N-glycosylation of serum proteins in disease and its investigation using lectins

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG

1985 • 1,136 citations

GLYCOBIOLOGY

1988 • 1,107 citations

The carbohydrate-binding specificity of pea and lentil lectins. Fucose is an important determinant.

1981 • 568 citations

Identification of concanavalin A-binding proteins after sodium dodecyl sulfate-gel electrophoresis and protein blotting

1982 • 372 citations

FRACTIONATION AND STRUCTURAL ASSESSMENT OF OLIGOSACCHARIDES AND GLYCOPEPTIDES BY USE OF IMMOBILIZED LECTINS

1987 • 357 citations

Age-related galactosylation of the N-linked oligosaccharides of human serum IgG.

1988 • 290 citations

Characterization of N-linked oligosaccharides by affinoblotting with concanavalin A-peroxidase and treatment of the blots with glycosidases

1985 • 222 citations

GALACTOSYLATION OF IgG ASSOCIATED OLIGOSACCHARIDES: REDUCTION IN PATIENTS WITH ADULT AND JUVENILE ONSET RHEUMATOID ARTHRITIS AND RELATION TO DISEASE ACTIVITY

1988 • 221 citations

Crossed immuno-affinoelectrophoresis

1973 • 221 citations

Glycoprotein detection in nitrocellulose transfers of electrophoretically separated protein mixtures using concanavalin A and peroxidase: Application to arenavirus and flavivirus proteins

1982 • 185 citations

Abnormal glycosylation of serum igg from patients with chronic inflammatory diseases

1988 • 167 citations

Altered glycosylation of serum transferrin of patients with hepatocellular carcinoma

1989 • 166 citations

The fucosylation index of alpha-fetoprotein and its usefulness in the early diagnosis of hepatocellular carcinoma

1988 • 165 citations

Effect of Pregnancy and Hormonal Changes on the Activity of Rheumatoid Arthritis

1983 • 158 citations

Microheterogeneity of Alpha‐fetoprotein in Patient Serum as Demonstrated by Lectin Affino‐electrophoresis

1981 • 153 citations

REDUCED B-CELL GALACTOSYLTRANSFERASE ACTIVITY IN RHEUMATOID ARTHRITIS

1987 • 141 citations

Structural carbohydrates in the liver

1984 • 141 citations

Analysis of N-linked oligosaccharide chains of glycoproteins on nitrocellulose sheets using lectin-peroxidase reagents

1985 • 136 citations

Evidence for alpha-1-acid glycoprotein populations of different pI values after concanavalin a affinity chromatography Study of their evolution during inflammation in man

1981 • 126 citations

Evidence of a Reduced Sialic Acid Content in Serum Transferrin in Male Alcoholics

1981 • 126 citations

Fucosylation of serum α-fetoprotein in patients with primary hepatocellular carcinoma

1985 • 121 citations

Carbohydrate‐Deficient Transferrin in Serum in Patients with Liver Diseases

1987 • 120 citations

Isoelectric focusing and electrophoresis of the CSF proteins in tremor of different origins

1976 • 117 citations

Glycosylation of three molecular forms of human α₁‐acid glycoprotein having different interactions with concanavalin A

1988 • 114 citations

Structure of the asparagine-linked sugar chains of alpha-fetoprotein purified from human ascites fluid.

1980 • 113 citations

Protein blotting: Detection of proteins with colloidal gold, and of glycoproteins and lectins with biotin-conjugated and enzyme probes

1985 • 108 citations

Quantitative estimation of abnormal microheterogeneity of serum transferrin in alcoholics

1980 • 102 citations

α1-antitrypsin microheterogeneity

1982 • 100 citations

Carbohydrate Composition of Serum Transferrin in Alcoholic Patients

1986 • 100 citations

Structural changes of carbohydrate chains of human thyroglobulin accompanying malignant transformations of thyroid glands

1984 • 99 citations

Microheterogeneity forms of alpha1-acid glycoprotein as indicators of rheumatoid arthritis activity

1987 • 87 citations

Elevated levels of abnormally-fucosylated haptoglobins in cancer sera

1987 • 87 citations

Analysis of glycosylation changes in IgG using lectins

1990 • 81 citations

Sugar chain of alpha-fetoprotein produced in human yolk sac tumor.

1983 • 79 citations

Enzyme-linked lectin assay (ELLA): Use of alkaline phosphatase-conjugated Griffonia simplicifolia B4 isolectin for the detection of α-d-galactopyranosyl end groups

1983 • 78 citations

The microheterogeneity of human transferrins in biological fluids

1983 • 78 citations

Microheterogeneity of alpha₁‐acid glycoprotein in the detection of intercurrent infection in systemic lupus erythematosus

1987 • 77 citations

Relation between raised concentrations of fucose, sialic acid, and acute phase proteins in serum from patients with cancer: choosing suitable serum glycoprotein markers.

1985 • 76 citations

Alterations in carbohydrate composition of serum IgG from patients with rheumatoid arthritis and from pregnant women.

1988 • 73 citations

125I-wheat germ agglutinin blotting: Increased sensitivity with polyvinylpyrrolidone quenching and periodate oxidation/reductive phenylamination

1984 • 71 citations

The microheterogeneity of α1-acid glycoprotein in inflammatory lung disease, cancer of the lung and normal health

1984 • 71 citations

Variations in the relative proportions of microheterogeneous forms of plasma glycoproteins in pregnancy and disease.

1982 • 71 citations

Alpha1-acid glycoprotein: genetics, biochemistry, physiological functions and pharmacology

1989 • 71 citations

Increased concentrations of a transferrin variant after alcohol abuse

1984 • 68 citations

Presence of fucosylated triantennary, tetraantennary and pentaantennary glycans in transferrin synthesized by the human hepatocarcinoma cell line Hep G2

1989 • 68 citations

Serum alpha-fetoprotein and its lectin reactivity in liver diseases: a review.

1990 • 66 citations

Human serum sialo transferrins in diseases

1987 • 63 citations

Use of chromatofocusing to detect a transferrin variant in serum of alcoholic subjects.

1985 • 62 citations

N-Acetylglucosaminyltransferase III in human serum, and liver and hepatoma tissues: Increased activity in liver cirrhosis and hepatoma patients

1989 • 56 citations

Differential reactivity of alpha-fetoprotein with lectins and evaluation of its usefulness in the diagnosis of hepatocellular carcinoma.

1984 • 55 citations

Serum IgA, acute phase proteins, and glycosylation of alpha 1-acid glycoprotein in ankylosing spondylitis.

1989 • 54 citations

Structures, function, and transformational changes of the sugar chains of glycohormones

1988 • 53 citations

Structure and function of glycoproteins.

1967 • 51 citations

Abnormally-fucosylated serum haptoglobins in patients with inflammatory joint disease

1989 • 50 citations

Alterations in relative proportions of microheterogenous forms of human α1-acid glycoprotein in liver disease

1986 • 50 citations

Serum alpha fetoprotein heterogeneity as a means of differentiating between primary hepatocellular carcinoma and hepatic secondaries

1984 • 46 citations

Microheterogeneity of alpha₁‐acid glycoprotein in the detection of intercurrent infection in patients with rheumatoid arthritis

1989 • 45 citations

Biological Activities of Alpha1-fetoprotein

1988 • 45 citations

Abnormally-fucosylated haptoglobin: a cancer marker for tumour burden but not gross liver metastasis

1991 • 42 citations

Preparation and properties of glycosylated cytochemical markers

1977 • 42 citations

Alterations in the carbohydrate moiety of alpha-1-acid glycoprotein purified from human cirrhotic ascitic fluid

1987 • 40 citations

Measurement of Serum α1-Acid Glycoprotein and cei-Antitrypsin Desialylation in Liver Disease

1983 • 38 citations

Lentil-lectin-reactive alpha-fetoprotein in the differential diagnosis of benign and malignant liver disease.

1986 • 38 citations

Electrophoretic analysis of the glycan microheterogeneity of orosomucoid in cancer and inflammation

1986 • 37 citations

The microheterogeneity components of orosomucoid and the dissociation constants and mobilities of concanavalin A/corosomucoid complexes in crossed affinoimmunoelectrophoresis with free concanavalin A

1984 • 37 citations

Microheterogeneity of the carbohydrate moiety of human alpha 1-acid glycoprotein in two benign liver diseases: Alcoholic cirrhosis and acute hepatitis

1989 • 36 citations

Fucosylated forms of alpha-1-antitrypsin that predict unresponsiveness to chemotherapy in ovarian cancer

1988 • 36 citations

Studies of the sialylation and microheterogeneity of human serum α1-acid glycoprotein in health and disease

1987 • 36 citations

Characterization of oligosaccharides by lectin affinity high-performance liquid chromatography

1989 • 35 citations

Structures of the oligosaccharide chains of two forms of alpha 1-acid glycoprotein purified from liver metastases of lung, colon, and breast tumors.

1984 • 35 citations

α-Fetoprotein antibody-lectin enzyme immunoassay to characterize sugar chains for the study of liver diseases

1989 • 34 citations

Modifications of Concanavalin A patterns of α1-acid glycoprotein and α2-HS glycoprotein in alcoholic liver disease

1988 • 34 citations

The surface glycoproteins of human skin fibroblasts detected after electrophoresis by the binding of peanut (Arachis hypogaea) agglutinin and Ricinus communis (castor-bean) agglutinin I.

1982 • 32 citations

Structure determination of the glycans of human‐serum α₁‐antichymotrypsin using ¹H‐NMR spectroscopy and deglycosylation by N‐glycanase

1991 • 32 citations

Structure and Function of Glycoproteins

1975 • 32 citations

Affinity chromatographic separation of alpha-fetoprotein variants: development of a mini-column procedure, and application to cancer patients.

1986 • 31 citations

Rheumatoid Arthritis as a Glycosylation Disorder

1988 • 28 citations

An enzyme-linked lectin binding assay for quantitative determination of lectin receptors

1984 • 27 citations

Asialoglycoproteinemia in a case of primary hepatic cancer.

1980 • 26 citations

Differential reactivity of α-fetoprotein with lectins and its usefulness in the diagnosis of various liver diseases

1987 • 25 citations

Affinity electrophoresis of glycoproteins

1982 • 25 citations

Evaluation of the degree of desialylation of serum α1-acid glycoprotein and α1-antitrypsin

1982 • 24 citations

A multiwell lectin-binding assay using Lotus tetragonolobus for measuring different glycosylated forms of haptoglobin

1989 • 23 citations

Solid Phase Biochemistry — Analytical and Synthetic Aspects.

1984 • 23 citations

The reactivity of alpha-1-antitrypsin with Lens culinaris agglutinin and its usefulness in the diagnosis of neoplastic diseases of the liver

1987 • 23 citations

True and false glycoprotein microheterogeneity observed with lectin crossed affinoimmunoelectrophoresis of inter‐alpha‐trypsin‐inhibitor

1980 • 22 citations

The Oligosaccharides of Plasma Glycoproteins: Synthesis, Structure, and Function

1984 • 21 citations

Detection of carbohydrates with lectin-peroxidase conjugates.

1977 • 21 citations

A simple, reproducible and cheap batch method for the analysis of serum glycoproteins using Sepharose-coupled lectins and silver staining

1987 • 20 citations

Lectin-enzyme immunoassay of transferrin sialovariants using immobilized antitransferrin and enzyme-labeled galactose-binding lectin from Ricinus communis

1987 • 19 citations

Microheterogeneity of α1-acid glycoprotein: Lack of discrimination between benign and malignant inflammatory disease of the lung

1985 • 19 citations

Demonstration of Glycosylation Variants of Human Fibrinogen, Using the New Technique of Glycoprotein Lectin Immunosorbent Assay (GLIA)

1988 • 19 citations

Involvement of sialic acid residues in electroimmunodiffusion of α1-acid glycoprotein. A method for determining the degree of sialylation of serum glycoproteins

1981 • 16 citations

Early Diagnosis of Hepatocellular Carcinoma with Lectin Electrophoresis of Serum Alpha-Fetoprotein

1988 • 15 citations

Serum alpha-fetoprotein subfractions in hepatic malignancies identified by different reactivities with concanvalin A, lentil lectin or phytohemagglutinin-E

1986 • 13 citations

A Lectin-Based Monoclonal Enzyme Immunoassay to Distinguish Fucosylated and Non-Fucosylated α-Fetoprotein Molecular Variants

1990 • 13 citations

Chapter 23 Detection of Carbohydrates with Lectin—Peroxidase Conjugates

1977 • 12 citations

Crossed affino‐immunoelectrophoresis or affino‐blotting with lectins: Advantages and limitations for glycoprotein studies

1989 • 12 citations

Studies on microheterogeneity of acute-phase proteins in rheumatoid arthritis by using crossed affinoimmuno-electrophoresis with free concanavalin A.

1986 • 11 citations

Crossed Immunoaffinity Electrophoresis of Human Transferrin in Normal and Cirrhotic Sera

1984 • 10 citations

Evaluation of the degree of desialylation of serum C1-inactivator and haemopexin

1984 • 10 citations

Heterogeneity in copper and glycan content of ceruloplasmin in human serum differs in health and disease

1988 • 9 citations

The determination of asialoglycoforms of serum glycoproteins by lectin blotting with Ricinuscommunis agglutinin

1992 • 9 citations

Microheterogeneity of alpha 1-acid glycoprotein in the sera of patients with cancer or inflammatory states of the ovaries.

1988 • 8 citations

Changes in the Relative Amount of Individual Microheterogeneous Eorms of Serum Alpha-l-Antichymotrypsin in Disease

1982 • 6 citations

Studies of lotus-extracted haptoglobin in inflammatory bowel disease

1991 • 6 citations

Development of Concanavalin A-Enzyme Immunosorbent Assay for Glycated Haptoglobin Using Polyclonal and Monoclonal Antibodies

1992 • 4 citations

Role of sialic acid residues in crossed immuno‐affinoelectrophoresis of α₁‐proteinase inhibitor

1990 • 3 citations

Glycoforms of human serum proteins identified by Ricinus communis lectin

1990 • 2 citations

Further Control Experiments with Lectins to Assess Microheterogeneity of Glycoproteins

1982 • 2 citations

RAPID METHODS FOR THE DEMONSTRATION OF SUGAR RESIDUES IN TISSUE EXTRACTS, FLUIDS AND LECTINS IN PLANT EXTRACTS

1983 • 2 citations

THREE-DIMENSIONAL AFFINITY ELECTROPHORESIS OF HUMAN ALPHAFETO-PROTEIN

1981 • 2 citations

An Elisa Technique for Measurement of Transferrin Glyco-Variants in Body Fluids Using Lectins Bound to a Solid Phase

1984 • 1 citations