The biology and biochemistry of the glucose transporter

Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane.

1980 • 1,066 citations

Potential mechanism of insulin action on glucose transport in the isolated rat diaphragm. Apparent translocation of intracellular transport units to the plasma membrane.

1981 • 852 citations

Elevated Levels of Glucose Transport and Transporter Messenger RNA Are Induced by ras or src Oncogenes

1987 • 789 citations

Regulation in metabolism

1973 • 780 citations

Brain metabolism: a perspective from the blood-brain barrier

1983 • 745 citations

Regulation in Metabolism

1974 • 607 citations

Viral oncogenes

1985 • 605 citations

Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity.

1981 • 456 citations

Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: Characterization of subcellular fractions

1983 • 432 citations

PREPARATION AND CHARACTERIZATION OF A PLASMA MEMBRANE FRACTION FROM ISOLATED FAT CELLS

1970 • 402 citations

HORMONAL REGULATION OF MAMMALIAN GLUCOSE TRANSPORT

1986 • 399 citations

Myosin light chain phosphorylation in fast and slow skeletal muscles in situ

1984 • 330 citations

Mechanism of insulin action on glucose transport in the isolated rat adipose cell. Enhancement of the number of functional transport systems.

1978 • 330 citations

The gradient hypothesis and other models of carrier-mediated active transport

2005 • 327 citations

Sugar transport in the red blood cell: structure-activity relationships in substrates and antagonists.

1961 • 301 citations

Transformation of Rat Fibroblasts by FSV Rapidly Increases Glucose Transporter Gene Transcription

1987 • 286 citations

Glucose Uptake by Incubated Rat Epididymal Adipose Tissue

1965 • 260 citations

Biochemical Studies on the Mode of Action of Cytochalasin B

1974 • 256 citations

Membrane Transport: Its Relation to Cellular Metabolic Rates

1975 • 255 citations

BACTERIAL PERMEASES1

1957 • 236 citations

Mechanisms of the ability of insulin to activate the glucose-transport system in rat adipocytes

1978 • 229 citations

Energy-dependent and protein synthesis-independent recycling of the insulin-sensitive glucose transport mechanism in fat cells.

1981 • 210 citations

Biochemistry of the Na+, d-glucose cotransporter of the small-intestinal brush-border membrane

1984 • 202 citations

Distribution of glucose transporter messenger RNA transcripts in tissues of rat and man.

1987 • 190 citations

Further studies of proximal tubular brush border membraned-glucose transport heterogeneity

1982 • 183 citations

Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.

1987 • 180 citations

The human glucose transporter can insert posttranslationally into microsomes

1986 • 176 citations

The fat cell adenylate cyclase system. Characterization and manipulation of its bimodal regulation by GTP.

1979 • 171 citations

The regulation of glucose transport by cAMP stimulators via three different mechanisms in rat and human adipocytes.

1983 • 170 citations

cAMP-dependent protein kinase and lipolysis in rat adipocytes. III. Multiple modes of insulin regulation of lipolysis and regulation of insulin responses by adenylate cyclase regulators.

1985 • 165 citations

Activation of glucose transport in muscle by prolonged exposure to insulin. Effects of glucose and insulin concentrations.

1986 • 160 citations

Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and antilipolytic agents.

1987 • 158 citations

beta-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes.

1983 • 156 citations

Glucose deprivation and hexose transporter polypeptides of murine fibroblasts.

1986 • 149 citations

Photoaffinity labeling of the human erythrocyte D-glucose transporter.

1982 • 147 citations

Counter-regulation of insulin-stimulated glucose transport by catecholamines in the isolated rat adipose cell.

1984 • 140 citations

Insulin-stimulated glucose transport in rat adipose cells. Modulation of transporter intrinsic activity by isoproterenol and adenosine.

1986 • 132 citations

The glucose transporter in 3T3-L1 adipocytes is phosphorylated in response to phorbol ester but not in response to insulin.

1986 • 121 citations

Photoaffinity labeling of insulin-sensitive hexose transporters in intact rat adipocytes. Direct evidence that latent transporters become exposed to the extracellular space in response to insulin.

1984 • 120 citations

Stereospecific transport of glucose in the perfused rat liver

1968 • 118 citations

Sugar transport by the bacterial phosphotransferase system. Molecular cloning and structural analysis of the Escherichia coli ptsH, ptsI, and crr genes.

1987 • 116 citations

Characterization of the glucose transporter from human erythrocytes

1978 • 115 citations

The monosaccharide transporter from human erythrocytes is heterogeneously glycosylated

1979 • 110 citations

On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones.

1975 • 106 citations

The Action of Insulin on Cells

2014 • 104 citations

The monosaccharide transport system of the human erythrocyte. Solubilization and characterization on the basis of cytochalasin B binding.

1978 • 103 citations

Insulin action on glucose transport in cardiac muscle.

1984 • 103 citations

Detection of the rat adipose cell glucose transporter with antibody against the human red cell glucose transporter

1982 • 103 citations

Kinetics of 3-O-methyl-D-glucose transport in isolated rat hepatocytes

1979 • 101 citations

Blood-Brain Glucose Transfer In Diabetes Mellitus: Decreased Number of Glucose Transporters at Blood-Brain Barrier

1986 • 97 citations

Monoclonal antibodies to the glucose transporter from human erythrocytes. Identification of the transporter as a Mr = 55,000 protein.

1985 • 94 citations

Increased affinity predominates in insulin stimulation of glucose transport in the adipocyte.

1985 • 93 citations

Immunological identification of an insulin-responsive glucose transporter

1982 • 92 citations

Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes.

1985 • 90 citations

Transport of Hexoses across the Liver‐Cell Membrane

1977 • 90 citations

Substrate regulation of the glucose transport system in rat skeletal muscle. Characterization and kinetic analysis in isolated soleus muscle and skeletal muscle cells in culture.

1986 • 89 citations

Stimulation of glucose transport in rat adipocytes by insulin, adenosine, nicotinic acid and hydrogen peroxide. Role of adenosine 3′:5′-cyclic monophosphate

1979 • 89 citations

Activity and phosphorylation state of glucose transporters in plasma membranes from insulin-, isoproterenol-, and phorbol ester-treated rat adipose cells.

1987 • 87 citations

Unique cytochalasin B binding characteristics of the hepatic glucose carrier

1983 • 80 citations

Photolabeling of glucose-sensitive cytochalasin B binding proteins in erythrocyte, fibroblast and adipocyte membranes

1982 • 73 citations

Uptake of materials by the intact liver. The exchange of glucose across the cell membranes.

1974 • 72 citations

Dissociation of insulin-stimulated glucose transport from the translocation of glucose carriers in rat adipose cells.

1987 • 72 citations

Distribution of the Glucose Transporter in the Mammalian Brain

1986 • 69 citations

Biochemical and functional characterization of the rat liver glucose-transport system Comparisons with the adipocyte glucose-transport system

1986 • 66 citations

Purification and reconstitution of the adipocyte plasma membrane D-glucose transport system

1977 • 65 citations

Glucose transport in Leishmania donovani promastigotes

1984 • 65 citations

Glucose-specific cytochalasin B binding is increased in chicken embryo fibroblasts transformed by Rous sarcoma virus.

1979 • 64 citations

Rapid kinetics of the glucose transporter from human erythrocytes. Detection and measurement of a half-turnover of the purified transporter.

1985 • 57 citations

Biochemical and functional heterogeneity of rat adipocyte glucose transporters.

1986 • 56 citations

Identification of the glucose transporter in rat skeletal muscle

1983 • 54 citations

Role of intracellular energy in insulin's ability to activate 3-O-methylglucose transport by rat adipocytes

1980 • 50 citations

Isolation of vesicles containing insulin-responsive, intracellular glucose transporters from 3T3-L1 adipocytes.

1986 • 48 citations

Orientation of the glucose transporter in the human erythrocyte membrane. Investigation by in situ proteolytic dissection.

1984 • 45 citations

Human Erythrocyte Sugar Transport

1974 • 44 citations

Identification of the glucose transport protein of the microvillous membrane of human placenta by photoaffinity labelling

1982 • 38 citations

A rapid method of reconstituting human erythrocyte sugar transport proteins

1984 • 37 citations

Insulin-Stimulated Glucose Uptake by Subcellular Particles from Adipose Tissue Cells

1970 • 37 citations

Identification and biochemical characterization of the plasma membrane glucose transporter of Leishmania donovani.

1986 • 31 citations

Blood-brain glucose transfer in diabetes mellitus. Decreased number of glucose transporters at blood-brain barrier

1986 • 26 citations

Sugar transport across the hepatocyte plasma membrane

1982 • 25 citations

Identification and characterization of the rat adipocyte glucose transporter by photoaffinity crosslinking

1983 • 24 citations

Kinetic relationships between insulin receptor binding and effects on glucose transport in isolated rat adipocytes

1982 • 23 citations

Human adipocyte glucose transport system. Biochemical and functional heterogeneity of hexose carriers.

1987 • 23 citations

Modulation of basal glucose transporter Km in the adipocyte by insulin and other factors.

1986 • 22 citations

Insulin stimulation of glucose transport in isolated rat adipocytes. Functional evidence for insulin activation of intrinsic transporter activity within the plasma membrane

1985 • 22 citations

Biochemical characterization and subcellular distribution of the glucose transporter from rat brain microvessels

1987 • 19 citations

Inactivation of the renal outer cortical brush-border membrane D-glucose transporter by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline.

1986 • 17 citations

An improved and simplified apparatus for protein extraction and concentration from gel slices, using moving boundary electrophoresis

1983 • 13 citations

Characterization and solubilization of the cytochalasin B binding component from human placental microsomes

1984 • 12 citations

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