In vivo and in vitro effects of a new macrolide antibiotic roxithromycin on rat liver cytochrome P-450: Comparison with troleandomycin and erythromycin

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Identification of an inducible form of cytochrome P-450 in human liver.

1985 • 320 citations

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

1985 • 301 citations

Cytochrome P-450 Monooxygenase Activities in Human and Rat Liver Microsomes

1981 • 173 citations

Dual effects of macrolide antibiotics on rat liver cytochrome P-450

1983 • 116 citations

Effects of erythromycin on hepatic drug-metabolizing enzymes in humans

1983 • 104 citations

Self-induction by triacetyloleandomycin of its own transformation into a metabolite forming a stable 456 nm-absorbing complex with cytochrome P-450

1981 • 98 citations

Formation of an inactive cytochrome P-450 Fe(II)-metabolite complex after administration of troleandomycin in humans

1982 • 88 citations

Fluorimetric determination of erythromycin and erythromycin ethylsuccinate in serum by a high-performance liquid chromatographic post-column, on-stream derivatization and extraction method

1978 • 83 citations

Formation of inactive cytochrome P-450 Fe(II)-metabolite complexes with several erythromycin derivatives but not with josamycin and midecamycin in rats

1983 • 80 citations

A study of the interaction of roxithromycin with theophylline and carbarmazepine

1987 • 44 citations

The cytochrome P-450 metabolite complex derived from troleandomycin: Properties in vitro and stability in vivo

1984 • 31 citations

Induction by Triacetyloleandomycin and partial purification of a LM3 form of cytochrome P-450 from rabbit liver microsomes

1982 • 26 citations

The effects of erythromycin on the absorption and disposition kinetics of theophylline

1981 • 24 citations

Some erythromycin derivatives are strong inducers in rats of a cytochrome P-450 very similar to that induced by 16 α-pregnenol one carbonitrile

1985 • 22 citations

Effects of troleandomycin administration on cholesterol 7 alpha-hydroxylase activity and bile secretion in rats.

1981 • 13 citations

Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver.

1986 • 11 citations

The pre-junctional site of action of Enhydrina schistosa venom at the neuromuscular junction

1973 • 7 citations

[Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro].

1987 • 1 citations