Level detection in ion channel records via idealization by statistical filtering and likelihood optimization

Maximum Likelihood from Incomplete Data Via the EM Algorithm

1977 • 46,601 citations

A tutorial on hidden Markov models and selected applications in speech recognition

1989 • 22,242 citations

Time Series Analysis: Forecasting and Control

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Handbook of Mathematical Functions with Formulas, Graphs, and Mathematical Tables

1965 • 17,314 citations

Handbook of Mathematical Functions with Formulas, Graphs and Mathematical Tables.

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Fitting and Statistical Analysis of Single-Channel Records

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Discrete Random Signals and Statistical Signal Processing

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The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

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Handbook of Mathematical Functions, with Formulas, Graphs, and Mathematical Tables

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Estimating kinetic constants from single channel data

1983 • 307 citations

Forward-backward non-linear filtering technique for extracting small biological signals from noise

1991 • 201 citations

Statistical methods for model discrimination. Applications to gating kinetics and permeation of the acetylcholine receptor channel

1987 • 199 citations

Characterization of single channel currents using digital signal processing techniques based on Hidden Markov Models

1990 • 183 citations

The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

1983 • 167 citations

Ion channel subconductance states

1987 • 136 citations

Maximum likelihood estimation and identification directly from single-channel recordings

1992 • 134 citations

Sodium channel subconductance levels measured with a new variance-mean analysis.

1988 • 122 citations

Statistical discrimination of fractal and Markov models of single-channel gating

1988 • 95 citations

Bayesian Restoration of Single-Channel Patch Clamp Recordings

1992 • 82 citations

Estimating kinetic parameters for single channels with simulation. A general method that resolves the missed event problem and accounts for noise

1990 • 72 citations

A new algorithm for idealizing single ion channel data containing multiple unknown conductance levels

1996 • 72 citations

Identifying kinetic gating mechanisms for ion channels by using two-dimensional distributions of simulated dwell times

1990 • 58 citations

Open channel noise. VI. Analysis of amplitude histograms to determine rapid kinetic parameters

1991 • 55 citations

A nonlinear filter algorithm for the detection of jumps in patch-clamp data

1993 • 55 citations

Guide to Data Acquisition and Analysis

1995 • 52 citations

Multiple conductances in the large K+ channel from Chara corallina shown by a transient analysis method

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Analysing ion channels with hidden Markov models

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An Example of Analysis

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Automated Analysis of Single-Channel Records

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[53] Preventing artifacts and reducing errors in single-channel analysis

1992 • 28 citations

[51] Stationary single-channel analysis

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Use of conditional distributions in the analysis of ion channel recordings

1991 • 16 citations

A robust running-window detector and estimator for step-signals in contaminated Gaussian noise

1986 • 16 citations

Automatic segmentation and classification of ionic-channel signals

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[50] Software for acquisition and analysis of ion channel data: Choices, tasks, and strategies

1992 • 12 citations

Step-like signal processing with distinct finite number of levels

1988 • 12 citations

Constraint optimum well-log signal segmentation

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Wahrscheinlichkeitsrechnung und Statistik

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Predictive optimality criterion for idealization of ion channel data and exact Akaike's criterion

1997 • 1 citations

Deleted Work

1955 • 0 citations