Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains

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Brain Dopamine and Reward

1989 • 1,899 citations

Factors That Predict Individual Vulnerability to Amphetamine Self-Administration

1989 • 1,354 citations

On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine

1977 • 733 citations

The pharmacology of cocaine related to its abuse.

1989 • 685 citations

Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats

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Stress- and pharmacologically-induced behavioral sensitization increases vulnerability to acquisition of amphetamine self-administration

1990 • 574 citations

A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function

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Survival Distributions: Reliability Applications in the Biomedical Sciences

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Cocaine-reinforced behavior in rats: effects of reinforcement magnitude and fixed-ratio size.

1968 • 418 citations

Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine

1992 • 347 citations

Alcoholism and Heredity

1979 • 319 citations

Non-contingent electric footshock facilitates the acquisition of intravenous cocaine self-administration in rats

1994 • 284 citations

Preexposure sensitizes rats to the rewarding effects of cocaine

1990 • 273 citations

Nicotine self-administration in rats: strain and nicotine pre-exposure effects on acquisition

1997 • 234 citations

Morphine and Cocaine Exert Common Chronic Actions on Tyrosine Hydroxylase in Dopaminergic Brain Reward Regions

1991 • 211 citations

Differential establishment and maintenance of oral ethanol reinforced behavior in Lewis and Fischer 344 inbred rat strains.

1988 • 209 citations

Fischer and Lewis rat strains show differential cocaine effects in conditioned place preference and behavioral sensitization but not in locomotor activity or conditioned taste aversion.

1994 • 204 citations

Marijuana's interaction with brain reward systems: Update 1991

1991 • 199 citations

Neurofilament proteins and the mesolimbic dopamine system: common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area

1992 • 189 citations

Fischer and Lewis rat strains differ in basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system

1992 • 161 citations

The effects of methamphetamine and cocaine on motor behavior and extracellular dopamine in the ventral striatum of Lewis versus Fischer 344 rats

1994 • 149 citations

Intravenous Self-Administration: Response Rates, the Effects of Pharmacological Challenges, and Drug Preference

1987 • 148 citations

Genetic approaches to the analysis of addiction processes

1989 • 147 citations

Autoshaping i.v. cocaine self-administration in rats: effects of nondrug alternative reinforcers on acquisition

1993 • 143 citations

Behavior genetic investigation of the relationship between spontaneous locomotor activity and the acquisition of morphine self-administration behavior

1995 • 141 citations

Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol.

1989 • 134 citations

Dopaminergic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine- and cocaine-regulated phosphoproteins

1991 • 130 citations

Lewis and Fischer rat strains display differences in biochemical, electrophysiological and behavioral parameters: studies in the nucleus accumbens and locus coeruleus of drug naive and morphine-treated animals

1993 • 123 citations

Pharmacological regulation of intravenous cocaine and heroin self-administration in rats: A variable dose paradigm

1989 • 115 citations

Caffeine exposure sensitizes rats to the reinforcing effects of cocaine

1991 • 111 citations

Cocaine-induced conditioned taste aversions: comparisons between effects in LEW/N and F344/N rat strains

1994 • 89 citations

Determination of cocaine concentrations in plasma by high-performance liquid chromatography

1990 • 80 citations

Etonitazene delivered orally serves as a reinforcer for Lewis but not Fischer 344 rats

1992 • 78 citations

Tolerance to self-administration of cocaine in rats: time course and dose-response determination using a multi-dose method

1993 • 77 citations

Inbred rat strain comparisons indicate different sites of action for cocaine and amphetamine locomotor stimulant effects

1991 • 77 citations

Genetic differences in preferences for morphine and codeine in Lewis and Fischer 344 inbred rat strains.

1988 • 74 citations

Genetic approaches to drug dependence

1992 • 64 citations

Drug-reinforced responding: rapid determination of dose-response functions

1989 • 61 citations

Genetic Differences in Responses to Cocaine

1988 • 40 citations

Extracellular dopamine and its metabolites in the nucleus accumbens of fischer and lewis rats: Basal levels and cocaine-induced changes

1994 • 39 citations

Significant differences in the activity of midbrain dop amine neurons between male fischer 344 (f344) and lewis rats: an in vivo electrophysiological study

1995 • 33 citations

Genetic differences in the development of physical dependence on pentobarbital in four inbred strains of rats.

1987 • 25 citations

Reinforcer interactions under concurrent schedules of food, water, and intravenous cocaine

1990 • 19 citations

Differences in bioavailability between cocaine and cocaethylene and their implications for drug-reward studies

1994 • 19 citations

The use of pharmacogenetic techniques in drug abuse research

1992 • 15 citations

Water deprivation-induced oral self-administration of cocaine in the Lewis rat: Evidence for locomotor effects but not reinforcement

1993 • 13 citations

Genetic Differences in Preferences for Morphine and Codeine in Lewis and Fischer 344 Inbred Rat Strains

1988 • 13 citations

Biological Vulnerability to Drug Abuse: NIDA Research Monograph 89

1988 • 9 citations

The failure of cocaine to serve as an orally self-administered reinforcer in Lewis rats

1995 • 6 citations

Genetic Differences in the Development of Physical Dependence on Pentobarbital in Four Inbred Strains of Rats

1987 • 3 citations