In vitro and in vivo effects of leukotriene B4 antagonism in a primate model of asthma.

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

The biology of interleukin-6

1989 • 1,964 citations

Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution

1986 • 1,093 citations

Cytokines in symptomatic asthma airways

1992 • 750 citations

Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation.

1993 • 561 citations

Late Asthmatic Responses

1987 • 538 citations

Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis.

1995 • 313 citations

Leukotriene B4 in inflammation.

1990 • 294 citations

Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils.

1993 • 287 citations

Leukotriene B4 induces airway hyperresponsiveness in dogs

1985 • 179 citations

Granulocyte chemotactic protein/interleukin-8 induces plasma leakage and neutrophil accumulation in rabbit skin.

1989 • 149 citations

Effects of intravenous IL-8 administration in nonhuman primates.

1992 • 138 citations

Upregulation of formyl-peptide and interleukin-8—induced eosinophil chemotaxis in patients with allergic asthma

1993 • 125 citations

Leukotriene B₄ transcriptionally activates interleukin‐6 expression involving NK‐xB and NF‐IL6

1992 • 109 citations

Repeated antigen inhalation results in a prolonged airway eosinophilia and airway hyperresponsiveness in primates

1990 • 108 citations

Effects of rolipram on responses to acute and chronic antigen exposure in monkeys.

1994 • 101 citations

Chemotactic potency of recombinant human neutrophil attractant/activation protein-1 (interleukin-8) for polymorphonuclear leukocytes of different species

1991 • 92 citations

The Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 84 citations

Tracheobronchial mucociliary clearance in asthma: impairment during remission.

1985 • 77 citations

The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696.

1995 • 63 citations

Leukotriene B4 stimulates human polymorphonuclear leukocytes to synthesize and release interleukin-8 in vitro.

1994 • 61 citations

Effects of Leukotriene B₄Inhalation: Airway Sensitization and Lung Granulocyte Infiltration in the Guinea Pig

1987 • 53 citations

Inhibition of human neutrophil chemotaxis by the protein kinase inhibitor, 1-(5-isoquinolinesulfonyl) piperazine.

1987 • 41 citations

The role of 5-lipoxygenase products in preclinical models of asthma

1993 • 33 citations

Dynamic respiratory mechanics in monkeys measured by forced oscillations

1984 • 28 citations

Inhibition of human mononuclear cell proliferation, interleukin synthesis, mRNA for IL-2, IL-6, and leukotriene B4 synthesis by a lipoxygenase inhibitor

1993 • 20 citations

Airway Hyperresponsiveness, Airway Inflammation, and Asthma

1990 • 15 citations