Cellular transformation and the ‘morphologic phenotype’ of transformed cells

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1977 • 931 citations

International cell biology 1976–1977

1978 • 762 citations

Cell surface proteins and malignant transformation

1976 • 713 citations

Role of Cyclic Nucleotides in Growth Control

1975 • 692 citations

Membrane receptors for hormones and neurotransmitters.

1976 • 573 citations

A DIFFERENCE IN THE ARCHITECTURE OF THE SURFACE MEMBRANE OF NORMAL AND VIRALLY TRANSFORMED CELLS

1969 • 549 citations

Morphological Transformation of Chinese Hamster Cells by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Testosterone

1971 • 529 citations

INTERACTION OF THE CARBOHYDRATE-BINDING PROTEIN CONCANAVALIN A WITH NORMAL AND TRANSFORMED CELLS

1969 • 525 citations

Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts.

1976 • 518 citations

Cyclic AMP levels in fibroblasts: Relationship to growth rate and contact inhibition of growth

1971 • 443 citations

Restoration of Several Morphological Characteristics of Normal Fibroblasts in Sarcoma Cells Treated with Adenosine-3′:5′-Cyclic Monophosphate and Its Derivatives

1971 • 440 citations

The effects of reciprocal changes in temperature on the transformed state of cells infected with a Rous sarcoma virus mutant

1971 • 411 citations

Glucose depletion accounts for the induction of two transformation-sensitive membrane proteinsin Rous sarcoma virus-transformed chick embryo fibroblasts.

1977 • 371 citations

Restoration of Contact-Inhibited Growth to Transformed Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1971 • 321 citations

Induction of lipogenesis during differentiation in a "preadipocyte" cell line.

1976 • 317 citations

Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells.

1975 • 317 citations

Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts.

1977 • 309 citations

Epithelioid and fibroblastic rat kidney cell clones: Epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation

1978 • 296 citations

Isolation of a Major Cell Surface Glycoprotein from Fibroblasts

1974 • 295 citations

Inhibition of Cell Growth in vitro by Adenosine 3′,5′-Monophosphate

1968 • 251 citations

Microfilament bundles and cell shape are related to adhesiveness to substratum and are dissociable from growth control in cultured fibroblasts

1977 • 231 citations

Further Changes in Differentiation State Accompanying the Conversion of Chinese Hamster Cells to Fibroblastic Form by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Hormones

1971 • 227 citations

Mechanism of the decrease in the major cell surface protein of chick embryo fibroblasts after transformation

1977 • 216 citations

Reduced Adenyl Cyclase Activity in a Polyoma Virus Transformed Cell Line

1968 • 214 citations

Temperature-dependent Mobility of Concanavalin a Sites on Tumour Cell Surfaces

1973 • 211 citations

Growth and maintenance of HeLa cells in serum-free medium supplemented with hormones.

1978 • 208 citations

Dimeric character of fibronectin, a major cell surface-associated glycoprotein

1977 • 196 citations

The molecular biology of tumour viruses

1973 • 183 citations

Cellular uptake and nuclear binding of insulin in human cultured lymphocytes: evidence for potential intracellular sites of insulin action.

1977 • 171 citations

BINDING OF HORMONE TO TISSUE: THE FIRST STEP IN POLYPEPTIDE HORMONE ACTION

1966 • 168 citations

Temperature-Dependent Alterations in Sugar Transport in Cells Infected by a Temperature-Sensitive Mutant of Rous Sarcoma Virus

1971 • 168 citations

Increasing activity of enzymes on pathway of triacylglycerol synthesis during adipose conversion of 3T3 cells.

1977 • 152 citations

Cyclic amp and cell morphology in cultured fibroblasts. Effects on cell shape, microfilament and microtubule distribution, and orientation to substratum.

1975 • 131 citations

N6,O2′-Dibutyryl Adenosine 3′,5′-Monophosphate induces Pigment Production in Melanoma Cells

1972 • 130 citations

A Mutation in a Rous Sarcoma Virus Gene That Controls Adenosine 3′,5′-Monophosphate Levels and Transformation

1972 • 130 citations

Studies on reactivity of tumor and normal cells to a wheat germ agglutinin.

1965 • 122 citations

Cyclic AMP and the Transformation of Fibroblasts

1974 • 115 citations

Temperature-Dependent Transformation of Cells Infected with a Mutant of Bryan Rous Sarcoma Virus

1972 • 112 citations

Cyclic AMP modulates microvillus formation and agglutinability in transformed and normal mouse fibroblasts.

1975 • 99 citations

Loss of Ability to Synthesize Collagen in Fibroblasts Transformed by Rous Sarcoma Virus 2

1975 • 97 citations

Cyclic AMP and Cell Behavior in Cultured Cells

1976 • 92 citations

Cell surface protein decreases microvilli and ruffles on transformed mouse and chick cells

1976 • 89 citations

Specific changes in the collagen phenotype of BALB 3T3 cells as a result of transformation by sarcoma viruses or a chemical carcinogen

1977 • 88 citations

Role of cell surface carbohydrates and proteins in cell behavior: studies on the biochemical reversion of an N-acetylglucosamine-deficient fibroblast mutant.

1977 • 85 citations

The role of surface proteins in cell proliferation as studied with thrombin and other proteases.

1975 • 84 citations

Intracellular Cyclic AMP Concentration Responds Specifically to Growth Regulation by Serum

1974 • 82 citations

Coordinate control of collagen synthesis and cell growth in chick embryo fibroblasts and the effect of viral transformation on collagen synthesis

1977 • 75 citations

Adenylate Cyclase Activity in Fibroblasts Transformed by Kirsten or Moloney Sarcoma Viruses

1974 • 75 citations

Transformation of Chick-Embryo Fibroblasts by Wild-Type and Temperature-Sensitive Rous Sarcoma Virus Alters Adenylate Cyclase Activity

1973 • 75 citations

Mutants of Balb/c 3T3 fibroblasts defective in adhesiveness to substratum: evidence for alteration in cell surface proteins.

1976 • 74 citations

Interrelationship Between Adenylate Cyclase Activity, Adenosine 3′:5′ Cyclic Monophosphate Phosphodiesterase Activity, Adenosine 3′:5′ Cyclic Monophosphate Levels, and Growth of Cells in Culture

1973 • 73 citations

Studies on the levels of cyclic AMP in cells transformed by wild-type and temperature-sensitive Kirsten sarcoma virus

1974 • 73 citations

Effect of Insulin on the Growth Pattern and Adenylate Cyclase Activity of BHK Fibroblasts

1973 • 72 citations

A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells.

1975 • 62 citations

CONCOMITANT EFFECTS OF INSULIN ON SURFACE MEMBRANE CONFORMATION AND POLYSOME PROFILES OF SERUM-STARVED BALB/C 3T3 FIBROBLASTS

1974 • 56 citations

Surface morphology and agglutinability with concanavalin A in normal and transformed murine fibroblasts.

1976 • 55 citations

High molecular weight MAPs are part of the mitotic spindle

1978 • 55 citations

Growth control in chick embryo fibroblasts; no evidence for a specific role for cyclic purine nucleotides

1974 • 51 citations

Identification of a transformation-specific protein induced by a rous sarcoma virus

1978 • 46 citations

Similarities in the membrane fluidity of 3T3 and SV101-3T3 cells and its relation to concanavalin A- and wheat germ agglutinin-induced agglutination.

1978 • 42 citations

Phosphorylation of filamin and other proteins in cultured fibroblasts

1977 • 38 citations

Adenylate cyclase activity is decreased in chick embryo fibroblasts transformed by wild type and temperature sensitive Schmidt-Ruppin Rous sarcoma virus

1973 • 37 citations

CYCLIC AMP MEDIATES THE CONCANAVALIN A AGGLUTINABILITY OF MOUSE FIBROBLASTS

1974 • 35 citations

Cyclic AMP levels in temperature sensitive SV40 transformed cell lines

1974 • 34 citations

A Mutant of 3T3 Cells with Cyclic AMP Metabolism Sensitive to Temperature Change

1973 • 29 citations

The role of microvilli in the agglutination of cells by concanavalin A

1977 • 28 citations

Multiple forms of sarc gene proteins from Rous sarcoma virus RNA.

1978 • 25 citations

Suppression of growth of L cells in suspension culture by dibutyryl adenosine 3′,5′-monophosphate

1973 • 22 citations

The relationship between cell surface protein and glucose and α‐aminoisobutyrate transport in transformed chick and mouse cells

1976 • 21 citations

Cyclic amp-induced morphological transformation of cells infected by temperature-sensitive mouse sarcoma virus: Expression of transformation-associated markers

1977 • 16 citations

F20C, a new fluorescent membrane probe, moves more slowly in malignant and mitogen-transformed cell membranes than in normal cell membranes

1978 • 14 citations

Expression of Virus Specific Morphological Cell Transformation Induced in E nucleated Cells

1976 • 11 citations

Cyclic AMP-mediated transformation of rat cells transformed by temperature-sensitive mouse sarcoma virus

1975 • 11 citations

Adenylate cyclase activity and the camp level are not directly correlated with transformation by avian sarcoma viruses

1977 • 5 citations