Estrogen and Progesterone Receptor Determinations in Breast Cancer—Technology, Biology and Clinical Significance

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Histological Grading and Prognosis in Breast Cancer

1957 • 2,897 citations

ON THE TREATMENT OF INOPERABLE CASES OF CARCINOMA OF THE MAMMA: SUGGESTIONS FOR A NEW METHOD OF TREATMENT, WITH ILLUSTRATIVE CASES.

1896 • 1,633 citations

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

ON THE TREATMENT OF INOPERABLE CASES OF CARCINOMA OF THE MAMMA: SUGGESTIONS FOR A NEW METHOD OF TREATMENT, WITH ILLUSTRATIVE CASES.1

1896 • 1,240 citations

Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies.

1985 • 995 citations

Nuclear localization of unoccupied oestrogen receptors

1984 • 882 citations

EPIDERMAL-GROWTH-FACTOR RECEPTOR STATUS AS PREDICTOR OF EARLY RECURRENCE OF AND DEATH FROM BREAST CANCER

1987 • 881 citations

Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptor.

1978 • 797 citations

The value of estrogen and progesterone receptors in the treatment of breast cancer

1980 • 735 citations

Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer.

1977 • 694 citations

A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization.

1966 • 680 citations

Estrogen Receptors in Human Breast Cancer

1976 • 621 citations

Predicting Response to Endocrine Therapy in Human Breast Cancer: A Hypothesis

1975 • 570 citations

Monoclonal antibodies to human estrogen receptor.

1980 • 545 citations

Endogenous concentration and subcellular distribution of androgens in normal and malignant human breast tissue.

1985 • 446 citations

Estrogen receptors and breast cancer response to adrenalectomy.

1971 • 434 citations

Scatchard plots: Common errors in correction and interpretation

1975 • 411 citations

Correlations between estrogen receptor, progesterone receptor, and patient characteristics in human breast cancer.

1984 • 385 citations

Progesterone Receptors as a Prognostic Factor in Stage II Breast Cancer

1983 • 372 citations

Molecular Biology of the Human T-Lymphotropic Retroviruses

1986 • 324 citations

CONTROLLED TRIAL OF TAMOXIFEN AS SINGLE ADJUVANT AGENT IN MANAGEMENT OF EARLY BREAST CANCER

1985 • 291 citations

Prognostic value of estrogen receptors in primary breast cancer

1979 • 270 citations

Specific Estrogen Binding by the Cytoplasm of Human Breast Carcinoma

1970 • 234 citations

Nuclear retention of receptor–oestrogen complex and nuclear acceptor sites

1976 • 228 citations

Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas.

1986 • 214 citations

Steroid Receptors in Breast Cancer

1979 • 213 citations

BENEFICIAL EFFECT OF ADJUVANT TAMOXIFEN THERAPY IN PRIMARY BREAST CANCER PATIENTS WITH HIGH OESTROGEN RECEPTOR VALUES

1985 • 212 citations

Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene.

1987 • 199 citations

Steroid receptors in human breast cancer.

1978 • 172 citations

STUDIES WITH TRITIUM-LABELLED HEXŒSTROL IN ADVANCED BREAST CANCER

1961 • 167 citations

Selective accumulation of tritium-labelled hexoestrol by the reproductive organs of immature female goats and sheep

1959 • 162 citations

Immunohistologic localization of estrogen receptors in breast cancer with monoclonal antibodies. Correlation with biochemistry and clinical endocrine response

1985 • 159 citations

Relationship of presence of progesterone receptors to prognosis in early breast cancer.

1980 • 156 citations

Sulfhydryl Groups and Estradiol-Receptor Interaction

1967 • 151 citations

Prognostic value of steroid hormone receptors: multivariate analysis of systemically untreated patients with node negative primary breast cancer.

1987 • 150 citations

Receptor Molecule for Oestrogens from Rat Uterus

1968 • 145 citations

Protamine-precipitated estrogen receptor: A solid-phase ligand exchange assay

1975 • 138 citations

Standards for the assessment of estrogen receptors in human breast cancerReport of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis, Amsterdam

1973 • 130 citations

Estrogen receptor protein of breast cancer as a predictor of recurrence

1985 • 127 citations

Estrogen and progesterone receptor proteins in breast cancer

1979 • 124 citations

Oestradiol Receptors in Carcinoma and Benign Disease of the Breast: An In Vitro Assay

1971 • 116 citations

Prognostic usefulness of estrogen receptor immunocytochemical assays for human breast cancer.

1986 • 114 citations

MECHANISM OF ACTION OF ADJUVANT CHEMOTHERAPY IN EARLY BREAST CANCER

1986 • 94 citations

Towards a new model for the mechanism of action of steroids

1982 • 94 citations

Indirect mechanism of oestradiol stimulation of cell proliferation of human breast cancer cell lines

1986 • 89 citations

Estrogen Receptors in Target Tissues

1966 • 89 citations

Immunocytochemical staining of estrogen receptor in paraffin sections of human breast cancer by use of monoclonal antibody: comparison with that in frozen sections.

1985 • 84 citations

Organisation of the Danish adjuvant trials in breast cancer.

1981 • 83 citations

Abbott monoclonal enzyme immunoassay measurement of estrogen receptors in human breast cancer: a European multicenter study.

1986 • 81 citations

Estrogen receptor protein in breast cancer as a predictor of recurrence

1981 • 81 citations

Ueber Carcinoma mammae

1886 • 69 citations

Immunocytochemical detection of progesterone receptor in breast cancer with monoclonal antibody. Relation to biochemical assay, disease-free survival, and clinical endocrine response

1988 • 67 citations

Estrogen receptor values in patients with benign breast disease

1979 • 67 citations

Characterization of estrogen and progesterone receptors and the dissociated regulation of growth and progesterone receptor stimulation by estrogen in MDA-MB-134 human breast cancer cells.

1986 • 66 citations

Adjuvant treatment for early breast cancer: the Ludwig breast cancer studies.

1986 • 66 citations

Prognostic factors in primary breast cancer.

1986 • 65 citations

Standardization of steroid receptor assays in human breast cancer—I. Reproducibility of estradiol and progesterone receptor assays

1983 • 65 citations

Semiquantitative oestrogen receptor assay in formalin-fixed paraffin sections of human breast cancer tissue using monoclonal antibodies

1986 • 62 citations

Multiple steroid receptors in human breast cancer

1979 • 60 citations

PREDICTING RESPONSE TO ENDOCRINE THERAPY IN HUMAN BREAST CANCER

1976 • 59 citations

A hydroxylapatite micromethod for measuring estrogen receptor in human breast cancer.

1978 • 59 citations

Histologic malignancy grading of invasive ductal breast carcinoma. A regression analysis of prognostic factors in low-risk carcinomas from a multicenter trial

1987 • 58 citations

Evidence that estrogen-receptor-negative, progesterone-receptor-positive breast and ovarian carcinomas contain estrogen receptor

1981 • 57 citations

Steroid receptors in breast cancer: Sources of inter-laboratory variation in dextran-charcoal assays

1987 • 56 citations

Monoclonal antibody technique for detection of estrogen receptors in human breast cancer: greater sensitivity and more accurate classification of receptor status than the dextran-coated charcoal method.

1987 • 56 citations

Subcellular compartmentalization of estrogen receptors in human breast cancer cells

1980 • 56 citations

Standardization of steroid receptor assays in human breast cancer—IV. Long-term within- and between-laboratory variation of estrogen and progesterone receptor assays

1986 • 56 citations

Immunological Approaches to the Diagnosis and Therapy of Breast Cancer

1987 • 53 citations

NUCLEAR $OElig;STROGEN RECEPTORS AND TREATMENT OF BREAST CANCER

1977 • 51 citations

Oestrogen and progesterone receptor determinations in breast cancer: technology and biology.

1986 • 47 citations

Oestrogen and progesterone receptors and disease-free interval in primary breast cancer

1984 • 46 citations

Endocrinology: New model for steroid hormone receptors?

1984 • 45 citations

A quality control study to assess the inter-laboratory variability of routine estrogen and progesterone receptor assays

1982 • 44 citations

Oestrogen receptors in human breast cancer: review of histopathological correlations and critique of histochemical methods.

1983 • 43 citations

Factors influencing the estimation of oestrogen receptors in human malignant breast tumours

1975 • 41 citations

Soluble and nuclear oestrogen receptor status in human breast cancer in relation to prognosis

1981 • 40 citations

Quantitative immunological detection of estrogen receptors in nuclear pellets from human breast cancer biopsies.

1986 • 40 citations

Reliability of steroid hormone receptor assays: an international study

1983 • 39 citations

Standardization of steroid receptor assays in human breast cancer—II. Samples with low receptor content

1983 • 38 citations

Steroid hormone receptors as prognostic indicators in primary breast cancer.

1986 • 36 citations

Anti‐estrogen treatment of postmenopausal breast cancer patients with high risk of recurrence: 72 months of life‐table analysis and steroid hormone receptor status

1985 • 36 citations

Standardization of steroid receptor assays in human breast cancer—III. Selection of reference material for intra- and inter-laboratory quality control

1986 • 33 citations

Immunological quantitation of nuclear receptors in human breast cancer: relation to cytosolic estrogen and progesterone receptors.

1987 • 29 citations

The influence of hormone receptors and hormonal adjuvant therapy on disease-free survival in breast cancer: a multifactorial analysis

1986 • 28 citations

Six-year results of a controlled trial of tamoxifen as single adjuvant agent in management of early breast cancer

1985 • 26 citations

Conformational Forms of the Estrogen Receptor

1978 • 26 citations

A comparison of tumor-related antigens in male and female breast cancer

1986 • 25 citations

Enzyme immunoassay of estrogen receptors in fine needle aspirates of breast tumors.

1986 • 24 citations

Inter-laboratory quality control of estrogen and progesterone receptor assays in breast cancer tissue using lyophilised cytosols

1985 • 24 citations

Isoelectric focusing of estradiol receptor protein from human mammary carcinoma—a comparison to sucrose gradient analysis

1976 • 22 citations

A comparison of two steroid receptor assays in breast cancer: dextran coated charcoal and isoelectric focusing.

1983 • 22 citations

Estrogen and progesterone receptor profile patterns in primary breast cancer

1983 • 21 citations

Intracellular distribution of estrogen receptors: A function of preparation

1980 • 20 citations

Steroid Hormone Receptors and Disease: Breast Cancer

1979 • 18 citations

Stability of estrogen receptors in frozen human breast tumor tissue.

1979 • 16 citations

Quality control of estrogen receptor assays in the Netherlands

1983 • 14 citations

Postmenopausal Breast Cancer

1993 • 13 citations

Immunostaining of Estrogen Receptors in Paraffin Sections of Breast Cancers Using Anti-Estrophilin Monoclonal Antibodies

1985 • 10 citations

Nuclear estradiol-binding sites in human breast cancer.

1983 • 9 citations

Studies on nuclear estradiol receptors in human mammary carcinomas

1982 • 8 citations

Biological and clinical relevance of Kd values for estradiol binding in primary breast cancer tumors

1988 • 6 citations

Quality Control of Estrogen and Progesterone Receptor Analyses in Denmark

1984 • 5 citations