Gender, Sex Steroids, Corticotropin-Releasing Factor, Nitric Oxide, and the HPA Response to Stress

Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study

1990 • 2,107 citations

Gonadal Steroid Hormone Receptors and Sex Differences in the Hypothalamo-Pituitary-Adrenal Axis

1994 • 781 citations

Prenatal Stress Induces High Anxiety and Postnatal Handling Induces Low Anxiety in Adult Offspring: Correlation with Stress-Induced Corticosterone Secretion

1997 • 768 citations

Variations in the Hypothalamic-Pituitary-Adrenal Response to Stress during the Estrous Cycle in the Rat

1991 • 664 citations

Vasopressinergic Control of Pituitary Adrenocorticotropin Secretion Comes of Age

1993 • 651 citations

Effects of Synthetic Ovine Corticotropin-Releasing Factor, Glucocorticoids, Catecholamines, Neurohypophysial Peptides, and Other Substances on Cultured Corticotropic Cells*

1983 • 567 citations

Expression and neuropeptidergic characterization of estrogen receptors (ER? and ER?) throughout the rat brain: Anatomical evidence of distinct roles of each subtype

1998 • 565 citations

Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin

1983 • 535 citations

Differential regulation of corticotropin-releasing factor mRNA in rat brain regions by glucocorticoids and stress

1991 • 434 citations

Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimophism of the stress response and immune/inflammatory reaction.

1993 • 424 citations

Interaction of Corticotropin-Releasing Factor and Arginine Vasopressin on Adrenocorticotropin Secretionin Vivo*

1983 • 406 citations

Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal system in the female rat

1992 • 404 citations

Circadian Variation in Basal Plasma Corticosterone and Adrenocorticotropin in the Rat: Sexual Dimorphism and Changes across the Estrous Cycle*

1997 • 397 citations

Possible underlying mechanisms of sexual dimorphism in the immune response, fact and hypothesis

1989 • 346 citations

The inhibitory effect of testosterone on hypothalamic-pituitary-adrenal responses to stress is mediated by the medial preoptic area

1996 • 336 citations

Corticotropin-Releasing Factor*

1982 • 326 citations

Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and foot shock stressors

1994 • 325 citations

Chapter 12 The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress

1996 • 323 citations

Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF).

1984 • 322 citations

Maternal Deprivation Effect on the Infant’s Neural Stress Markers Is Reversed by Tactile Stimulation and Feeding But Not by Suppressing Corticosterone

1998 • 284 citations

Inhibition of Adrenocorticotropic Hormone Secretion in the Rat by Immunoneutralization of Corticotropin-Releasing Factor

1982 • 269 citations

Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.

1995 • 230 citations

In the rat, endogenous nitric oxide modulates the response of the hypothalamic-pituitary-adrenal axis to interleukin-1 beta, vasopressin, and oxytocin

1994 • 222 citations

Differential colocalization of estrogen receptor β (ERβ) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: An immunocytochemical study

1998 • 220 citations

Adrenal Sensitivity to Adrenocorticotropin Varies Diurnally*

1981 • 209 citations

Cytokines Act within the Brain to Inhibit Luteinizing Hormone Secretion and Ovulation in the Rat*

1990 • 205 citations

Hypothalamic effector neurons and extended circuitries activated in ?neurogenic? stress: A comparison of footshock effects exerted acutely, chronically, and in animals with controlled glucocorticoid levels

1998 • 202 citations

Alcohol Stimulates ACTH Secretion in the Rat: Mechanisms of Action and Interactions with Other Stimuli

1996 • 191 citations

Studies of the Nature of the Interaction between Vasopressin and Corticotropin-Releasing Factor on Adrenocorticotropin Release in the Rat*

1984 • 160 citations

Androgen Inhibits the Increases in Hypothalamic Corticotropin-Releasing Hormone (CRH) and CRH-lmmunoreactivity following Gonadectomy

1994 • 152 citations

Female Rats Release More Corticosterone Than Males in Response to Alcohol: Influence of Circulating Sex Steroids and Possible Consequences for Blood Alcohol Levels

1993 • 148 citations

Prenatal immune challenge alters the hypothalamic-pituitary-adrenocortical axis in adult rats.

1994 • 145 citations

Corticotropin releasing hormone mRNA is elevated on the afternoon of proestrus in the parvocellular paraventricular nuclei of the female rat

1990 • 136 citations

The Impact of Physiological Stimuli on the Expression of Corticotropin-Releasing Hormone (CRH) and Other Neuropeptide Genes

1996 • 128 citations

Effects of gonadectomy and sex hormone therapy on the endotoxin-stimulated hypothalamo-pituitary-adrenal axis: evidence for a neuroendocrine-immunological sexual dimorphism.

1992 • 126 citations

Fast Glucocorticoid Feedback Inhibition of ACTH Secretion in the Ovariectomized Rat: Effect of Chronic Estrogen and Progesterone

1994 • 113 citations

Influence of Immune Signals on the Hypothalamic-Pituitary Axis of the Rodent

1995 • 112 citations

Prenatal ethanol effects: Sex differences in offspring stress responsiveness

1992 • 110 citations

Circadian Variation in Basal Plasma Corticosterone and Adrenocorticotropin in the Rat: Sexual Dimorphism and Changes across the Estrous Cycle

1997 • 101 citations

Changes in Plasma Adrenocorticotropin, Corticosterone, Corticosteroid‐Binding Globulin, and Hippocampal Glucocorticoid Receptor Occupancy/Translocation in Rat Pups in Response to Stress

1996 • 97 citations

Cellular mechanisms underlying the development and expression of individual differences in the hypothalamic-pituitary-adrenal stress response

1991 • 92 citations

Alanine series of ovine corticotropin releasing factor (oCRF): a structure-activity relationship study

1992 • 91 citations

Interaction between Ethanol and Stress on ACTH and β‐Endorphin Secretion

1988 • 79 citations

Estrogen-Induced Alterations in the Regulation of Mineralocorticoid and Glucocorticoid Receptor Messenger RNA Expression in the Female Rat Anterior Pituitary Gland and Brain

1993 • 75 citations

Divergence in the Expression of Molecular Markers of Neuronal Activation in the Parvocellular Paraventricular Nucleus of the Hypothalamus Evoked by Alcohol Administration via Different Routes

1998 • 71 citations

Median eminence corticotrophin-releasing hormone content following prenatal stress and neonatal handling

1996 • 70 citations

Stimulatory effect of interleukin-1β on the hypothalamic-pituitary-adrenal axis of the rat: influence of age, gender and circulating sex steroids

1994 • 67 citations

Alcohol increases the expression of type 1, but not type 2α corticotropin-releasing factor (CRF) receptor messenger ribonucleic acid in the rat hypothalamus

1997 • 64 citations

Sex Differences in the Hypothalamo-Pituitary-Adrenal Axis Response to Inflammatory and Neuroendocrine Stressors

1994 • 62 citations

Urocortin Is Not a Significant Regulator of Intermittent Electrofootshock-Induced Adrenocorticotropin Secretion in the Intact Male Rat**This work was supported by NIH Grant DK-26741 and The Foundation for Research.

1999 • 59 citations

Cytokines in the Nervous System

1996 • 55 citations

DIFFERENTIAL EFFECTS OF NEONATAL HANDLING ON ANXIETY, CORTICOSTERONE RESPONSE TO STRESS, AND HIPPOCAMPAL GLUCOCORTICOID AND SEROTONIN (5-HT)2A RECEPTORS IN LEWIS RATS

1998 • 53 citations

Sex differences in hypothalamic-pituitary-adrenal responding to endotoxin challenge in the neonate: reversal by gonadectomy

1994 • 51 citations

Familial density of alcoholism: effects on psychophysiological responses to ethanol

1991 • 48 citations

Sexual dimorphism in regulation of type II corticosteroid receptor immunoreactivity in the rat hippocampus.

1992 • 47 citations

Influence of nitric oxide synthase inhibitors on the ACTH and cytokine responses to peripheral immune signals.

1998 • 47 citations

Influence of Carbon Monoxide, and its Interaction with Nitric Oxide, on the Adrenocorticotropin Hormone Response of the Normal Rat to a Physico‐Emotional Stress

1998 • 41 citations

Estradiol or ovariectomy decreases crf synthesis in hypothalamus

1989 • 39 citations

Astressin Analogues (Corticotropin-Releasing Factor Antagonists) with Extended Duration of Action in the Rat

1998 • 38 citations

Effects of gonadectomy and sex hormone therapy on the endotoxin- stimulated hypothalamo-pituitary-adrenal axis: evidence for a neuroendocrine-immunological sexual dimorphism

1992 • 36 citations

Sex difference in glucocorticoid regulation of vasopressin mRNA in the paraventricular hypothalamic nucleus.

1997 • 31 citations

Urocortin Is Not a Significant Regulator of Intermittent Electrofootshock-Induced Adrenocorticotropin Secretion in the Intact Male Rat

1999 • 29 citations

Selective inhibitors of nitric oxide synthase (NOS) implicate a constitutive isoform of NOS in the regulation of interleukin-1-induced ACTH secretion in rats

1996 • 26 citations

Acute stress- or lipopolysaccharide-induced corticosterone secretion in female rats is independent of the oestrous cycle

1994 • 25 citations

Estrogens decrease expression of the corticotropin-releasing factor gene in the hypothalamic paraventricular nucleus and of the proopiomelanocortin gene in the anterior pituitary of ovariectomized rats

1995 • 17 citations

Constrained Corticotropin-Releasing Factor (CRF) Agonists and Antagonists withi−(i+3) G<u>lu-Xaa-<scp>d</scp>Xbb-Ly</u>s Bridges

1998 • 16 citations

Sexual dimorphism in regulation of type II corticosteroid receptor immunoreactivity in the rat hippocampus

1992 • 13 citations

Sex Steroid Regulation of the Hypothalamo-Pituitary-Adrenal Axis Activity in Middle-Aged Mice during Endotoxic Shock

1994 • 12 citations

Cytokine Effects on Neuroendocrine Axes: Influence of Nitric Oxide and Carbon Monoxide

1996 • 9 citations