Chronic Venous Insufficiency and Venous Ulceration

Detection of Deep-Vein Thrombosis by Real-Time B-Mode Ultrasonography

1989 • 883 citations

Chronic ulceration of the leg: extent of the problem and provision of care.

1985 • 740 citations

Clinical evaluation of recombinant human platelet – derived growth factor for the treatment of lower extremity diabetic ulcers

1995 • 616 citations

Causes of venous ulceration: a new hypothesis

1988 • 560 citations

Venous Thromboembolism and Other Venous Disease in the Tecumseh Community Health Study

1973 • 539 citations

Leg ulcers: Epidemiology and aetiology

1986 • 472 citations

Topical Antimicrobial Toxicity

1985 • 467 citations

Epidemiology of chronic venous ulcers

1991 • 415 citations

Chronic ulcer of the leg: clinical history.

1987 • 390 citations

Platelet-derived growth factor BB for the treatment of chronic pressure ulcers

1992 • 389 citations

Relationship between changes in the deep venous system and the development of the postthrombotic syndrome after an acute episode of lower limb deep vein thrombosis: A one- to six-year follow-up

1995 • 389 citations

Sustained compression and healing of chronic venous ulcers.

1988 • 370 citations

Pericapillary fibrin in the ulcer-bearing skin of the leg: the cause of lipodermatosclerosis and venous ulceration.

1982 • 350 citations

Long-term Sequelae of Acute Venous Thrombosis

1983 • 346 citations

Classification and grading of chronic venous disease in the lower limbs. A consensus statement

1996 • 301 citations

Risk factors for chronic venous insufficiency: A dual case-control study

1995 • 298 citations

The socioeconomic effects of an iliofemoral venous thrombosis

1977 • 287 citations

Superficial venous insufficiency: Correlation of anatomic extent of reflux with clinical symptoms and signs

1994 • 281 citations

Fifteen-year results of ambulatory compression therapy for chronic venous ulcers.

1991 • 259 citations

Topical Use of Human Recombinant Epidermal Growth Factor (h‐EGF) in Venous Ulcers

1992 • 226 citations

Effect of Topical Basic Fibroblast Growth Factor on the Healing of Chronic Diabetic Neuropathic Ulcer of the foot: A pilot, randomized, double-blind, placebo-controlled study

1995 • 219 citations

Venous reflux: Quantification and correlation with the clinical severity of chronic venous disease

1988 • 214 citations

Distribution of valvular incompetence in patients with venous stasis ulceration

1991 • 213 citations

Venous lipodermatosclerosis: treatment by fibrinolytic enhancement and elastic compression.

1980 • 206 citations

Intermittent sequential pneumatic compression of the legs in the prevention of venous stasis and postoperative deep venous thrombosis.

1980 • 187 citations

Transcutaneous oxygen tension and capillary morphologic characteristics and density in patients with chronic venous incompetence.

1984 • 179 citations

Venous Insufficiency Of The Lower Limb And Stasis Ulceration

1983 • 177 citations

Compression Therapy of the Legs

1991 • 176 citations

A Phase II Study to Evaluate Recombinant Platelet-Derived Growth Factor-BB in the Treatment of Stage 3 and 4 Pressure Ulcers

1994 • 175 citations

Healing of venous ulcers in an ambulatory care program: The roles of chronic venous insufficiency and patient compliance

1995 • 175 citations

The relative importance of incompetent communicating veins in the production of varicose veins and venous ulcers.

1977 • 168 citations

Arterial disease in chronic leg ulceration: an underestimated hazard? Lothian and Forth Valley leg ulcer study.

1987 • 166 citations

Duplex scanning in the assessment of deep venous incompetence

1986 • 159 citations

Diagnosis of deep venous thrombosis. A prospective study comparing duplex scanning to contrast venography.

1989 • 157 citations

Quantification of venous reflux by means of duplex scanning.

1989 • 154 citations

Prospective 12-Year Follow-up Study of Clinical and Hemodynamic Sequelae After Deep Vein Thrombosis in Low-Risk Patients (Zürich Study)

1996 • 153 citations

Wound healing. The effects of topical antimicrobial agents

1979 • 153 citations

Long saphenous incompetence as a cause of venous ulceration

1984 • 151 citations

A comparison between descending phlebography and duplex Doppler investigation in the evaluation of reflux in chronic venous insufficiency: A challenge to phlebography as the “gold standard”

1992 • 150 citations

EFFECTS OF EXTERNAL PNEUMATIC INTERMITTENT COMPRESSION ON FIBRINOLYSIS IN MAN

1973 • 150 citations

Blood and vein-wall fibrinolytic activity in health and vascular disease.

1977 • 149 citations

Local Reflex in Microcirculation in Human Skeletal Muscle

1977 • 149 citations

Venous hemodynamic abnormalities in patients with leg ulceration

1995 • 139 citations

The influence of elastic compression stockings on deep venous hemodynamics

1991 • 136 citations

Management of Leg Ulcers With Hydrocolloid Occlusive Dressing

1984 • 132 citations

A physiological study of elastic compression stockings in venous disorders of the leg

1980 • 131 citations

Pneumatic calf compression, fibrinolysis, and the prevention of deep venous thrombosis.

1980 • 127 citations

Comparison of venous reflux assessed by duplex scanning and descending phlebography in chronic venous disease

1993 • 126 citations

Sequential gradient pneumatic compression enhances venous ulcer healing: a randomized trial.

1990 • 121 citations

Calf pump function in patients with healed venous ulcers is not improved by surgery to the communicating veins or by elastic stockings

1988 • 118 citations

Effect of Elastic Compression on Venous Hemodynamics in Postphlebitic Limbs

1979 • 115 citations

Correlation of clinical findings with venous hemodynamics in 386 patients with chronic venous insufficiency

1988 • 112 citations

Validation of air plethysmography, photoplethysmography, and duplex ultrasonography in the evaluation of severe venous stasis

1994 • 110 citations

A prospective, randomized trial of Unna's boot versus Duoderm CGF hydroactive dressing plus compression in the management of venous leg ulcers

1992 • 107 citations

Comparison of the effects of commonly used wound agents on epithelialization and neovascularization.

1994 • 105 citations

A prospective, randomized trial of Unna's boots versus hydroactive dressing in the treatment of venous stasis ulcers.

1988 • 102 citations

Real-time B-mode ultrasonography for better specificity in the noninvasive diagnosis of deep venous thrombosis.

1986 • 96 citations

Consensus Paper on Venous Leg Ulcer

1992 • 91 citations

Systemic administration of antibiotics in the management of venous ulcers

1986 • 90 citations

[Improving the venous pumping function in chronic venous insufficiency by compression as dependent on pressure and material].

1984 • 89 citations

The effect of elastic stockings on superficial venous pressures in patients with venous insufficiency

1974 • 88 citations

The development of valvular incompetence after deep vein thrombosis: A 7 year follow-up study with Duplex scanning

1996 • 87 citations

Real-time ultrasound diagnosis of deep vein thrombosis: A comparison with venography

1987 • 86 citations

Abnormal lymph drainage in patients with chronic venous leg ulcers

1993 • 82 citations

Effect of leg elevation on the skin microcirculation in chronic venous insufficiency

1994 • 80 citations

Do Dressings Influence the Healing of Chronic Venous Ulcers?

1988 • 76 citations

A prospective randomized evaluator-blinded trial of two potential wound healing agents for the treatment of venous stasis ulcers

1992 • 75 citations

Blood Flow in the Perimalleolar Skin in Relation to Posture in Patients with Venous Hypertension

1989 • 71 citations

Comparison of duplex ultrasonography and venography in the diagnosis of deep venous thrombosis

1991 • 67 citations

The role of external compression and movement in lymph propulsion in the sheep hind limb.

1987 • 66 citations

Effect of Venous Occlusion on Coagulation and Fibrinolytic Components in Normal Subjects

1968 • 65 citations

Comparison of two occlusive bandages in the treatment of venous leg ulcers

1986 • 60 citations

The fibrinolytic activity of varicose veins

1979 • 60 citations

White cell accumulation in dependent legs of patients with venous hypertension: a possible mechanism for trophic changes in the skin

1989 • 59 citations

Deep vein thrombosis: a 7‐year follow‐up study

1993 • 58 citations

Venous thromboembolism. Scope of the problem

1986 • 54 citations

Anatomy of the Superficial Venous System

1995 • 52 citations

Noninvasive diagnostic assessment of peripheral vascular disease.

1991 • 48 citations

Prospective Randomized Study Comparing the Debriding Effect of Krill Enzymes and a Non-Enzymatic Treatment in Venous Leg Ulcers

1990 • 43 citations

Compression treatment in venous insufficiency evaluated with foot volumetry.

1977 • 42 citations

Perimalleolar subcutaneous tissue pressure effects of elastic compression stockings

1993 • 40 citations

The mode of action of aescin on isolated veins: Relationship with PGF2α

1978 • 39 citations

The etiology of venous ulceration

1986 • 37 citations

Low anti-streptokinase IgG concentrations following streptokinase-streptodornase treatment of leg ulcer patients.

1994 • 37 citations

Transcutaneous oxygen tension in chronic venous insufficiency syndrome.

1984 • 35 citations

Chronic venous insufficiency of the lower extremity.

1961 • 33 citations

Cutaneous Microcirculation in Skin Lesions Associated with Chronic Venous Insufficiency

1995 • 32 citations

Fluorescence microlymphography in chronic venous incompetence.

1989 • 32 citations

Influence of phlebographic abnormalities on the natural history of venous ulceration

1991 • 24 citations

Recurrence and Late Sequelae after First-Time Deep Vein Thrombosis: Relationship to Initial Signs

1993 • 22 citations

Mupirocin treatment of exudative venous ulcers

1993 • 21 citations

Microcirculatory Aspects of Venous Ulceration

1994 • 21 citations

Patients evaluated for venous disease may have other pathologic conditions contributing to symptomatology

1993 • 15 citations

Effect of venous hypertension on canine hind limb lymph

1985 • 15 citations

Increasing erythrocyte aggregability with the progressive grades of chronic venous insufficiency: importance and mechanisms.

1995 • 13 citations

Changes in endothelial cell mass, luminal volume and capillary number in the gravitational syndrome

1989 • 13 citations

Importance of red cell aggregation in venous pathology

2016 • 12 citations

Pressure decrease in the dorsal pedal veins on walking in persons with and without thrombosis. A study of a fracture series.

1968 • 8 citations

Medical Management of the Peripheral Vascular Ulcer

1979 • 1 citations