Cytokines, chemokines, and cytokine receptors in human microglia

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

1993 • 832 citations

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

1993 • 789 citations

Extracellular Signal-Regulated Kinase and p38 Subgroups of Mitogen-Activated Protein Kinases Regulate Inducible Nitric Oxide Synthase and Tumor Necrosis Factor-α Gene Expression in Endotoxin-Stimulated Primary Glial Cultures

1998 • 709 citations

β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis

2001 • 678 citations

Production of superoxide anions by a CNS macrophage, the microglia

1987 • 619 citations

Microglia in degenerative neurological disease

1993 • 594 citations

LPS-binding proteins and receptors

1998 • 480 citations

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene.

1988 • 462 citations

Brain macrophages: evaluation of microglia and their functions

1992 • 443 citations

Identification of Microglial Signal Transduction Pathways Mediating a Neurotoxic Response to Amyloidogenic Fragments of β-Amyloid and Prion Proteins

1999 • 353 citations

Amyloid Fibrils Activate Tyrosine Kinase-Dependent Signaling and Superoxide Production in Microglia

1997 • 318 citations

Erythropoietin and Erythropoietin Receptors in Human CNS Neurons, Astrocytes, Microglia, and Oligodendrocytes Grown in Culture

2001 • 307 citations

Unwelcomed Guests with Master Keys: How HIV Uses Chemokine Receptors for Cellular Entry

1997 • 260 citations

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1998 • 253 citations

Cytology and Cellular Pathology of the Nervous System.

1932 • 245 citations

IL-4, IL-10 and IL-13 modulate Aβ(1–42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line

2001 • 237 citations

Cytokine Regulation of Human Microglial Cell IL-8 Production

1998 • 226 citations

Interleukin‐10 Inhibits Both Production of Cytokines and Expression of Cytokine Receptors in Microglia

1999 • 218 citations

Mitogen-activated protein kinases activated by lipopolysaccharide and β-amyloid in cultured rat microglia

1998 • 213 citations

β-Amyloid Fibrils Activate Parallel Mitogen-Activated Protein Kinase Pathways in Microglia and THP1 Monocytes

1998 • 201 citations

Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia.

1998 • 166 citations

Expression of cytokine receptors in cultured neuronal and glial cells

1993 • 161 citations

Microglia, Scavenger Receptors, and the Pathogenesis of Alzheimer’s Disease

1998 • 157 citations

Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with β-amyloid[25–35]

1999 • 155 citations

Generation and Characterization of Immortalized Human Microglial Cell Lines: Expression of Cytokines and Chemokines

2001 • 144 citations

Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microglia.

1992 • 144 citations

T-cell costimulatory molecules B7-1 (CD80) and B7-2 (CD86) are expressed in human microglia but not in astrocytes in culture

1995 • 143 citations

Cytokine Induction of MIP-1α and MIP-1β in Human Fetal Microglia

1998 • 143 citations

Cellular immune response in multiple sclerosis plaques.

1990 • 112 citations

Detection of lysosomal cysteine proteinases in microglia: Flow cytometric measurement and histochemical localization of cathepsin B and L

1993 • 109 citations

Genesis of resting microglia in the gray matter of mouse hippocampus

1984 • 107 citations

Macrophages in the central nervous system of the rat

1987 • 100 citations

IL-10 PRODUCTION BY ADULT HUMAN DERIVED MICROGLIAL CELLS

1996 • 92 citations

Development of microglia in the albino rabbit retina

1989 • 83 citations

Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome

1993 • 72 citations

Specific endotoxic lipopolysaccharide-binding receptors on murine splenocytes. III. Binding specificity and characterization.

1991 • 71 citations

HSP72 induction by heat stress in human neurons and glial cells in culture

1994 • 65 citations