Hydrogen peroxide‐ and glutathione‐associated mechanisms of acclimatory stress tolerance and signalling

H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response

1994 • 2,757 citations

The presence of glutathione and glutathione reductase in chloroplasts: A proposed role in ascorbic acid metabolism

1976 • 2,480 citations

Superoxide Dismutase and Stress Tolerance

1992 • 2,444 citations

The role of active oxygen in the response of plants to water deficit and desiccation

1993 • 1,990 citations

CARBOHYDRATE-MODULATED GENE EXPRESSION IN PLANTS

1996 • 1,760 citations

Photooxidative stress in plants

1994 • 1,742 citations

Resistance gene-dependent plant defense responses.

1996 • 1,660 citations

Ascorbate peroxidase – a hydrogen peroxide‐scavenging enzyme in plants

1992 • 1,433 citations

THE FUNCTIONS AND REGULATION OF GLUTATHIONE S-TRANSFERASES IN PLANTS

1996 • 1,349 citations

The Roles Of Heat Shock Proteins In Plants

1991 • 1,314 citations

Protection against oxygen radicals: an important defence mechanism studied in transgenic plants

1994 • 1,249 citations

Elicitor- and wound-induced oxidative cross-linking of a proline-rich plant cell wall protein: A novel, rapid defense response

1992 • 1,191 citations

Active Oxygen Species in the Induction of Plant Systemic Acquired Resistance by Salicylic Acid

1993 • 1,186 citations

Evidence for Chilling-Induced Oxidative Stress in Maize Seedlings and a Regulatory Role for Hydrogen Peroxide.

1994 • 998 citations

Causes of Photooxidative Stress and Amelioration of Defense Systems in Plants

2019 • 955 citations

Gene expression in response to abscisic acid and osmotic stress.

1990 • 933 citations

Cold calcium signaling in Arabidopsis involves two cellular pools and a change in calcium signature after acclimation.

1996 • 842 citations

ROLE OF REVERSIBLE OXIDATION-REDUCTION OF ENZYME THIOLS-DISULFIDES IN METABOLIC REGULATION

1985 • 840 citations

Active Oxygen Species in Plant Defense against Pathogens

1994 • 836 citations

Active Oxygen in Plant Pathogenesis

1995 • 829 citations

Vegetation Stress: an Introduction to the Stress Concept in Plants

1996 • 777 citations

Dissection of Oxidative Stress Tolerance Using Transgenic Plants

1995 • 761 citations

Oxygen Activation and Oxygen Toxicity

1982 • 713 citations

Rapid Stimulation of an Oxidative Burst during Elicitation of Cultured Plant Cells

1989 • 670 citations

Light intensity regulation of cab gene transcription is signaled by the redox state of the plastoquinone pool.

1995 • 649 citations

Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli.

1990 • 555 citations

Biosynthesis and antioxidant function of glutathione in plants

1989 • 484 citations

Chilling-Enhanced Photooxidation

1987 • 468 citations

Overexpression of Glutathione Reductase but Not Glutathione Synthetase Leads to Increases in Antioxidant Capacity and Resistance to Photoinhibition in Poplar Trees

1995 • 461 citations

Toxic oxygen species and protective systems of the chloroplast

1988 • 450 citations

The oxidative burst in plant defense: Function and signal transduction

1996 • 442 citations

Catalases in plants

1995 • 437 citations

Ultraviolet light and ozone stimulate accumulation of salicylic acid, pathogenesis-related proteins and virus resistance in tobacco

1994 • 430 citations

Abrupt Increase in the Level of Hydrogen Peroxide in Leaves of Winter Wheat Is Caused by Cold Treatment

1991 • 428 citations

Hydrogen Peroxide Stimulates Salicylic Acid Biosynthesis in Tobacco

1995 • 424 citations

Oxidative Stimulation of Glutathione Synthesis in Arabidopsis thaliana Suspension Cultures

1993 • 419 citations

Differential regulation of superoxide dismutases in plants exposed to environmental stress.

1991 • 419 citations

Function of the oxidative burst in hypersensitive disease resistance.

1995 • 417 citations

UV-B damage and protection at the molecular level in plants

1994 • 415 citations

Inhibition of ascorbate peroxidase by salicylic acid and 2,6-dichloroisonicotinic acid, two inducers of plant defense responses.

1995 • 402 citations

Oxidative damage and defense mechanisms in primary leaves of Phaseolus vulgaris as a result of root assimilation of toxic amounts of copper

1996 • 398 citations

Disease resistance conferred by expression of a gene encoding H2O2-generating glucose oxidase in transgenic potato plants.

1995 • 391 citations

The Origin of the Oxidative Burst in Plants

1995 • 381 citations

Oxidative Signals in Tobacco Increase Cytosolic Calcium.

1994 • 371 citations

Ozone-induced responses in Arabidopsis thaliana: the role of salicylic acid in the accumulation of defense-related transcripts and induced resistance.

1996 • 367 citations

Glutathione Causes a Massive and Selective Induction of Plant Defense Genes

1988 • 362 citations

A Cadmium-Sensitive, Glutathione-Deficient Mutant of Arabidopsis thaliana

1995 • 354 citations

The generation of oxygen radicals during host plant responses to infection

1991 • 346 citations

Evidence for Chilling-Induced Oxidative Stress in Maize Seedlings and a Regulatory Role for Hydrogen Peroxide

1994 • 346 citations

Phenylpropanoid metabolism and lignin biosynthesis: from weeds to trees

1996 • 337 citations

Systemic Acquired Resistance Mediated by the Ectopic Expression of Invertase: Possible Hexose Sensing in the Secretory Pathway.

1996 • 335 citations

Feedback control of gene expression

1994 • 334 citations

Light-Regulated Translation of Chloroplast Messenger RNAs Through Redox Potential

1994 • 330 citations

Does the alternative pathway ameliorate chilling injury in sensitive plant tissues?

1993 • 316 citations

Old Enzymes for a New Job (Herbicide Detoxification in Plants)

1996 • 301 citations

Amelioration of Ozone-Induced Oxidative Damage in Wheat Plants Grown under High Carbon Dioxide (Role of Antioxidant Enzymes)

1995 • 293 citations

Plant metabolism under hypoxia and anoxia

1994 • 283 citations

Lignin Biosynthesis

1995 • 274 citations

Stimulation of Glutathione Synthesis in Photorespiring Plants by Catalase Inhibitors

1985 • 272 citations

Chilling, oxidative stress and antioxidant responses inArabidopsis thaliana callus

1996 • 270 citations

Sugar-Dependent Expression of the CHS-A Gene for Chalcone Synthase from Petunia in Transgenic Arabidopsis

1991 • 262 citations

Differential Induction of Distinct Glutathione-S-Transferases of Wheat by Xenobiotics and by Pathogen Attack

1993 • 262 citations

Hydrogen peroxide does not function downstream of salicylic acid in the induction of PR protein expression

1995 • 260 citations

Effects of Elevated Cytosolic Glutathione Reductase Activity on the Cellular Glutathione Pool and Photosynthesis in Leaves under Normal and Stress Conditions

1991 • 256 citations

UV-B-Induced PR-1 Accumulation Is Mediated by Active Oxygen Species.

1995 • 253 citations

Molecular cloning and characterization of a gene encoding pea cytosolic ascorbate peroxidase.

1992 • 252 citations

Elevated Levels of Superoxide Dismutase Protect Transgenic Plants Against Ozone Damage

1994 • 245 citations

Logjam at the Styx: programmed cell death in plants

1996 • 243 citations

The induction of manganese superoxide dismutase in response to stress in Nicotiana plumbaginifolia.

1989 • 233 citations

The plant 2‐Cys peroxiredoxin BAS1 is a nuclear‐encoded chloroplast protein: its expressional regulation, phylogenetic origin, and implications for its specific physiological function in plants

1997 • 232 citations

Is hydrogen peroxide a second messenger of salicylic acid in systemic acquired resistance?

1995 • 229 citations

Enhanced Superoxide Radical Production in Roots of Zinc-Deficient Plants

1988 • 218 citations

Oligopeptide elicitor-mediated defense gene activation in cultured parsley cells.

1995 • 216 citations

A sulfhydryl-disulfide hypothesis of frost injury and resistance in plants

1962 • 213 citations

Peroxide Levels and the Activities of Catalase, Peroxidase, and Indoleacetic Acid Oxidase during and after Chilling Cucumber Seedlings

1980 • 212 citations

Phospholipase C activation during elicitation of the oxidative burst in cultured plant cells.

1993 • 212 citations

Turning on the respiratory burst

1990 • 211 citations

Involvement of Reactive Oxygen Species, Glutathione Metabolism, and Lipid Peroxidation in the Cf-Gene-Dependent Defense Response of Tomato Cotyledons Induced by Race-Specific Elicitors of Cladosporium fulvum

1996 • 211 citations

Synthesis of Glutathione in Leaves of Transgenic Poplar Overexpressing [gamma]-Glutamylcysteine Synthetase

1996 • 204 citations

The role of activated oxygen species in plant disease resistance

1996 • 203 citations

A role for active oxygen species as second messengers in the induction of alternative oxidase gene expression in Petunia hybrida cells

1995 • 194 citations

Regulation of glutathione synthesis in leaves of transgenic poplar (Populus tremula X P. alba) overexpressing glutathione synthetase

1995 • 193 citations

Sunflower seedlings subjected to increasing water deficit stress: oxidative stress and defence mechanisms

1995 • 191 citations

Glutathione and fungal elicitor regulation of a plant defense gene promoter in electroporated protoplasts

1988 • 189 citations

Hydrogen peroxide-mediated cell-wall stiffening in vitro in maize coleoptiles

1996 • 187 citations

Sacrifice in the face of foes: Pathogen-induced programmed cell death in plants

1996 • 183 citations

Gene Expression in Response to Abscisic Acid and Osmotic Stress

1990 • 183 citations

Ascorbate is the natural substrate for plant peroxidases

1996 • 182 citations

Induction of superoxide dismutase in Escherichia coli by heat shock.

1987 • 173 citations

Effect of Specific Elicitors of Cladosporium fulvum on Tomato Suspension Cells

1992 • 168 citations

Unequivocal evidence in support of the nonenzymatic redox coupling between glutathione/glutathione disulfide and ascorbic acid/dehydroascorbic acid

1992 • 160 citations

Thylakoid protein phosphorylation, state 1‐state 2 transitions, and photosystem stoichiometry adjustment: redox control at multiple levels of gene expression

1995 • 153 citations

Redox-activated expression of the cytosolic copper/zinc superoxide dismutase gene in Nicotiana.

1993 • 151 citations

Mechanism of indole-3-acetic acid oxidation by plant peroxidases: anaerobic stopped-flow spectrophotometric studies on horseradish and tobacco peroxidases

1996 • 147 citations

Degradation of glutathione S‐conjugates by a carboxypeptidase in the plant vacuole

1996 • 147 citations

Ethylene‐promoted ascorbate peroxidase activity protects plants against hydrogen peroxide, ozone and paraquat

1990 • 145 citations

Oxidative Signals in Tobacco Increase Cytosolic Calcium

1994 • 144 citations

Alteration in Expression of Defence Genes in <italic>Pisum sativum</italic> after Exposure to Supplementary Ultraviolet-B Radiation

1993 • 143 citations

Plant and human neutrophil oxidative burst complexes contain immunologically related proteins

1996 • 137 citations

The Active Oxygen Response of Cell Suspensions to Incompatible Bacteria Is Not Sufficient to Cause Hypersensitive Cell Death

1996 • 133 citations

Systemic Acquired Resistance Mediated by the Ectopic Expression of Invertase: Possible Hexose Sensing in the Secretory Pathway

1996 • 131 citations

A Comparison of the Relative Rates of Transport of Ascorbate and Glucose Across the Thylakoid, Chloroplast and Plasmalemma Membranes of Pea Leaf Mesophyll Cells

1996 • 130 citations

Oxidative stress responses in transgenic tobacco containing altered levels of glutathione reductase activity

1995 • 124 citations

Oxidative Stress and the Molecular Biology of Antioxidant Defences

1997 • 122 citations

Modification of thiol contents in poplars ( Populus tremula × P. alba ) overexpressing enzymes involved in glutathione synthesis

1997 • 121 citations

Transcriptional Activation of the Cu,Zn-Superoxide Dismutase Gene through the AP2 Site by Ginsenoside Rb2 Extracted from a Medicinal Plant, Panax ginseng

1996 • 121 citations

Stress Responses and Metabolic Regulation of Glyceraldehyde-3-Phosphate Dehydrogenase Genes in Arabidopsis

1993 • 119 citations

Anaerobic Stress Induces the Transcription and Translation of Sucrose Synthase in Rice

1991 • 119 citations

Increased Activity of [gamma]-Glutamylcysteine Synthetase in Tomato Cells Selected for Cadmium Tolerance

1994 • 117 citations

THE MECHANISM OF CHILL‐ AND DROUGHT‐HARDENING OF PHASEOLUS VULGARIS LEAVES

1976 • 114 citations

Plant Morphological and Biochemical Responses to Field Water Deficits

1985 • 112 citations

Transposon tagging of tobacco mosaic virus resistance gene N: its possible role in the TMV-N-mediated signal transduction pathway.

1995 • 112 citations

Effect of zinc nutritional status on activities of superoxide radical and hydrogen peroxide scavenging enzymes in bean leaves

1993 • 111 citations

Phosphate Modulates Transcription of Soybean VspB and Other Sugar-Inducible Genes.

1994 • 109 citations

Glutathione and elicitation of the phytoalexin response in legume cell cultures

1991 • 106 citations

Cellular response to oxidative stress at sulfhydryl group receptor sites on the erythrocyte membrane.

1988 • 104 citations

Localization and Characterization of Peroxidases in the Mitochondria of Chilling-Acclimated Maize Seedlings

1995 • 101 citations

Chilling, oxidative stress and antioxidant responses in shoot cultures of rice

1996 • 98 citations

Green life: Control of chloroplast gene transcription

1996 • 97 citations

Involvement of Oxidative Processes in the Signaling Mechanisms Leading to the Activation of Glyceollin Synthesis in Soybean (Glycine max)

1994 • 97 citations

UV-B-Induced PR-1 Accumulation Is Mediated by Active Oxygen Species

1995 • 96 citations

Thiol Dependence of Nitric Oxide Synthase

1995 • 96 citations

Ascorbic acid effect on the onset of cell proliferation in pea root

1994 • 96 citations

The role of glycine in determining the rate of glutathione synthesis in poplar. Possible implications for glutathione production during stress

1997 • 95 citations

Paraquat tolerance of transgenic Nicotiana tabacum with enhanced activities of glutathione reductase and superoxide dismutase.

1995 • 94 citations

Effect of zinc nutritional status on activities of superoxide radical and hydrogen peroxide scavenging enzymes in bean leaves

1993 • 88 citations

The Arabidopsis thaliana apurinic endonuclease Arp reduces human transcription factors Fos and Jun.

1994 • 88 citations

In Vivo Phosphorus-31 Nuclear Magnetic Resonance Reveals Lowered ATP During Heat Shock of Tetrahymena

1983 • 87 citations

Long-term chilling of young tomato plants under low light and subsequent recovery

1992 • 87 citations

Identification of a Metabolite Produced byTalaromyces flavusas Glucose Oxidase and its Role in the Biocontrol ofVerticillium dahliae

1988 • 87 citations

Antioxidative protection in a drought‐resistant maize strain during leaf senescence

1993 • 87 citations

Early Responses During Plant-Bacteria Interactions in Tobacco Cell Suspensions

1991 • 86 citations

Thiol dependent oxidation of enzymes: The last chance against oxidative stress

1994 • 86 citations

Involvement of small GTP-binding proteins in defense signal-transduction pathways of higher plants.

1995 • 86 citations

Characterization of Glutathione Uptake in Broad Bean Leaf Protoplasts

1996 • 84 citations

Nicotinamide, a missing link in the early stress response in eukaryotic cells: A hypothesis with special reference to oxidative stress in plants

1994 • 82 citations

Hydrogen peroxide formation in cultured rose cells in response to UV‐C radiation

1990 • 81 citations

Elicitor stimulation of the defense response in cultured plant cells monitored by fluorescent dyes

1986 • 76 citations

Role of ascorbic acid in the metabolism of S‐nitroso‐glutathione

1996 • 75 citations

Cytochrome and Alternative Pathway Respiration in Tobacco (Effects of Salicylic Acid)

1993 • 73 citations

Significance of Thiol‐Disulfide Exchange in Resting Stages of Plant Development

1996 • 70 citations

Defensive and secondary metabolism in plant tissue cultures, with special reference to nicotinamide, glutathione and oxidative stress

1995 • 67 citations

Enzymes of the Calvin Cycle

1990 • 67 citations

The Roles of Sugar Phosphates and Thiol-Reducing Systems in the Control of Reticulocyte Protein Synthesis

1983 • 64 citations

Intramolecular disulfide bridges: avenues to receptor activation?

1987 • 59 citations

An improved method for monitoring active oxygen in bacteria-treated suspension cells using luminol-dependent chemiluminescence

1991 • 59 citations

Factors affecting gene expression of patatin and proteinase-inhibitor-II gene families in detached potato leaves:

1992 • 56 citations

Anionic peroxidase catalysed ascorbic acid and IAA oxidation in the presence of hydrogen peroxide: A defence system against peroxidative stress in peanut plant

1992 • 55 citations

Carbohydrate control of gene expression in higher plants

1996 • 55 citations

Long-term chilling of young tomato plants under low light and subsequent recovery

1992 • 52 citations

A comparison of the effects of a fungal elicitor and ultraviolet radiation on ion transport and hydrogen peroxide synthesis by rose cells

1991 • 52 citations

Long-distance Transport of Reduced Sulphur in Spruce (Picea abiesL.)

1992 • 51 citations

Processes involved in glutathione metabolism

1995 • 50 citations

Effects of Cytokinins and Antioxidants on the Susceptibility of Membranes to Ozone Damage

1982 • 48 citations

Hydrogen peroxide activates immediate binding of a Drosophila factor to DNA heat‐shock regulatory element in vivo and in vitro

1990 • 48 citations

Free radical production by the red tide alga,Chattonella antiqua

1991 • 46 citations

Activation of the potential of potato leaf tissue to react hypersensitively to Phytophthora infestans by cytospore germination fluid and the enhancement of this potential by calcium ions

1987 • 44 citations

Hydrogen peroxide plays a bivalent role in the regeneration of protoplasts

1996 • 44 citations

Drought enhances chilling tolerance in a chilling‐sensitive maize (Zea mays) variety

1996 • 44 citations

Inhibition of Elicitor-Induced Phytoalexin Formation in Cotton and Soybean Cells by Citrate

1987 • 43 citations

Oxidative stress responses and shock proteins in the unicellular cyanobacterium Synechococcus R2 (PCC-7942)

1991 • 43 citations

Effect of Intracellular Glutathione Level on the Production of 6-Methoxymellein in Cultured Carrot (Daucus carota) Cells

1993 • 42 citations

Recognition responses in pathogen/non-host and race/cultivar interactions involving soybean (Glycine max) and Pseudomonas syringae pathovars

1993 • 40 citations

AnArabidopsisMutant Depleted in Glutathione Shows Unaltered Responses to Fungal and Bacterial Pathogens

1996 • 39 citations

Long-Lived and Short-Lived Heat-Shock Proteins in Tobacco Mesophyll Protoplasts

1983 • 39 citations

Role of Reversible Oxidation-Reduction of Enzyme Thiols-Dilsulfides in Metabolic Regulation

1985 • 38 citations

Phosphate Modulates Transcription of Soybean VspB and Other Sugar-Inducible Genes

1994 • 37 citations

Identification and localization of the first glutaredoxin in leaves of a higher plant

1995 • 36 citations

Relationship between apoplastic ascorbate regeneration and the stimulation of root growth in Allium cepa L.

1994 • 34 citations

Molecular biology of free radical scavenging systems

1995 • 32 citations

Induction of ascorbate peroxidase activity in stressed pine (Pinus sylvestris L.) needles: a putative role for ethylene

1995 • 31 citations

Null thioredoxin and glutaredoxin Escherichia coli K-12 mutants have no enhanced sensitivity to mutagens due to a new GSH-dependent hydrogen donor and high increases in ribonucleotide reductase activity

1994 • 28 citations

Calmodulin-binding proteins from Zea mays germs

1995 • 26 citations

Induction of stress proteins in SV-40 transformed human RPE-derived cells by organic oxidants

1992 • 25 citations

Regulation by sulfhydryl groups of glyceollin accumulation in soybean hypocotyls

1984 • 25 citations

Phenylpropanoid defence responses in transgenicLotus corniculatus

1995 • 25 citations

Variations in the activity of glutathione reductase and the cellular glutathione content in relation to sensitivity to methylviologen in Escherichia coli

1990 • 25 citations

Effect of Nicotinamide on Gene Expression and Glutathione Levels in Tissue Cultures of Pisum sativum

1993 • 24 citations

Enhanced Formation of a Constitutive Sesquiterpenoid in Cultured Cells of a Liverwort, <italic>Calypogeia granulata</italic> Inoue during Elicitation; Effects of Vanadate

1993 • 21 citations

Regulation of Protein Synthesis by Hydrogen Peroxide in Crowns of Winter Wheat

1994 • 21 citations

Induction of Medicarpin Biosynthesis in Ladino Clover Callus by p-Chloromercuribenzoic Acid Is Reversed by Dithiothreitol

1987 • 19 citations

Glutathione, a Regulator of Chloroplast Transcription

1997 • 19 citations

Photosynthesis gene expression in Rhodobacter sphaeroides is regulated by redox changes which are linked to electron transport

1996 • 14 citations

Response of hydrogen peroxide scavenging system in two soybean cultivars exposed to SO2: experimental evidence for the detoxification of SO2 by enhanced H2O2 scavenging components

1993 • 8 citations

Stress Responses in Cell Cultures of Lolium temulentum. I. Transcriptional and Post-transcriptional Changes in Gene Expression During Heat Shock and Recovery

1995 • 5 citations

Different stress factor signals converge at phosphoinositide turnover in Drosophila cells

1996 • 2 citations