binding affinity

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Protein kinase C inhibitors enhance the 5‐HT_2A receptor‐mediated excitatory effects of serotonin on interneurons in rat piriform cortex

1995 • 18 citations