Age at Onset and Causes of Disease

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

Aging, Natural Death, and the Compression of Morbidity

1980 • 3,304 citations

How People Make Their Own Environments: A Theory of Genotype Environment Effects

1983 • 2,778 citations

THE CONTRIBUTION OF THE SOCIAL ENVIRONMENT TO HOST RESISTANCE: THE FOURTH WADE HAMPTON FROST LECTURE1

1995 • 1,996 citations

THE CONTRIBUTION OF THE SOCIAL ENVIRONMENT TO HOST RESISTANCE1

1976 • 1,731 citations

The Genetics of Human Populations.

1972 • 1,645 citations

The inheritance of liability to certain diseases, estimated from the incidence among relatives

1965 • 1,618 citations

INEQUALITIES IN DEATH—SPECIFIC EXPLANATIONS OF A GENERAL PATTERN?

1984 • 1,467 citations

Handbook of the Biology of Aging

1990 • 1,219 citations

THE NATURAL HISTORY OF SYSTEMIC LUPUS ERYTHEMATOSUS BY PROSPECTIVE ANALYSIS

1971 • 960 citations

Cultural transmission and evolution

1981 • 874 citations

Epidemiology of Diabetes and Its Vascular Lesions.

1979 • 559 citations

Dementia of the Alzheimer Type

1980 • 518 citations

Similarities of genetic (spontaneous) hypertension. Man and rat.

1981 • 511 citations

Epidemiology of gout and hyperuricemia

1967 • 490 citations

EPIDEMIOLOGY OF RHEUMATIC DISEASES

2006 • 458 citations

Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.

1983 • 456 citations

Dementia of the Alzheimer Type

1981 • 451 citations

Handbook of Teratology

1977 • 427 citations

Neurochemical characteristics of early and late onset types of Alzheimer's disease.

1984 • 411 citations

THE EPIDEMIOLOGY OF RHEUMATOID ARTHRITIS IN ROCHESTER MINNESOTA: A STUDY OF INCIDENCE, PREVALENCE, AND MORTALITY1

1980 • 400 citations

Studies of twins with systemic lupus erythematosus

1975 • 382 citations

Parkinson's disease in 65 pairs of twins and in a set of quadruplets

1983 • 353 citations

Epidemiology of parkinsonism: Incidence, classification, and mortality

1984 • 334 citations

Onset of Major Depression in Early Adulthood

1984 • 324 citations

Genetics of Common Disorders

1969 • 297 citations

The Genetics of Diabetes Mellitus

1970 • 276 citations

Studies in developmental neurobiology

1983 • 263 citations

Aging, Natural Death, and the Compression of Morbidity: Another View

1983 • 244 citations

Inherited deficiency of the second component of complement. Rheumatic disease associations.

1976 • 238 citations

Alzheimer's disease: Choline acetyltransferase activity in brain tissue from clinical and pathological subgroups

1983 • 223 citations

Diabetes Mellitus: Incidence, Prevalence, Survivorship, and Causes of Death in Rochester, Minnesota, 1945–1970

1976 • 217 citations

Cause of death in very old people.

1982 • 204 citations

Disability trends in the United States population 1966-76: analysis of reported causes.

1981 • 202 citations

EPIDEMIOLOGY of PARKINSON'S DISEASE IN FINLAND

1976 • 196 citations

Genetics of immunoresponsiveness to natural antigens in the mouse.

1979 • 191 citations

HLA-DR phenotypes in Spanish coeliac children: their contribution to the understanding of the genetics of the disease.

1983 • 182 citations

Strength and Weakness of the Genetic Approach to the Development of the Nervous System

1981 • 177 citations

Dynamics of Health Changes in the Oldest Old: New Perspectives and Evidence

1985 • 175 citations

Systemic lupus erythematosus in childhood. Analysis of 42 cases, with comparative data on 200 adult cases followed concurrently.

1968 • 173 citations

Is coeliac disease underdiagnosed?

1980 • 164 citations

Peptic Ulcer: A profile

1964 • 141 citations

Genetic epidemiology of coronary heart disease. Past, present, and future.

1984 • 140 citations

A family study of Paget's disease of bone.

1983 • 134 citations

Diabetes mellitus in the Pima Indians: Genetic and evolutionary considerations

1983 • 132 citations

The effect of Mendelian disease on human health: A measurement

1985 • 130 citations

Alzheimer's disease and senile dementia of Alzheimer type

1982 • 125 citations

Familial Aspects Of Inflammatory Bowel Disease

1971 • 119 citations

The Incidence of Duodenal Ulcer in Copenhagen County

1975 • 115 citations

The clinical spectrum of systemic lupus erythematosus in childhood.

1977 • 115 citations

Epidemiology of Parkinson's Disease in a Japanese City

1983 • 113 citations

Mortality in Crohn's disease

1981 • 113 citations

The Epidemiology of dementia

1981 • 112 citations

Refractory duodenal ulcer.

1984 • 112 citations

Epidemiological aspects of Crohn's disease: a review of the literature.

1984 • 103 citations

GENETICS OF HLA DISEASE ASSOCIATION

1981 • 98 citations

PARKINSON'S DISEASE

1973 • 95 citations

A clinical study of older age rheumatoid arthritis with comparison to a younger onset group.

1983 • 94 citations

THE FAMILIAL AGGREGATION OF RHEUMATOID ARTHRITIS AND ITS RELATIONSHIP TO THE HLA-DR4 ASSOCIATION

1984 • 88 citations

Severe systemic lupus erythematosus with nephritis in a boy with deficiency of the fourth component of complement

1977 • 87 citations

Diabetes in the elderly — a neglected area?

1984 • 81 citations

Peptic Ulcer in Massachusetts Physicians

1969 • 77 citations

Gout in a New England town. A prevalence study in Sudbury, Massachusetts.

1972 • 72 citations

Systemic lupus erythematosus in hereditary deficiency of the fourth component of complement

1982 • 71 citations

Diabetes mellitus and obesity

1973 • 71 citations

PAGET'S DISEASE OF BONE

1957 • 70 citations

Diabetes in Epidemiological Perspective

1983 • 69 citations

The association between rheumatoid arthritis and the HLA antigen DR4.

1983 • 64 citations

Factors Influencing the Course and Prognosis of Systemic Lupus Erythematosus

1959 • 63 citations

Studies on the genetic heterogeneity of diabetes mellitus

1971 • 63 citations

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease

1983 • 61 citations

Lupus in childhood.

1982 • 60 citations

HLA-DR3 and DR7 in coeliac disease: immunogenetic and clinical aspects.

1983 • 60 citations

THE EFFECT OF SEX AND PARITY ON THE INCIDENCE OF DIABETES MELLITUS<sup>1</sup>

1961 • 57 citations

Peptic Ulcer in Children

1961 • 54 citations

Incidence of Diabetes Mellitus in Oslo, Norway 1925 to 1954: Report No. 11 of the Life Insurance Companies' Institute for Medical Statistics at the Oslo City Hospitals

1966 • 52 citations

HLA antigens in systemic lupus erythematosus: relationship to disease severity, age at onset, and sex.

1984 • 51 citations

Duodenal Ulcer in Children

1972 • 51 citations

HLA antigens and seronegative rheumatoid arthritis.

1985 • 51 citations

The recent decline in mortality of the extreme aged: an analysis of statistical data.

1980 • 51 citations

Duodenal ulcer in childhood. A study of predisposing factors.

1968 • 50 citations

Incidence of diabetes mellitus in Oslo, Norway 1956-65

1977 • 50 citations

Mortality in Crohn's Disease

1980 • 49 citations

Duodenal ulcers: early and late onset.

1976 • 48 citations

Some unusual features of gouty arthritis in females

1977 • 47 citations

Teratogenic effects of environmental chemicals.

1977 • 47 citations

The effect of Mendelian disease on human health. II: Response to treatment

1985 • 46 citations

A defense of path analysis in genetic epidemiology.

1983 • 46 citations

Diversity of clinical features in gouty arthritis

1984 • 45 citations

Crohn's disease

1972 • 45 citations

Health and Disease among the Oldest Old: A Clinical Perspective

1985 • 44 citations

The William Allan Memorial Award Address: evolution of a palatable multifactorial threshold model.

1980 • 43 citations

Result of chronic levodopa therapy and its modification by bromocriptine in Parkinson's disease

2009 • 40 citations

DUODENAL ULCER IN CHILDHOOD

1968 • 39 citations

Relation of Animal Studies to the Problem in Man

1977 • 39 citations

Homozygous C2 deficiency with fulminant lupus erythematosus. severe nephritis via the alternative complement pathway

1978 • 36 citations

Thinking in one dimension: The impact of molecular biology on development

1985 • 36 citations

On "Path analysis in genetic epidemiology: a critique".

1983 • 35 citations

Similar prevalence of coeliac disease in children and middle-aged adults in a district of Sweden.

1983 • 33 citations

Epidemiology of rheumatic disorders in the pacific with particular emphasis on hyperuricaemia and gout

1981 • 30 citations

The Incidence of Gastric Ulcer and Duodenal Ulcer in North Norway

1985 • 30 citations

Peptic ulcer in twins. A study in personality, heredity, and environment.

1968 • 25 citations

An immunogenetic study of older age onset rheumatoid arthritis.

1984 • 25 citations

Identification of Two Subgroups of Familial Early-Onset Duodenal Ulcers

1980 • 21 citations

HLA-DR typing in coeliac disease: evidence for genetic heterogeneity.

1984 • 19 citations

Dementia associated with Parkinson's disease: a genetic study.

1980 • 18 citations

Prevalence of rheumatoid arthritis in families.

1972 • 17 citations

Inflammatory Disease of the Bowel

1980 • 16 citations

The value of investigations of the incidence of peptic ulcer in the families of patients with duodenal ulcer.

1972 • 13 citations

The Genetics of Peptic Ulcer

1985 • 11 citations