Use of a murine T-cell hybridoma expressing human T-cell receptor α- and β-gene products as a tool for the production of human T-cell receptor-specific monoclonal antibodies

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines

1979 • 1,885 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy

1989 • 394 citations

Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens

1990 • 301 citations

The fine specificity of antigen and la determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c

1982 • 244 citations

Idiotype-like molecules on cells of a human T cell leukemia.

1983 • 126 citations

The human thymus microenvironment: heterogeneity detected by monoclonal anti-epithelial cell antibodies.

1985 • 124 citations

Thy-1- and Ly-6-mediated lymphokine production and growth inhibition of a T cell hybridoma require co-expression of the T cell antigen receptor complex.

1988 • 103 citations

Inherited polymorphism of the human T-cell antigen receptor detected by a monoclonal antibody.

1986 • 81 citations

Autoimmune T cells: Immune recognition of normal and variant peptide epitopes and peptide-based therapy

1989 • 81 citations

Properties of a panel of monoclonal antibodies which react with the human T cell antigen receptor on the leukemic line HPB-ALL and a subset of normal peripheral blood T lymphocytes.

1986 • 80 citations

Anti-idiotypic monoclonal antibody to a T-cell chronic lymphatic leukemia

1989 • 57 citations

Prevalence of antigen receptor variants in human T cell lines and tumors.

1989 • 53 citations

Fine mapping of HLA class II monoclonal antibody specificities using transfected L cells

1990 • 26 citations

Generation of monoclonal antibodies against soluble human T cell receptor polypeptides

1991 • 25 citations

Determination of the molecular nature and cellular localization of Thy-1 in human renal tissue.

1990 • 16 citations

Co-expression of human T cell receptor chains with mouse CD3 on the cell surface of a mouse T cell hybridoma

1992 • 15 citations