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Immunosuppressive activity of the retroviral envelope protein P 15E and its possible relationship to neoplasia

Data up to Jan 2025

Published1984
Citations127
References50

Total Citations Per Year

Abstract

References (50)

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1980 • 1,778 citations

Contemporary Topics in Immunobiology

1977 • 410 citations

The phagocytic cell in host resistance

1975 • 297 citations

Human Mononuclear Leukocyte Chemotaxis: A Quantitative Assay for Humoral and Cellular Chemotactic Factors

1972 • 290 citations

ISOLATION OF NEW LYMPHOTROPIC RETROVIRUS FROM TWO SIBLINGS WITH HAEMOPHILIA B, ONE WITH AIDS

1984 • 251 citations

Immunodeficiency disease and malignancy. Various immunologic deficiencies of man and the role of immune processes in the control of malignant disease.

1972 • 206 citations

Assembly of Type C Oncornaviruses: A Model

1978 • 201 citations

Abnormal Monocyte Chemotactic Response in Cancer Patients

1974 • 171 citations

An Inhibitor of Macrophage Chemotaxis Produced by Neoplasms

1976 • 165 citations

Immunodeficiency Disease and Malignancy

1972 • 163 citations

Depression of macrophage function by a factor produced by neoplasms: a merchanism for abrogation of immune surveillance.

1976 • 158 citations

Interaction of BCG-Activated Macrophages With Neoplastic and Nonneoplastic Cell Lines in Vitro: Quantitation of the Cytotoxic Reaction by Release of Tritiated Thymidine From Prelabeled Target Cells

1975 • 137 citations

Abrogation of lymphocyte blastogenesis by a feline leukaemia virus protein

1978 • 135 citations

Immunosuppressive properties of a virion polypeptide, a 15,000-dalton protein, from feline leukemia virus.

1979 • 122 citations

Inhibitors of monocyte responses to chemotaxins are present in human cancerous effusions and react with monoclonal antibodies to the P15(E) structural protein of retroviruses.

1981 • 119 citations

Macrophage accumulation in mice is inhibited by low molecular weight products from murine leukemia viruses.

1980 • 110 citations

Depression of Macrophage Function by a Factor Produced by Neoplasms: A Mechanism for Abrogation of Immune Surveillance

1976 • 109 citations

Monocyte Responsiveness to Chemotactic Stimuli is a Property of a Subpopulation of Cells that can Respond to Multiple Chemoattractants

1981 • 105 citations

The mechanism of retrovirus suppression of human T cell proliferation in vitro.

1983 • 101 citations

Abnormalities of Monocyte Chemotaxis in Patients With Melanoma: Effects of Immunotherapy and Tumor Removal2

1977 • 97 citations

Abnormal Monocyte Chemotaxis in Patients With Breast Cancer: Evidence for a Tumor-Mediated Effect2

1978 • 88 citations

Inhibition of interleukin 2 production by factors released from tumor cells.

1983 • 87 citations

SEPTAL LINES

1976 • 86 citations

Defective Monocyte Function in Patients With Genitourinary Carcinoma 2

1975 • 82 citations

Cell-Specific Defect in Monocyte Function During Tumor Growth2

1976 • 77 citations

Macrophages and resistance to tumours. I. Inhibition of delayed-type hypersensitivity reactions by tumour cells and by soluble products affecting macrophages.

1978 • 74 citations

Inhibition of concanavalin A stimulation of feline lymphocytes by inactivated feline leukemia virus.

1977 • 64 citations

Murine malignant cells synthesize a 19,000-dalton protein that is physicochemically and antigenically related to the immunosuppressive retroviral protein, P15E.

1983 • 58 citations

Human malignant and mitogen-transformed cells contain retroviral P15E-related antigen.

1984 • 55 citations

Inhibition of human lymphocyte mitogen and antigen response by a 15,000-dalton protein from feline leukemia virus.

1979 • 54 citations

Abrogation of resistance to feline oncornavirus disease by immunization with killed feline leukemia virus.

1977 • 52 citations

Two-Step Mechanism of Tumor Graft Rejection in Syngeneic Guinea Pigs. II. Initiation of Reaction by a Cell Fraction Containing Lymphocytes and Neutrophils

1970 • 44 citations

Defective human mononuclear leukocyte chemotaxis as an index of host resistance to malignant melanoma

1976 • 43 citations

Depressed Chemotactic Responses In Vitro of Peritoneal Macrophages From Tumor-Bearing Mice2

1976 • 38 citations

Depression of Murine Macrophage Accumulation by Low-Molecular-Weight Factors Derived From Spontaneous Mammary Carcinomas2

1980 • 34 citations

Effect of Various Viruses on the Responsiveness of Mouse Lymphocytes to Phytohemagglutinin Stimulation

1973 • 34 citations

Active and Passive Immunization of Cats With Inactivated Feline Oncornaviruses 2

1977 • 32 citations

Subversion of host defense mechanisms by malignant tumors: an established tumor as a privileged site for bacterial growth.

1977 • 32 citations

Impaired macrophage function in Friend virus leukemia: restoration by statolon.

1975 • 28 citations

Inhibition of erythroid colony-forming cells by a Mr 15,000 protein of feline leukemia virus.

1984 • 26 citations

Immunosuppression Induced In Vitro by Cell-Free Extracts of Friend Leukemia Virus-Infected Splenocytes 2

1976 • 25 citations

Contemporary Topics in Immunobiology

1980 • 19 citations

Impaired Macrophage Function in Reiend Virus Leukemia: Restoration by Statolon

1975 • 19 citations

LEUKEMIA VIRUS‐INDUCED IMMUNOSUPPRESSION: REVERSAL BY SUBCELLULAR FACTORS*

1979 • 18 citations

Effects of Retrovirus Protein on the Feline One-way Mixed Leukocyte Reaction

1983 • 17 citations

Non-specific inhibition by virus particles of human lymphocytes mitogenesis.

1980 • 16 citations

Viral abrogation of lymphocyte mitogenesis: induction of a soluble factor inhibitory to cellular proliferation.

1980 • 12 citations

REVERSAL OF IMMUNOSUPPRESSION INDUCED BY MURINE LEUKEMIA VIRUSES*

1976 • 8 citations

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Immunosuppressive activity of the retroviral envelope protein P 15E and its possible… (1984) – Immunology Today | Metascience Observatory Explorer