In vivotranscription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

Site-Specific Oligonucleotide Binding Represses Transcription of the Human c- myc Gene in Vitro

1988 • 707 citations

Progestin Regulation of Cellular Proliferation*

1990 • 659 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

Second Structural Motif for Recognition of DNA by Oligonucleotide-Directed Triple-Helix Formation

1991 • 530 citations

Inhibition of DNA Binding Proteins by Oligonucleotide-Directed Triple Helix Formation

1989 • 416 citations

Endocrine Treatment of Breast Cancer in Women

1990 • 403 citations

Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc mRNA levels.

1991 • 299 citations

Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements

1989 • 270 citations

Effects of phosphorothioate capping on antivense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

1991 • 242 citations

Specific inhibition of transcription by triple helix-forming oligonucleotides.

1992 • 241 citations

Binding of triple helix forming oligonucleotides to sites in gene promoters

1991 • 240 citations

Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.

1991 • 224 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

The anti-gene strategy: control of gene expression by triplex-forming-oligonucleotides.

1991 • 206 citations

Oligonucleotide inhibition of IL2Rα mRNA transcription by promoter region collinear triplex formation in lymphocytes

1991 • 183 citations

Triple helix formation inhibits transcription elongation in vitro.

1991 • 171 citations

A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence.

1992 • 169 citations

Identification of two factors required for transcription of the ovalbumin gene.

1986 • 166 citations

Site-Specific Cleavage of Human Chromosome 4 Mediated by Triple-Helix Formation

1991 • 160 citations

Rational design of sequence-specific oncogene inhibitors based on antisense and antigene oligonucleotides

1991 • 138 citations

Inhibition of transcription of HIV-1 in infected human cells by oligodeoxynucleotides designed to form DNA triple helices.

1992 • 136 citations

Inhibition of Simian Virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent

1990 • 119 citations

Sequence and Expression of a Functional Chicken Progesterone Receptor

1987 • 112 citations

Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription

1990 • 110 citations

Biotinyl and phosphotyrosinyl phosphoramidite derivatives useful in the incorporation of multiple reporter groups on synthetic oligonucleotides

1990 • 78 citations

In vitro and in vivo pharmacologic activities of antisense oligonucleotides.

1991 • 73 citations

Effective incorporation of 2'-O-methyl-oligoribonuclectides into liposomes and enhanced cell association through modification with thiocholesterol

1992 • 63 citations

Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70.

1991 • 59 citations

A far upstream ovalbumin enhancer binds nuclear factor-1-like factor.

1988 • 37 citations

A model for hormone receptor binding to the mouse mammary tumour virus regulatory element bared on hydroxyl radical footprinting

1988 • 35 citations

RU486 and the early nineties

1991 • 4 citations