Homochiral structures derived from 1-[1-(2-thienyl)cyclohexyl]piperidine (TCP) are potent non-competitive antagonists of glutamate at NMDA receptor sites

[3H]TCP: a new tool with high affinity for the PCP receptor in rat brain

1983 • 156 citations

[3H]Thienyl-phencyclidine ([3H]TCP) binds to two different sites in rat brain. Localization by autoradiographic and biochemical techniques

1986 • 116 citations

Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by PCP analogs

1989 • 81 citations

Non‐competitive antagonists of N‐methyl‐D‐aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex

1991 • 41 citations

Non-competitive antagonists of receptors protect cortical and hippocampal cell cultures against glutamate neurotoxicity

1988 • 33 citations

Conformational determination of phencyclidine derivatives for a structure activity correlation

1979 • 29 citations

Arylcyclohexylamines derived from BTCP are potent indirect catecholamine agonists

1993 • 19 citations

Synthesis, pharmacological action, and receptor binding affinity of the enantiomeric 1-(1-phenyl-3-methylcyclohexyl)piperidines

1988 • 17 citations

Comparaison entre les sites de fixation de la [3H]phencyclidine (PCP) et de la [3H](thiényl-2)-1 cyclohexylpipéridine (TCP) dans le système nerveux central de rat

1987 • 16 citations

TCP enhances the survival of human fetal spinal cord cells in culture

1992 • 16 citations

Synthesis, stereochemistry, and biological activity of the 1-(1-phenyl-2-methylcyclohexyl)piperidines and the 1-(1-phenyl-4-methylcyclohexyl)piperidines. Absolute configuration of the potent trans-(-)-1-(1-phenyl-2-methylcyclohexyl)piperidine

1991 • 14 citations

Neurotoxic effect of the anti-HIV drugd-aspartate β-hydroxamate for rat primary neuronal cultures: attenuation by N-methyl-d-aspartate (NMDA) antagonists

1993 • 12 citations