Glutamine uptake and utilization by preimplantation mouse embryos in CZB medium

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

1979 • 1,228 citations

An improved culture medium supports development of random-bred 1-cell mouse embryos in vitro

1989 • 1,119 citations

The pattern of energy metabolism in the mouse oöcyte and zygote.

1967 • 686 citations

Development of Preimplantation Embryos of the Golden Hamster in a Defined Culture Medium

1983 • 671 citations

COMPLETE DEVELOPMENT IN VITRO OF THE PRE-IMPLANTATION STAGES OF THE MOUSE IN A SIMPLE CHEMICALLY DEFINED MEDIUM

1968 • 481 citations

THE GROWTH RESPONSE OF MAMMALIAN CELLS IN TISSUE CULTURE TO l-GLUTAMINE AND l-GLUTAMIC ACID

1956 • 349 citations

The beneficial effect of EDTA on development of mouse one-cell embryos in chemically defined medium

1977 • 291 citations

The effect of oxygen on the development of preimplantation mouse embryos in vitro

1978 • 238 citations

Glutamine: a major energy source for cultured mammalian cells.

1984 • 234 citations

Glucose, glutamine and inorganic phosphate in early development of the pig embryo in vitro

1990 • 191 citations

Amino acid uptake and protein synthesis in preimplantation mouse embryos

1973 • 136 citations

Hypoxanthine Causes a 2-Cell Block in Random-Bred Mouse Embryos1

1987 • 126 citations

Quantitative Determination of the Pentose Phosphate Pathway in Preimplantation Mouse Embryos1

1986 • 124 citations

Lactate: A major product of glutamine metabolism by human diploid fibroblasts

1980 • 119 citations

Measurement of the metabolism of energy substrates in individual bovine blastocysts

1988 • 109 citations

Amino acid transport in developing animal oocytes and early conceptuses

1988 • 109 citations

Growth of human diploid fibroblasts in the absence of glucose utilization.

1976 • 105 citations

Fallopian Tube and Early Cleavage in the Mouse

1967 • 105 citations

The sensitivity of one-cell mouse embryos to pyruvate and lactate

1973 • 102 citations

UPTAKE AND INCORPORATION OF AMINO ACIDS BY THE PREIMPLANTATION MOUSE EMBRYO

1971 • 94 citations

[44] Derivatives of glutamine in peptides

1967 • 92 citations

Requirements for the maturation of hamster oocytes in vitro

1973 • 92 citations

Effects of Actinomycin D and Cycloheximide on RNA and Protein Synthesis in Cleavage Stage Mouse Embryos

1970 • 91 citations

Activation of a Na+-dependent amino acid transport system in preimplantation mouse embryos

1974 • 86 citations

Stimulatory and inhibitory effects of amino acids on the development of hamster eight-cell embryos in vitro

1987 • 85 citations

Complete preimplantation development in culture of parthenogenetic mouse embryos

1976 • 72 citations

Influence of visible light and room temperature on cell proliferation in preimplantation rabbit embryos

1988 • 62 citations

Carbohydrate and amino acid requirements and ammonia production of rabbit follicular oocytes matured in vitro

1975 • 58 citations

End products of glucose and glutamine metabolism by L929 cells.

1987 • 52 citations

Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts

1981 • 52 citations

Development of a noninvasive ultramicrofluorometric method for measuring net uptake of glutamine by single preimplantation mouse embryos

1989 • 48 citations

THE METABOLISM OF SPECIFICALLY LABELLED LACTATE AND PYRUVATE BY TWO-CELL MOUSE EMBRYOS

1973 • 45 citations

Incorporation of carbon from glucose and pyruvate into the preimplantation mouse embryo

1969 • 42 citations

Metabolism of Specifically Labelled Pyruvate by Mouse Embryos During Culture from the Two-Cell Stage to the Blastocyst

1970 • 31 citations

A comparison of the uptake and utilization of lactate and pyruvate by one- and two-cell mouse embryos

1967 • 30 citations

Increase in Glutaminase Activity during the Growth Cycle of Cultured Human Diploid Fibroblasts

1980 • 21 citations

Modulation of amino acid transport in preimplantation mouse embryos by low concentrations of non-ionic and zwitterionic detergents

1984 • 13 citations