Total and Free Plasma Tryptophan Levels in Patients With Affective Disorders

Diagnostic Criteria for Use in Psychiatric Research

1972 • 5,688 citations

The Biochemistry of Affective Disorders

1967 • 1,183 citations

Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan Levels

1971 • 1,006 citations

The determination of tryptophan in plasma, liver, and urine.

1967 • 826 citations

Multivariate Analysis: Techniques for Educational and Psychological Research

1975 • 679 citations

The Specific Binding of l-Tryptophan to Serum Albumin

1958 • 638 citations

Lithium Carbonate and Imipramine in Prevention of Affective Episodes

1973 • 450 citations

5-Hydroxytryptamine in the Hind-Brain of Depressive Suicides

1967 • 424 citations

Free Tryptophan in Plasma and Brain Tryptophan Metabolism

1972 • 380 citations

5-HYDROXYINDOLE COMPOUNDS IN THE CEREBROSPINAL FLUID OF PATIENTS WITH PSYCHIATRIC OR NEUROLOGICAL DISEASES

1966 • 375 citations

NORADRENALINE, 5-HYDROXYTRYPTAMINE, AND 5-HYDROXYINDOLEACETIC ACID IN HINDBRAINS OF SUICIDAL PATIENTS

1968 • 304 citations

TRYPTOPHAN IN THE TREATMENT OF DEPRESSION

1967 • 274 citations

Antidepressant Response to Tricyclics and Urinary MHPG in Unipolar Patients

1975 • 269 citations

Psychomotor Activity and Cerebrospinal Fluid Amine Metabolites in Affective Illness

1973 • 263 citations

5-HYDROXYTRYPTAMINE, NORADRENALINE, AND DOPAMINE IN BRAINSTEM, HYPOTHALAMUS, AND CAUDATE NUCLEUS OF CONTROLS AND OF PATIENTS COMMITTING SUICIDE BY COAL-GAS POISONING

1969 • 259 citations

Regular Induction of Hypomania by L-Dopa in “Bipolar” Manic-depressive Patients

1971 • 257 citations

5-Hydroxyindoleacetic Acid Levels in the Cerebrospinal Fluid of Depressive Patients treated with Probenecid

1970 • 253 citations

The Comparative Antidepressant Value of L-Tryptophan and Imipramine With and Without Attempted Potentiation by Liothyronine

1972 • 248 citations

Cerebrospinal Fluid Amine Metabolites in Affective Illness: The Probenecid Technique

1973 • 245 citations

Lithium Response in Unipolar Versus Bipolar Depression

1972 • 222 citations

ACID MONOAMINE METABOLITES OF CEREBROSPINAL FLUID IN MENTAL DEPRESSION AND MANIA

1966 • 215 citations

5-hydroxyindoleacetic acid (and homovanillic acid) levels in the cerebrospinal fluid after probenecid application in patiens with manic-depressive psychosis

1969 • 189 citations

Monoamine metabolites in lumbar CSF: The question of their origin in relation to clinical studies

1974 • 189 citations

POSTPARTUM PSYCHOSES IN PATIENTS WITH MANIC DEPRESSIVE DISEASE

1970 • 187 citations

Unipolar and Bipolar Affective Illness

1971 • 172 citations

TOTAL AND FREE TRYPTOPHAN CONCENTRATION IN THE PLASMA OF DEPRESSIVE PATIENTS

1973 • 163 citations

Serotonin and Central Nervous System Function

1973 • 159 citations

AER in affective disorders.

1971 • 147 citations

Evidence for X-Linkage in the Transmission of Manic-Depressive Illness

1972 • 142 citations

EFFECTS ON PLASMA AND BRAIN TRYPTOPHAN IN THE RAT OF DRUGS AND HORMONES THAT INFLUENCE THE CONCENTRATION OF UNESTERIFIED FATTY ACID IN THE PLASMA

1974 • 141 citations

A pilot study of the predictive value of the probenecid test in application of 5-hydroxytryptophan as antidepressant

1972 • 131 citations

Cerebrospinal Fluid Levels of MHPG in Affective Disorders

1972 • 124 citations

Origin of 5-Hydroxyindoleacetic Acid in the Spinal Fluid

1971 • 122 citations

Rapid elevation of biogenic amine metabolites in human CSF following probenecid

1970 • 114 citations

l-Tryptophan in affective disorders: Indoleamine changes and differential clinical effects

1974 • 111 citations

Amine Precursors and Depression

1975 • 110 citations

Humoral Changes in Manic-Depressive Psychosis with Particular Reference to the Excretion of Catechol Amines in Urine

1958 • 98 citations

Clinical measurements of central dopamine and 5-hydroxytryptamine metabolism: reliability and interpretation of cerebrospinal fluid acid monoamine metabolite measures

1972 • 95 citations

Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the cerebrospinal fluid of patients with affective illness

1973 • 94 citations

Dietary Carbohydrate Increases Brain Tryptophan and Decreases Free Plasma Tryptophan

1973 • 89 citations

A method for the estimation of free and total acid-soluble plasma tryptophan using an ultrafiltration technique

1973 • 87 citations

Increase of Brain Tryptophan caused by Drugs which stimulate Serotonin Synthesis

1971 • 81 citations

The influence of sex, age and breast cancer on tryptophan metabolism

1967 • 71 citations

Influence of convulsive therapy on 5-hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid in endogenous depression

1971 • 69 citations

Catecholamines and exercise-induced glucagon and fatty acid mobilization in the rat

1975 • 49 citations

Cerebrospinal fluid 5-hydroxyindoles and behavior after l-tryptophan and pyridoxine administration to psychiatric patients

1970 • 45 citations

Types of Depressive Illness

1972 • 39 citations

Tryptophan metabolism in depressive illness

1974 • 33 citations

Aromatic amino acid decarboxylase inhibitors.

1971 • 31 citations

Unesterified Fatty Acids and the Binding of Tryptophan in Human Plasma

1974 • 30 citations

Whole Blood 5-Hydroxytryptamine during Treatment of Endogenous Depressive Illness

1973 • 29 citations

Comparable therapeutic efficacy of tryptophan and imipramine: average therapeutic ratings versus "true" equivalence. An important difference.

1973 • 20 citations

Multicompartmental analysis of amino acids: 1. Preliminary data on concentrations, fluxes, and flow constants of tryptophan in affective illness

1975 • 18 citations

Indoleamine metabolism in affective disorders: Excretion of tryptamine, indoleacetic acid and 5-hydroxyindoleacetic acid in depressive states

1972 • 11 citations

The origin of blood 5-hydroxyindoleacetic acid following L-hydrazino-α-methyldopa (MK-486)

1975 • 6 citations