Glial cell line derived neurotrophic factor promotes the recovery of dopamine neurons damaged by 6-hydroxydopamine in vitro

GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF

1996 • 1,170 citations

Characterization of a multicomponent receptor for GDNF

1996 • 1,086 citations

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1995 • 1,084 citations

Functional recovery in parkinsonian monkeys treated with GDNF

1996 • 955 citations

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

1974 • 894 citations

Functional receptor for GDNF encoded by the c-ret proto-oncogene

1996 • 795 citations

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1995 • 659 citations

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1995 • 593 citations

Distinct Mechanisms Underlie Neurotoxin-Mediated Cell Death in Cultured Dopaminergic Neurons

1999 • 393 citations

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion.

1995 • 377 citations

GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo

1995 • 374 citations

Short-Term GDNF Treatment Provides Long-Term Rescue of Lesioned Nigral Dopaminergic Neurons in a Rat Model of Parkinson’s Disease

1996 • 258 citations

<scp>l</scp>‐DOPA Up‐Regulates Glutathione and Protects Mesencephalic Cultures Against Oxidative Stress

1996 • 184 citations

Glial Cell Line‐Derived Neurotrophic Factor Exerts Neurotrophic Effects on Dopaminergic Neurons In Vitro and Promotes Their Survival and Regrowth After Damage by 1‐Methyl‐4‐Phenylpyridinium

1996 • 181 citations

Glial Cell Line-derived Neurotrophic Factor Signals through the RET Receptor and Activates Mitogen-activated Protein Kinase

1996 • 168 citations

GDNF Protection against 6-OHDA: Time Dependence and Requirement for Protein Synthesis

1997 • 128 citations

GDNF reduces apoptosis in dopaminergic neurons in vitro

1995 • 99 citations

Basic Fibroblast Growth Factor Stimulation of Glial Cells Protects Dopamine Neurons from 6‐Hydroxydopamine Toxicity: Involvement of the Glutathione System

1997 • 94 citations

1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Metabolism and l‐Methyl‐4‐Phenylpyridinium Uptake in Dissociated Cell Cultures from the Embryonic Mesencephalon

1988 • 55 citations

Competitive irreversible inhibition of dopamine uptake by 6-hydroxydopamine.

1993 • 52 citations