BRCA1 RING Domain Cancer-predisposing Mutations

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

RING Finger Proteins

2000 • 1,216 citations

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1999 • 1,134 citations

Studying noncovalent protein complexes by electrospray ionization mass spectrometry

1997 • 1,128 citations

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

1997 • 910 citations

Structure of a c-Cbl–UbcH7 Complex

2000 • 824 citations

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1996 • 734 citations

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

1998 • 688 citations

The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation

2001 • 623 citations

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.

2001 • 471 citations

The RING finger domain: a recent example of a sequence—structure family

1996 • 464 citations

Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

2001 • 357 citations

The BARD1-CstF-50 Interaction Links mRNA 3′ End Formation to DNA Damage and Tumor Suppression

2001 • 210 citations

Probing the solution structure of the DNA‐binding protein Max by a combination of proteolysis and mass spectrometry

1995 • 161 citations

Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

1997 • 143 citations

Mapping the Functional Domains of BRCA1

1999 • 138 citations

The Cancer-predisposing Mutation C61G Disrupts Homodimer Formation in the NH2-terminal BRCA1 RING Finger Domain

1998 • 84 citations

Sequential Metal Binding by the RING Finger Domain of BRCA1

1997 • 53 citations