Identification of the Ras GTPase-activating protein GAP1m as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo

Signalling through the lipid products of phosphoinositide-3-OH kinase

1997 • 1,314 citations

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

1997 • 1,064 citations

Structure and function of phosphoinositide 3-kinases

1998 • 666 citations

Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation.

1996 • 568 citations

The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

1998 • 183 citations

Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells.

1992 • 142 citations

Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain

1998 • 126 citations

Ras-GTPase Activating Protein (GAP): A Putative Effector for Ras

1997 • 105 citations

p120 GAP Modulates Ras Activation of Jun Kinases and Transformation

1997 • 97 citations

Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting

1997 • 88 citations

Structure-Function Relationships of the Mouse Gap1m

1996 • 80 citations

Ras-GAP Controls Rho-Mediated Cytoskeletal Reorganization through Its SH3 Domain

1998 • 64 citations

Specific detection of phosphatidylinositol 3,4,5-trisphosphate binding proteins by the PIP3 analogue beads: An application for rapid purification of the PIP3 binding proteins

1998 • 44 citations

Bridging the GAP in inositol 1,3,4,5-tetrakisphosphate signalling

1998 • 44 citations

Activation of R-Ras GTPase by GTPase-activating Proteins for Ras, Gap1m, and p120GAP

1997 • 25 citations

An Effector-like Function of Ras GTPase-activating Protein Predominates in Cardiac Muscle Cells

1997 • 22 citations