Effector region of the translation elongation factor EF-Tu.GTP complex stabilizes an orthoester acid intermediate structure of aminoacyl-tRNA in a ternary complex.

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours

1989 • 1,405 citations

Two G Protein Oncogenes in Human Endocrine Tumors

1990 • 1,038 citations

Intermediate states in the movement of transfer RNA in the ribosome

1989 • 736 citations

Crystal structure of active elongation factor Tu reveals major domain rearrangements

1993 • 533 citations

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

1990 • 489 citations

5′–3′ Exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis

1988 • 336 citations

Site of aminoacylation of tRNAs from Escherichia coli with respect to the 2'- or 3'-hydroxyl group of the terminal adenosine.

1975 • 147 citations

Effect of Kirromycin on Elongation Factor Tu. Location of the Catalytic Center for Ribosome . Elongation-Factor-Tu GTPase Activity on the Elongation Factor

1977 • 142 citations

Toward a Model for the Interaction Between Elongation Factor Tu and the Ribosome

1993 • 117 citations

How does the switch II region of G‐domains work?

1993 • 80 citations

Transacylation rates of aminoacyladenosine moiety at the 3'-terminus of aminoacyl-transfer ribonucleic acid

1983 • 69 citations

The reaction of ribosomes with elongation factor Tu.GTP complexes. Aminoacyl-tRNA-independent reactions in the elongation cycle determine the accuracy of protein synthesis.

1986 • 65 citations

Inactivation of Tu Factor-Guanosine Triphosphate Recognition and Ribosome-binding Ability by Terminal Oxidation-Reduction of Yeast Phenylalanine Transfer Ribonucleic Acid

1972 • 63 citations

Accepting Site for Aminoacylation of tRNAPhe from Yeast

1973 • 61 citations

The elongation factor Tu binds aminoacyl-tRNA in the presence of GDP.

1982 • 59 citations

Interaction of elongation factor‐Tu from Escherichia coli with aminoacyl‐tRNA carrying a fluorescent reporter group on the 3′ terminus

1989 • 44 citations

Specificity of Elongation Factor Tu from Escherichia coli with Respect to Attachment of the Amino Acid to the 2' or 3'-Hydroxyl Group of the Terminal Adenosine of tRNA

1977 • 39 citations

N‐tosyl‐L‐phenylalanylchloromethane reacts with cysteine 81 in the molecule of elongation factor Tu from Escherichia coli

1982 • 38 citations

Nucleotide binding and GTP hydrolysis by elongation factor Tu from Thermus thermophilus as monitored by proton NMR

1992 • 34 citations

Activity of the 2' and 3' isomers of aminoacyl-tRNA in the in vitro peptide elongation on E. coli ribosomes

1982 • 34 citations

Inhibition of ribosomal translocation by peptidyl-tRNA analogs

1983 • 25 citations

Slow transacylation of peptidyladenosine allows analysis of the 2'/3'-isomer specificity of peptidyltransferase

1985 • 23 citations

Overproduction of the Thermus thermophilus elongation factor Tu in Escherichia coli

1991 • 21 citations

Isomeric aminoacyl-tRNAs are both bound by elongation factor Tu.

1977 • 20 citations

Complete nuclear magnetic resonance signal assignments and initial structural studies of [13C]methyl-enriched yeast transfer ribonucleic acid

1983 • 19 citations

Aminoacyl-tRNA Exclusively in the 3′-Isomeric Form Is Bound to Polypeptide Chain Elongation Factor Tu1

1985 • 14 citations