Kinetics and mechanism of the interaction of Escherichia coli RNA polymerase with the λPR promoter

Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

1978 • 1,651 citations

Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory

1981 • 1,271 citations

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

1975 • 1,157 citations

Ion effects on ligand-nucleic acid interactions

1976 • 1,016 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

[16] Plasmids of Escherichia coli as cloning vectors

1979 • 655 citations

PROTEIN-NUCLEIC ACID INTERACTIONS IN TRANSCRIPTION: A Molecular Analysis

1984 • 620 citations

Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor-operator interaction: kinetic measurements and conclusions

1981 • 579 citations

Escherichia colipromoter sequences predictin vitroRNA polymerase selectivity

1984 • 492 citations

Studies of the binding of Escherichia coli RNA polymerase to DNA

1972 • 459 citations

[45] The use of intensifying screens or organic scintillators for visualizing radioactive molecules resolved by gel electrophoresis

1980 • 367 citations

A restriction map of the bacteriophage T4 genome

1980 • 326 citations

Purification and properties of the .sigma. subunit of Escherichia coli DNA-dependent RNA polymerase

1979 • 319 citations

A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes

1982 • 264 citations

Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction

1977 • 251 citations

Polyelectrolyte Theories and their Applications to DNA

1982 • 234 citations

A quantitative assay for bacterial RNA polymerases.

1979 • 216 citations

Mechanism of activation of transcription initiation from the λPRM promoter

1982 • 210 citations

Double Helical DNA: Conformations, Physical Properties, and Interactions with Ligands

1981 • 201 citations

Promoters: Structure and function

1983 • 186 citations

Nonspecific interactions of Escherichia coli RNA polymerase with native and denatured DNA: differences in the binding behavior of core and holoenzyme

1978 • 163 citations

Interaction of RNA Polymerase with Promoters from Bacteriophage fd

1977 • 156 citations

Studies of Ribonucleic Acid Chain Initiation by Escherichia coli Ribonucleic Acid Polymerase Bound to T7 Deoxyribonucleic Acid

1974 • 113 citations

Salt dependence of the kinetics of the lac repressor-operator interaction: role of nonoperator deoxyribonucleic acid (DNA) in the association reaction

1981 • 110 citations

Binding of Escherichia coli RNA polymerase to T7 DNA. Displacement of holoenzyme from promoter complexes by heparin.

1977 • 91 citations

Analysis of ion concentration effects on the kinetics of protein-nucleic acid interactions

1978 • 89 citations

Biochemistry of Metabolic Processes

1983 • 83 citations

Rapid and simple removal of contaminating RNA from plasmid DNA without the use of RNase

1981 • 82 citations

Binding of Escherichia coli RNA polymerase holoenzyme to bacteriophage T7 DNA

1982 • 74 citations

Association kinetics with coupled diffusion

1978 • 71 citations

Characterization of ribonucleic acid polymerase-T7 promoter binary complexes

1980 • 70 citations

Binding of Escherichia coli RNA polymerase holoenzyme to bacteriophage T7 DNA

1982 • 68 citations

Kinetics and mechanism of the association of the bacteriophage T4 gene 32 (helix destabilizing) protein with single-stranded nucleic acids

1981 • 66 citations

Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: evaluation of promoter binding constants as a function of solution conditions

1980 • 62 citations

High resolution electron microscopic studies of genetic regulation

1976 • 61 citations

Physicochemical studies on interactions between DNA and RNA polymerase. Ultraviolet absorption measurements

1978 • 58 citations

A Study of Unwinding of DNA and Shielding of the DNA Grooves by RNA Polymerase by Using Methylation with Dimethylsulphate

1978 • 57 citations

Direct evidence for the preferential binding of Escherichia coli RNA polymerase holoenzyme to the ends of deoxyribonucleic acid restriction fragments

1983 • 56 citations

Aggregation equilibria of Escherichia coli RNA polymerase: evidence for anion-linked conformational transitions in the protomers of core and holoenzyme

1982 • 53 citations

Nitrocellulose filter binding studies of the interactions of Escherichia coli RNA polymerase holoenzyme with deoxyribonucleic acid restriction fragments: evidence for multiple classes of nonpromoter interactions, some of which display promoter-like properties

1982 • 53 citations

Escherichia coli RNA polymerase binding and initiation of transcription on fragments of Λrifd18 DNA containing promoters for Λ genes and for rrnB, tufB, rplK,A, rplJ,L, and rpoB,C genes

1979 • 50 citations

Mutation-induced changes in RNA polymerase-lac ps promoter interactions.

1982 • 46 citations

Kinetic investigation of the mechanism of RNA polymerase binding to mutant lac promoters.

1980 • 40 citations

Electron Microscopy Analysis of the Interaction between Escherichia coli DNA-Dependent RNA Polymerase and the Replicative Form of Phage fd DNA. 2. Analysis of the Dissociation Kinetics

1977 • 35 citations

Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: selectivity exists over a wide range of solution conditions

1980 • 34 citations

Electron Microscopy Analysis of the Interaction between Escherichia coli DNA-Dependent RNA Polymerase and the Replicative Form of Phage fd DNA. 1. Mapping of the Binding Sites

1977 • 34 citations

On the promoter complex formation rate of E.coli RNA polymerases with T7 phage DNA

1980 • 29 citations

Mechanism of ribonucleic acid chain initiation. Molecular pulse-labeling study of ribonucleic acid synthesis on T7 deoxyribonucleic acid template

1981 • 20 citations

Differential binding of RNA polymerase to the pRM and pR promoters of bacteriophage lambda

1983 • 10 citations

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