Two separate functions of class II (Ia) molecules: T-cell stimulation and B-cell excitation.

Further improvements in the plaque technique for detecting single antibody-forming cells.

1968 • 2,171 citations

The carrier effect in the secondary response to hapten‐protein conjugates. II. Cellular cooperation

1971 • 677 citations

Studies on the capacity of B cells to serve as antigen-presenting cells.

1981 • 349 citations

Cooperative interaction of B lymphocytes with antigen-specific helper T lymphocytes is MHC restricted

1981 • 207 citations

T-cell-dependent B-cell stimulation is H-2 restricted and antigen dependent only at the resting B-cell level.

1980 • 191 citations

B Lymphocyte: Activation by Insoluble Anti-Immunoglobulin: Induction of Immunoglobulin Secretion by a T Cell-Dependent Soluble Factor

1979 • 128 citations

Dissociation of two signals required for activation of resting B cells.

1982 • 123 citations

A Suggested Mechanism for T Lymphocyte Activation: Implications on the Acquisition of Functional Reactivities

1980 • 104 citations

Antigen-specific T-helper cells stimulate H-2-compatible and H-2-incompatible B-cell blasts polyclonally.

1980 • 94 citations

Antigen-induced lymphomagenesis: identification of a murine B cell lymphoma with known antigen specificity.

1983 • 89 citations

Monoclonal antibodies against HLA-DR antigens replace T helper cells in activation of B lymphocytes.

1983 • 82 citations

Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex.

1977 • 79 citations

Selective reconstitution of nude mice with long-term cultured and cloned specific helper T cells

1980 • 73 citations

Activation of antigen-specific B cells: role of T cells, cytokines, and antigen in induction of growth and differentiation.

1983 • 64 citations

Major histocompatibility complex‐restricted cellular interactions determining B cell activation

1982 • 48 citations

Antigen-specific helper T-cell clone supernatant is sufficient to induce both polyclonal proliferation and differentiation of small resting B lymphocytes.

1984 • 48 citations

The role of B cell surface Ia antigen recognition by T cells in B cell triggering. Analysis of the interaction of cloned helper T cells with normal B cells in differing states of activation and with B cells expressing the xid defect

1984 • 46 citations

Positive and Negative Allogeneic Effects Mediated by MLR-Primed Lymphocytes: Quantitation by Limiting Dilution Analysis

1978 • 40 citations

B lymphocyte activation upon exclusive recognition of major histocompatibility antigens by T helper cells

1984 • 39 citations

Role of cell surface immunoglobulin in B-lymphocyte activation.

1984 • 36 citations

Two classes of bystander B cell response: activation requirements reflect those of B cells in general.

1983 • 29 citations

On the role of I‐A antigens in lectin‐ and antigen‐induced interleukin 2 production

1984 • 24 citations

Functional heterogeneity of helper T cells: two distinct helper T cells are required for the production of T cell growth factor.

1982 • 22 citations

Induced differentiation of a B cell lymphoma with known antigen specificity.

1984 • 17 citations

The Regulation of T Cell Growth: Requirements for the Activation and Replication of Antigen-Specific Interleukin 2 Producing T Cells

1982 • 17 citations

Major Histocompatibility Complex-Restricted and Unrestricted Interactions in the T Cell-Dependent Activation of Hapten-Binding B Cells

1984 • 11 citations

The effect of second signals on the induction of B cell tolerance: failure of helper T cells to block tolerance induction

1981 • 5 citations